Curated OER
Tracing Genetic Ancestry Using DNA Microarrays
High school learners read and discuss an article about genetic ancestry and genetic ancestry testing. They complete a paper and pencil activity that mimics the function of a DNA microarray and consider the ethics of genetic testing in...
Virginia Department of Education
Genetic Variation and Mutations
Young scientists demonstrate their creativity while completing several activities, to assess genetic variations and mutations. Instructors provide a list of options and scientists choose to write a comic strip, create a book, construct a...
Curated OER
Genes, DNA, and Mutations
With paper DNA patterns, budding biologists model translation and base-pair substitution within sequences. Through these activities, they examine how mutations can result in genetic disorders. The modeling that occurs is an enlightening...
Curated OER
DNA Cut and Paste Activity
Here is a cut and paste activity worksheet designed for older students. They fill in the blank with information about the composition of DNA, then create a DNA strand with its complimentary nucleotide chain.
Howard Hughes Medical Institute
The Making of the Fittest: The Birth and Death of Genes
Adaptations must be made as environments change. This fabulous presentation features Icelandic icefish, a transparent, scaleless specimen that even has colorless blood. Genetics and adaptations concepts are explored as scientists study...
Howard Hughes Medical Institute
Molecular Genetics of Color Mutations in Rock Pocket Mice
Can you identify mutations just by viewing DNA sequences? Scholars apply prior knowledge of DNA sequences to do just that in an engaging activity. They transcribe and translate genes, thus identifying the locations of mutations. Then,...
Serendip
UV, Mutations, and DNA Repair
How effective are cells at repairing UV damage? An inquiry-based lesson has learners experiment with organism by exposing them to various levels of UV light and then examining their DNA after a period of time. Pupils test different...
Curated OER
The Clark Family Story: Tracing the Cause of Hemophilia
Ms. Strohfeldt did not omit anything when she designed this comprehensive lesson plan on DNA mutation and sex-linked traits. Begin with a pretest as an anticipatory set. Read a case history of the Clark family and the occurrence of...
Curated OER
DNA Replication
Students create a model of DNA and simulate replication with their models in an activity that uses licorice, colored marshmallows, and toothpicks. Students also label a diagram of replication and indicate major parts of the DNA molecule.
Howard Hughes Medical Institute
Got Lactase? The Co-Evolution of Genes and Culture
Does the human body evolve as quickly as human culture? With a stellar 15-minute video, explore the trait of lactose intolerance. Only about 1/3 of human adults seem to still have the enzyme lactase and therefore, the ability to digest...
Curated OER
Mitosis Cookies Activity
Reward biology learners for working hard in their mitosis lesson with a sweet snack at the end! They begin by twisting apart creme-filled cookies and using the icing as a cytoplasm. Colored candy sprinkles make up chromosome pairs, which...
Serendip
The Molecular Biology of Mutations and Muscular Dystrophy
Different types of mutations cause unique types and degrees of muscular dystrophy. Scholars learn about the types of mutations and the impact on the body. They compare the location of the mutations and draw conclusions about how it is...
Curated OER
Cell Wall Recipe: A Lesson on Biofuels
Biotech engineers discover that changes in the DNA code for cell wall formation can help create crops better suited for biofuel production. They extract DNA from wheat germ. They decode paper strips with codes and relate the activity to...
Agriculture in the Classroom
Design 'Y'er Genes
How do changes in DNA affect an organism? Scholars explore chromosomes, genes, DNA, and mutations by modeling the DNA of a strawberry. They build a DNA model, then manipulate it to show how changing the genes transforms the strawberry...
Curated OER
Constructing a Phylogenetic Tree Using DNA Sequence Data
Students analyze DNA sequence differences between organisms in order to establish a reasonable picture of the evolutionary relationships between them. They take the role of molecular biologists and make genetic changes and constructing...
Curated OER
DNA Code
Students synthesize information gathered from the web on reading the DNA code. In this upper-level biology activity, students use an online resource to gain information about DNA codes and then create posters on what they have learned....
Curated OER
Mutations and Cancer
Students study how cancer cells mutate and affect cell division. In this investigative lesson students view a PowerPoint presentation learn the seven warning signs of cancer.
Curated OER
Regulation of Cell Division
Cell division and all the biological aspects of activation and chemical signals are detailed here. Cyclin, G phases, cell growth, and cancer checkpoint control systems are explained and the triggers listed. The slides are very clear and...
Howard Hughes Medical Institute
Ebola: Disease Detectives
How did the Ebola virus first infect humans? Young virologists examine genetic sequences from the 2014 Sierra Leone outbreak to find similarities during a riveting activity. Following similar methods used by MIT and Harvard, partners...
Curated OER
Creative Ways To Teach Evolutionary Concepts
Research how DNA, the genetic blueprint of living organisms, plays an essential role in the continuity of life. High schoolers will summarize how their influence may very well effect the destiny of the population from one generation to...
Howard Hughes Medical Institute
The Molecular Evolution of Gene Birth and Death
More than 90 percent of humans' DNA doesn't code for anything! Scholars watch a presentation as they answer questions relating to gene mutations. They read details, watch videos, and view animations supporting the concepts. The questions...
Curated OER
How Things Go Wrong
Students identify where mutations might occur and examine what effect those mutations will have through class discussion of DNA replication and cell division. Students then differentiate between mutations that affect individuals and...
Kenan Fellows
Unit 3: Genetic Variation
What happens when genes change? Junior genetic investigators examine the effects of mutation in the third unit of a four-part Biotechnology series. Individuals discover the types of mutations through a series of PowerPoints, then partner...
Cold Spring Harbor Laboratory
Master Genes Control Basic Body Plans
Have you ever been so tired you missed a major announcement? Eric Wieschaus woke to a call explaining he won the Nobel Prize, but he thought it was just a dream until Christiane Nusslein-Volhard, a co-winner, explained it to him later...