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Lesson Plan
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Children’s Hospital of Philadelphia

Discovery and Development of Vaccines

For Teachers 9th - 12th Standards
Stop the spread. Pupils work through two activities to gain an understanding of vaccines and immunity. Learners research different types of vaccines and how they are made and explore the advantages and disadvantages of them. Using a...
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Activity
Biology Corner

A Chromosome Study

For Teachers 9th - 12th Standards
Study groups based on sizes of pairs. Pupils use images of chromosomes to create an organized pattern grouped into pairs and organized on size called a karyotype. Scholars create a second karyotype that contains a genetic disorder and...
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Activity
Museum of Science

Strawberry DNA

For Teachers K - 6th Standards
Humans aren't the only ones with DNA—fruit has it too. Using a extraction solution, pupils pull the DNA out of a piece of fruit. Learners crush up a piece of fruit with the solution and filter out the solids. Scholars then add cold...
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Activity
National Academy of Sciences

Genetic Disease: Putting DNA to Work

For Teachers 7th - 12th Standards
Scientific knowledge of genetic information has grown quickly over the last decade. An interactive lesson has learners research the role of science and medicine in diagnosing and treating genetic disorders. They consider the job of the...
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Interactive
American Museum of Natural History

DNA Detective

For Students 6th - 12th Standards
Match up the DNA code. Pupils read the website from the American Museum of Natural History about how DNA can determine whether a skin is from a particular type of reptile. Using the same technique, learners match up products with the...
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Website
American Museum of Natural History

All About Cloning

For Students 6th - 12th Standards
Start seeing double. The American Museum of Natural History website provides pupils with information about Dolly, the cloned sheep. Learners find out the procedure used to create Dolly along with why scientists clone animals.
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Interactive
American Museum of Natural History

What's This? Frozen Tissue

For Students 6th - 12th Standards
Take a peek into thousands of frozen samples. Learners try to identify an image of a piece of frozen tissue. After choosing the correct answer, scholars find out more information about the American Museum of Natural History's Frozen...
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Website
American Museum of Natural History

What's the Big Idea About Genetics?

For Students 6th - 12th Standards
Here's a quick read on genetics. An engaging online resource provides six slides of information about genetics. Learners read about the meaning of genetics to information about DNA. They also learn about the study of genes and the...
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Interactive
American Museum of Natural History

What Do You Know About Genetics?

For Students 6th - 12th Standards
Just what do you know about genetics? The online resource contains 10 questions about genetics. Scholars work through the questions ranging from what DNA stands for to how much of human DNA is similar to that of a fruit fly. Scholars...
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Interactive
American Museum of Natural History

A Nature and Nurture Walk in Mendel Park

For Students 6th - 12th Standards
We are what we make of ourselves ... sometimes. Learners play a game to come up with the answer to a riddle. The game consists of determining whether different scenarios are due to nature or nature and nurture. With each correct answer,...
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eBook
BC Open Textbooks

Concepts of Biology – 1st Canadian Edition

For Students 9th - 12th Standards
How diverse are living things? Individuals explore topics such as cells as the foundation for life, cell division and genetics, molecular biology, and animal reproduction using an open resource Biology textbook. They learn key terms...
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Lesson Plan
Agriculture in the Classroom

Design 'Y'er Genes

For Teachers 9th - 12th Standards
How do changes in DNA affect an organism? Scholars explore chromosomes, genes, DNA, and mutations by modeling the DNA of a strawberry. They build a DNA model, then manipulate it to show how changing the genes transforms the strawberry...
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Activity
Howard Hughes Medical Institute

Pulse Chase Primer: The Meselson-Stahl Experiment

For Teachers 9th - 12th Standards
Experimental design can make or break an experiment. Young scholars analyze the pulse-chase analysis procedure by studying the Meselson-Stahl experiment. Using a video presentation, they discover how the pulse-chase analysis led to the...
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Activity
Howard Hughes Medical Institute

Mapping Genes to Traits in Dogs Using SNPs

For Teachers 9th - 12th Standards
Genetic analysis has gone to the dogs! Learners use real DNA information collected from dog saliva to study the relationship between genotypes and phenotypes. They analyze alleles to determine correlations to coat color, length, and...
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Activity
Howard Hughes Medical Institute

Pedigrees and the Inheritance of Lactose Intolerance

For Teachers 9th - 12th Standards
What, exactly, causes lactose intolerance? Scholars view a video describing a Finnish study that determined why some people are tolerant while others are intolerant. They then use the data from the study to reenact the experiment and...
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Activity
Howard Hughes Medical Institute

Milk—How Sweet Is It?

For Teachers 9th - 12th Standards
Have you ever wondered why some people are lactose intolerant? Participants test simulated patients in a hands-on lab activity to find out! They learn about lactose intolerance by performing an experiment, analyzing data, and drawing...
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Activity
Howard Hughes Medical Institute

Molecular Genetics of Color Mutations in Rock Pocket Mice

For Teachers 9th - 12th Standards
Can you identify mutations just by viewing DNA sequences? Scholars apply prior knowledge of DNA sequences to do just that in an engaging activity. They transcribe and translate genes, thus identifying the locations of mutations. Then,...
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Activity
Howard Hughes Medical Institute

Biochemistry and Cell Signaling Pathway of the Mc1r Gene

For Teachers 9th - 12th Standards
How do mice have so much fur color variation over generations? Scholars illustrate protein structures based on amino acid sequences. Then, they analyze the signaling pathway in different-colored mice populations. This allows them to...
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Activity
Howard Hughes Medical Institute

Natural Selection and Evolution of Rock Pocket Mouse Populations

For Teachers 9th - 12th Standards
Can evolution repeat itself? Scholars analyze amino acid data in two separate populations of mice. They learn that evolution repeats itself, but natural selection prefers some mutations over others in different environments. Analysis...
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Activity
Howard Hughes Medical Institute

The Molecular Evolution of Gene Birth and Death

For Teachers 9th - 12th Standards
More than 90 percent of humans' DNA doesn't code for anything! Scholars watch a presentation as they answer questions relating to gene mutations. They read details, watch videos, and view animations supporting the concepts. The questions...
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Activity
Howard Hughes Medical Institute

How Do Fibers Form?

For Teachers 9th - 12th Standards
The proteins inside a cell determine the shape of the cell. While most red blood cells have a circular shape, those with sickle cell take the shape of a sickle. This change in shape causes multiple issues in the system. Scholars solve...
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Activity
Howard Hughes Medical Institute

Population Genetics, Selection, and Evolution

For Teachers 9th - 12th Standards
The Hardy-Weinberg principle states that alleles and genotypes remain constant in the absence of evolutionary influences. Scholars complete a simple hands-on activity applying the Hardy-Weinberg principle to sample data. They observe how...
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Lesson Plan
Serendip

Genetic Engineering Challenge – How Can Scientists Develop a Type of Rice That Could Prevent Vitamin A Deficiency?

For Teachers 9th - 12th Standards
Brown rice contains vitamins B and E, while white rice lasts longer in storage. The availability of rice around the world makes it a great candidate for genetic engineering. Scholars apply their knowledge of genetic engineering to solve...
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Activity
Howard Hughes Medical Institute

Classroom Activities: Planaria Regeneration Activity

For Teachers 9th - 12th Standards
Observe a flatworm as it regenerates its own head. A laboratory exploration asks learners to cut a planaria worm at different locations and then observe it regenerate. Using data collected during the exploration, they make conclusions...