Howard Hughes Medical Institute
Natural Selection and Evolution of Rock Pocket Mouse Populations
Can evolution repeat itself? Scholars analyze amino acid data in two separate populations of mice. They learn that evolution repeats itself, but natural selection prefers some mutations over others in different environments. Analysis...
Howard Hughes Medical Institute
The Molecular Evolution of Gene Birth and Death
More than 90 percent of humans' DNA doesn't code for anything! Scholars watch a presentation as they answer questions relating to gene mutations. They read details, watch videos, and view animations supporting the concepts. The questions...
Howard Hughes Medical Institute
Icefish Blood Adaptations: Viscosity
Most fish freeze to death when the water is too cold, yet some fish live in the Southern Ocean where the water is often below freezing. Scholars use two models representing the blood from most fish versus the blood from Antarctic fish....
Howard Hughes Medical Institute
How Do Fibers Form?
The proteins inside a cell determine the shape of the cell. While most red blood cells have a circular shape, those with sickle cell take the shape of a sickle. This change in shape causes multiple issues in the system. Scholars solve...
Howard Hughes Medical Institute
Population Genetics, Selection, and Evolution
The Hardy-Weinberg principle states that alleles and genotypes remain constant in the absence of evolutionary influences. Scholars complete a simple hands-on activity applying the Hardy-Weinberg principle to sample data. They observe how...
Howard Hughes Medical Institute
Weighing the Evidence for a Mass Extinction Part 2: On Land
What can fossils tell us about periods of extinction? Young scholars interpret fossil layers to make conclusions about changes in life during different geological time periods. They analyze the fossils for abundance and diversity as well...
Serendip
Evolution of Fur Color in Mice – Mutation, Environment and Natural Selection
Most species of animals include a variety of fur or hair color, but why? Scholars watch a video about a changing environment for mice. As the rocks around them change hues, different colors of mice begin to thrive. Discussion questions...
Howard Hughes Medical Institute
Biodiversity and Evolutionary Trees
Compare what shells look like on the outside with what makes that happen on the inside. Scholars begin by sorting an various seashells by their physical characteristics into phylogenetic trees. They then conduct a DNA comparison of...
Howard Hughes Medical Institute
Beaks as Tools: Selective Advantage in Changing Environments
How does nature select some adaptations over others? Scholars experiment picking up seeds with two different types of tools simulating beaks. After practicing, they experience a drought where one type of seed suddenly isn't available....
Howard Hughes Medical Institute
Using DNA to Explore Lizard Phylogeny
On the Caribbean islands, lizards expanded into different niches instead of competing for resources. Scholars discuss and learn from experts in a video how scientists prove the theory. They build phylogenetic trees based on appearances...
Howard Hughes Medical Institute
Lactose Intolerance: Fact or Fiction
Around the world, about 2/3 of adult humans are lactose intolerant. Scholars work in small groups to discuss a few statements about lactose intolerance. Then, they watch a video on the topic and readdress each statement. Whole-class...
Howard Hughes Medical Institute
Got Lactase? Blood Glucose Data Analysis
Many physicals include a blood glucose test, but what are doctors actually testing? Scholars graph and interpret blood glucose data, allowing them to observe the differences in lactase persistence and draw conclusions. They then connect...
Howard Hughes Medical Institute
Using Genetic Crosses to Analyze a Stickleback Trait
Two fish appear different, but how do scientists determine their genotypes? Scholars practice performing test crosses to determine the genotypes of fish given their phenotypes. They answer in-depth comprehension questions and complete...
Howard Hughes Medical Institute
Modeling the Regulatory Switches of the Pitx1 Gene in Stickleback Fish
Gene switches work similarly to light switches in controlling one feature of their environments. Scholars study the Pitx1 gene in a specific type of fish. They learn the different ways this switch controls various body parts and...
Howard Hughes Medical Institute
Mendelian Genetics, Probability, Pedigree, and Chi-Square Statistics
People with the sickle cell trait, but not sickle cell disease, find natural protection against malaria. Scholars consider various combinations of genotypes and environmental factors to determine if children might have sickle cell...
Howard Hughes Medical Institute
Reading Primary Sources: Darwin and Wallace
Take your classes back in time. Learners read real historical texts from both Darwin and Wallace as well as an announcement of their findings. Using guiding questions, they make inferences and draw conclusions from the information in the...
Howard Hughes Medical Institute
Look Who's Coming for Dinner: Selection by Predation
What happens when a new predator comes to town? Learners analyze an experiment that studies the effect of predation on selection. They use real data to draw conclusions about the impact a new predator has on a prey species.
Howard Hughes Medical Institute
Weighing the Evidence for a Mass Extinction: Part 1 – In the Ocean
Extinction events have happen throughout geologic history, but only five mass extinctions occurred over the last 4.5 billion years. Scholars view fossils from a layer of sediment during an extinction event and observe patterns to draw...
Howard Hughes Medical Institute
Explore Your Inner Animals
Human bodies prove evolution thanks to our genes, bones, and more. Learning about specific body parts and how they evolved from other species helps individuals better understand the transition species that helped us become who we are today.
Howard Hughes Medical Institute
Human Skin Color: Evidence for Selection
Skin color is controlled by at least six genes. Young scientists learn about skin colors through a documentary. They discuss the topics of pigment, natural selection, and vitamin D absorption. They apply their knowledge to higher order...
Howard Hughes Medical Institute
Visualizing Gene-Expression Patterns
How do genetics gurus know so much about gene expression? See traits materialize before your very eyes using a presentation with embedded simulations. Science scholars develop an understanding of the techniques used to follow the work of...
Howard Hughes Medical Institute
Natural Selection and the Evolution of Darwin's Finches
Darwin explained the connection between species of finches 150 years before scientists understood DNA. Technology and progressing science proved he was right, yet many struggle to understand how natural selection happens. Scholars use...
Howard Hughes Medical Institute
Comparative Anatomy of the Domestic Chicken
Are chickens and crocodiles really related? Young scientists compare the bone structure of current domestic chickens to other animals throughout evolution. This helps them understand the branches that separate crocodiles and birds as...
Next Generation Science Storylines
Why Don't Antibiotics Work Like They Used To?
Bacteria get more resistant to antibiotics every year. Learn the reason for this pattern and how scientists are addressing the problem in a six-week unit. Learners analyze different types of bacteria and their adaptations.