Curated OER
Tracing Genetic Ancestry Using DNA Microarrays
High school learners read and discuss an article about genetic ancestry and genetic ancestry testing. They complete a paper and pencil activity that mimics the function of a DNA microarray and consider the ethics of genetic testing in...
Concord Consortium
Mutations
Are some mutations more damaging than others? An engaging simulation encourages scholars to alter DNA through insertion, deletion, and substitution. It then forms resulting amino acids—or not—and the resulting protein—or not—depending on...
Curated OER
DNA Mutations
In this DNA mutations worksheet, students translate DNA sequences in amino acid sequences and determine if the mutation is harmful or not. This worksheet is a graphic organizer.
Curated OER
Genes, DNA, and Mutations
With paper DNA patterns, budding biologists model translation and base-pair substitution within sequences. Through these activities, they examine how mutations can result in genetic disorders. The modeling that occurs is an enlightening...
Biology Junction
Mutations
Are you a mutant? Learn about multiple types of mutations with a presentation to discover the answer. Both genes and chromosomes mutate at various points in their life cycles. Slides describe each type and the resulting impact on...
Curated OER
DNA Cut and Paste Activity
Here is a cut and paste activity worksheet designed for older students. They fill in the blank with information about the composition of DNA, then create a DNA strand with its complimentary nucleotide chain.
Curated OER
Mutations
After studying DNA replication and the genetics of inheritance, this slide show is useful for explaining specific mutations that can happen and result in an illness. Sickle cell anemia, and cystic fibrosis are explained on a genetic...
Curated OER
DNA, RNA, Protein Synthesis, & Mutation
In this biology worksheet, students identify and label the diagram shown by stating what each part of the diagram represents on the line. Then they use the DNA strand as the original strand and complete the data table. Students also...
Curated OER
How Mutations Lead to Changes in Cell Structure and Function
High schoolers investigate how mutations lead to changes in cell structure and function. They construct an oligonucleotide, identify a protein sequence, design a step-by-step mechanism of how they think cells repair damaged DNA, and...
Curated OER
The Clark Family Story: Tracing the Cause of Hemophilia
Ms. Strohfeldt did not omit anything when she designed this comprehensive lesson plan on DNA mutation and sex-linked traits. Begin with a pretest as an anticipatory set. Read a case history of the Clark family and the occurrence of...
CK-12 Foundation
Transcription of DNA to RNA: Making mRNA
Transcription means a written copy but how can DNA write a message? The video explains transcription and translation as they relate to DNA and RNA. Then in the interactive, scholars practice base pairing and answer analysis questions...
Howard Hughes Medical Institute
Molecular Genetics of Color Mutations in Rock Pocket Mice
Can you identify mutations just by viewing DNA sequences? Scholars apply prior knowledge of DNA sequences to do just that in an engaging activity. They transcribe and translate genes, thus identifying the locations of mutations. Then,...
Curated OER
DNA Replication
Students create a model of DNA and simulate replication with their models in an activity that uses licorice, colored marshmallows, and toothpicks. Students also label a diagram of replication and indicate major parts of the DNA molecule.
Cold Spring Harbor Laboratory
Mutations Are Changes in Genetic Information
A red delicious apple tree with a simple mutation means we now benefit from the existence of golden delicious apples. Learn how simple mutations change genetic information in DNA sequences. Using biographies, videos, and animations,...
Curated OER
Mutations
The basics of mutation types and some potential effects of those are described and diagrammed here. Each detail is very clear and includes the labels and translation change exhibited. A great slideshow to expand on DNA replication issues.
Serendip
UV, Mutations, and DNA Repair
How effective are cells at repairing UV damage? An inquiry-based lesson has learners experiment with organism by exposing them to various levels of UV light and then examining their DNA after a period of time. Pupils test different...
Virginia Department of Education
Genetic Variation and Mutations
Young scientists demonstrate their creativity while completing several activities, to assess genetic variations and mutations. Instructors provide a list of options and scientists choose to write a comic strip, create a book, construct a...
Cold Spring Harbor Laboratory
Some Types of Mutations Are Automatically Repaired
Does natural light damage or repair DNA? Learn the answer discover the scientists who researched the topic with an online interactive. Scholars read through an online animation presenting the content at their own pace. Then, they read...
Serendip
The Molecular Biology of Mutations and Muscular Dystrophy
Different types of mutations cause unique types and degrees of muscular dystrophy. Scholars learn about the types of mutations and the impact on the body. They compare the location of the mutations and draw conclusions about how it is...
Howard Hughes Medical Institute
Creating Phylogenetic Trees from DNA Sequences
How closely are animals related? Check their phylogenetic trees! The use of DNA sequencing altered our understanding of these relationships. Individuals explore and gain a better understanding of how scientists sort, align, and determine...
Howard Hughes Medical Institute
Virochip DNA Microarray
Virochips detect and identify viruses at a higher rate than other tests. Show young scientists how Virochips work to identify existing viruses. They analyze results demonstrating mutations or the evolution of viruses and view videos...
Howard Hughes Medical Institute
The Making of the Fittest: The Birth and Death of Genes
Adaptations must be made as environments change. This fabulous presentation features Icelandic icefish, a transparent, scaleless specimen that even has colorless blood. Genetics and adaptations concepts are explored as scientists study...
Howard Hughes Medical Institute
Got Lactase? The Co-Evolution of Genes and Culture
Does the human body evolve as quickly as human culture? With a stellar 15-minute video, explore the trait of lactose intolerance. Only about 1/3 of human adults seem to still have the enzyme lactase and therefore, the ability to digest...
Curated OER
Regents High School Examination: Living Environment 2005
The 2005 version of the Regents High School Examination in the area of ecology is as comprehensive as previous years' exams. It consists of 40 multiple choice questions on everything from the structure of DNA to the interactions within...
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