Howard Hughes Medical Institute
Genetic Mutations and Disease Interactive
Genetic mutations occur throughout life, from conception to old age, and the timing influences the severity. Young scientists learn about four different mutation times and the diseases that sometimes occur as a result. They observe the...
Curated OER
Genes, DNA, and Mutations
With paper DNA patterns, budding biologists model translation and base-pair substitution within sequences. Through these activities, they examine how mutations can result in genetic disorders. The modeling that occurs is an enlightening...
Biology Junction
Mutations
Are you a mutant? Learn about multiple types of mutations with a presentation to discover the answer. Both genes and chromosomes mutate at various points in their life cycles. Slides describe each type and the resulting impact on...
Curated OER
Mutations
After studying DNA replication and the genetics of inheritance, this slide show is useful for explaining specific mutations that can happen and result in an illness. Sickle cell anemia, and cystic fibrosis are explained on a genetic...
Concord Consortium
Mutations
Are some mutations more damaging than others? An engaging simulation encourages scholars to alter DNA through insertion, deletion, and substitution. It then forms resulting amino acids—or not—and the resulting protein—or not—depending on...
Howard Hughes Medical Institute
Molecular Genetics of Color Mutations in Rock Pocket Mice
Can you identify mutations just by viewing DNA sequences? Scholars apply prior knowledge of DNA sequences to do just that in an engaging activity. They transcribe and translate genes, thus identifying the locations of mutations. Then,...
Curated OER
Mutations
The basics of mutation types and some potential effects of those are described and diagrammed here. Each detail is very clear and includes the labels and translation change exhibited. A great slideshow to expand on DNA replication issues.
Virginia Department of Education
Genetic Variation and Mutations
Young scientists demonstrate their creativity while completing several activities, to assess genetic variations and mutations. Instructors provide a list of options and scientists choose to write a comic strip, create a book, construct a...
Cold Spring Harbor Laboratory
Mutations Are Changes in Genetic Information
A red delicious apple tree with a simple mutation means we now benefit from the existence of golden delicious apples. Learn how simple mutations change genetic information in DNA sequences. Using biographies, videos, and animations,...
Serendip
The Molecular Biology of Mutations and Muscular Dystrophy
Different types of mutations cause unique types and degrees of muscular dystrophy. Scholars learn about the types of mutations and the impact on the body. They compare the location of the mutations and draw conclusions about how it is...
Curated OER
Allele and Phenotype Frequencies in Rock Pocket Mouse Populations
In the deserts of Arizona and New Mexico, some tiny creatures show just how quickly natural selection can turn a mutation into an advantageous adaptation. Watch a video about rock pocket mice, who show that one small change can make all...
Serendip
Evolution of Fur Color in Mice – Mutation, Environment and Natural Selection
Most species of animals include a variety of fur or hair color, but why? Scholars watch a video about a changing environment for mice. As the rocks around them change hues, different colors of mice begin to thrive. Discussion questions...
Curated OER
Monstrous Mutations
Students investigate mutations and simulate their mutation while trying to collect food. In this mutations lesson plan, students pick an identified mutation out of a paper bag. They simulate their mutation while trying to collect food...
Curated OER
DNA, RNA, Protein Synthesis, & Mutation
In this biology worksheet, students identify and label the diagram shown by stating what each part of the diagram represents on the line. Then they use the DNA strand as the original strand and complete the data table. Students also...
Curated OER
Selection and Variation in the Egyptian Origami Bird
Using origami paper birds, your biology class will experiment with mutations and natural selection to determine wing position, length, and width. It would be helpful to provide a worksheet to go with the activity that includes a...
Curated OER
How Mutations Lead to Changes in Cell Structure and Function
High schoolers investigate how mutations lead to changes in cell structure and function. They construct an oligonucleotide, identify a protein sequence, design a step-by-step mechanism of how they think cells repair damaged DNA, and...
Curated OER
The Clark Family Story: Tracing the Cause of Hemophilia
Ms. Strohfeldt did not omit anything when she designed this comprehensive lesson plan on DNA mutation and sex-linked traits. Begin with a pretest as an anticipatory set. Read a case history of the Clark family and the occurrence of...
Science 4 Inquiry
"Something Old, Something New..."
Young scientists learn about DNA replication through a video and model creation. They answer analysis questions before exploring the role of mutations and then complete a summative assessment.
Curated OER
Mutations and Cancer
Students study how cancer cells mutate and affect cell division. In this investigative lesson students view a PowerPoint presentation learn the seven warning signs of cancer.
Curated OER
AP: Chapter 19: Control of Eukaryotic Genome
When your AP biology class is studying DNA and genomes, this worksheet will provide a detailed review. On the first page are diagrams and matching SEM (scanning electron microscope) images of different levels of DNA packing to be...
Curated OER
Genetics PowerPoint
If mom is bald, will her babies be bald? Here is a practical presentation that can answer that question. Viewers can take notes on the difference between dominant and recessive genes, mutations, and heritability. A large portion of the...
Curated OER
Mutations--Preexisting or Acquired?
Students explore the reasoning and experimental approaches to mutations. They expose a culture of E. coli to virulent bacteriophage and observe whether mutations of the cells existed previously or if the bacteria mutated as a response...
Curated OER
Mutations--Preexisting or Acquired?
Students state the controls and variables of the Newcombe spread experiment. They state a hypothesis for the Newcombe spread experiment. Students distinguish between the characteristics of a preexisting mutations and those of an...
Curated OER
Mutations and Genetic Change
In this genetic mutations worksheet, students compare and contrast different types of mutations including point mutations, silent mutations, and frameshift mutations. This worksheet has 5 matching, 4 fill in the blank, and 3 short answer...
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