Activity
Howard Hughes Medical Institute

Tracking Genetically Modified Mosquitoes

For Teachers 9th - 12th Standards
What's that buzzing in your ear? An insightful lesson about genetically modified mosquitoes! Partnered pupils explore the creation, release, and monitoring of mosquitoes designed to reduce the mosquito population. After watching a video,...
Activity
Howard Hughes Medical Institute

Natural Selection and Evolution of Rock Pocket Mouse Populations

For Teachers 9th - 12th Standards
Can evolution repeat itself? Scholars analyze amino acid data in two separate populations of mice. They learn that evolution repeats itself, but natural selection prefers some mutations over others in different environments. Analysis...
Activity
Howard Hughes Medical Institute

Population Genetics, Selection, and Evolution

For Teachers 9th - 12th Standards
The Hardy-Weinberg principle states that alleles and genotypes remain constant in the absence of evolutionary influences. Scholars complete a simple hands-on activity applying the Hardy-Weinberg principle to sample data. They observe how...
Activity
Howard Hughes Medical Institute

Color Variation Over Time in Rock Pocket Mouse Populations

For Teachers 9th - 12th Standards
While many mutations are neutral, those that appear advantageous increase in frequency in a population. Scholars use illustrations to make predictions about populations of mice. They follow it up with a video to confirm or refute their...
Activity
Howard Hughes Medical Institute

Color Variation Over Time in Rock Pocket Mouse Populations

For Teachers 9th - 12th Standards
Simple characteristic changes can have a significant impact on species survival. A hands-on activity has learners investigate the color variation in pocket mouse populations in different environments. They connect the timing and number...
Lesson Plan
Curated OER

The Effect of Natural Selection on Genes, Traits and Individuals

For Teachers 9th - 12th Standards
Rotating through five stations, evolutionary biologists explore the question of how changes in DNA facilitate the changes in a population over time. High-quality, colorful cards of animals, skeletons, skulls, and DNA sequences can all be...
Activity
Howard Hughes Medical Institute

Zebrafish and Skin Color

For Teachers 9th - Higher Ed
You may not know if that zebrafish in your fish tank is a model citizen—but it is definitely a model organism! What can we learn about ourselves from a tiny zebrafish? Discover more about the polygenic trait of skin color through a...
Activity
Howard Hughes Medical Institute

Understanding Variation

For Teachers 9th - Higher Ed Standards
Does where we live influence how our bodies express genetic traits? Explore variation in human skin color with an activity that incorporate video and hands-on learning. Individuals model the relationship between phenotypes and genotypes,...
Lesson Plan
Serendip

Golden Rice – Evaluating the Pros and Cons

For Teachers 9th - 12th Standards
More than half the world's population eats rice as a daily staple ... imagine if that rice could prevent illness. Scientists genetically engineered rice to include vitamin A for just that purpose. However, room for debate still exists....
Activity
Howard Hughes Medical Institute

Biochemistry and Cell Signaling Pathway of the Mc1r Gene

For Teachers 9th - 12th Standards
How do mice have so much fur color variation over generations? Scholars illustrate protein structures based on amino acid sequences. Then, they analyze the signaling pathway in different-colored mice populations. This allows them to...
Activity
Howard Hughes Medical Institute

Got Lactase? Blood Glucose Data Analysis

For Teachers 9th - 12th Standards
Many physicals include a blood glucose test, but what are doctors actually testing? Scholars graph and interpret blood glucose data, allowing them to observe the differences in lactase persistence and draw conclusions. They then connect...
Activity
Howard Hughes Medical Institute

Developing an Explanation for Mouse Fur Color

For Teachers 7th - 12th Standards
Whether or not you think mice are nice, you'll love the colorful activity! Scholars examine evidence for evolution in the rock pocket mouse through video, discussion, and collaborative work. Learners watch a video regarding variation in...
Activity
Howard Hughes Medical Institute

Lactase Persistence: Evidence for Selection

For Teachers 9th - 12th Standards
What's the link between lactase persistence and dairy farming? Biology scholars analyze data to find evidence of the connection, then relate this to human adaptation. Working individually and in small groups, learners view short video...
Activity
Howard Hughes Medical Institute

Patterns in the Distribution of Lactase Persistence

For Teachers 9th - 12th Standards
We all drink milk as babies, so why can't we all drink it as adults? Examine the trend in lactase production on the world-wide scale as science scholars analyze and interpret data. Groups create pie charts from the data, place them on a...
Lesson Plan
Serendip

UV, Mutations, and DNA Repair

For Teachers 9th - 12th
How effective are cells at repairing UV damage? An inquiry-based activity has learners experiment with organism by exposing them to various levels of UV light and then examining their DNA after a period of time. Pupils test different...
Activity
Howard Hughes Medical Institute

Measuring Biodiversity in Gorongosa

For Teachers 9th - 12th
Take your biology class' understanding of biodiversity to a whole new level! Ecology scholars use data to calculate three different diversity indices based on the organisms in the Gorongosa National Park. The four-part activity uses an...
Lesson Plan14:52
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Howard Hughes Medical Institute

The Making of the Fittest: Got Lactase? The Co-evolution of Genes and Culture

For Teachers 8th - Higher Ed Standards
Got milk? Only two cultures have had it long enough to develop the tolerance of lactose as an adult. Learn how the responsible genes evolved along with the cultures that have been consuming milk. This rich film is supplied with a few...
Activity
Howard Hughes Medical Institute

Natural Selection and the Evolution of Darwin's Finches

For Teachers 6th - 12th Standards
Darwin explained the connection between species of finches 150 years before scientists understood DNA. Technology and progressing science proved he was right, yet many struggle to understand how natural selection happens. Scholars use...
Activity
Howard Hughes Medical Institute

Stickleback Evolution Virtual Lab

For Students 9th - 12th Standards
How quickly do animals evolve? Can comparing different samples of the same fossil answer timeline questions? Scholars use virtual labs to examine fossils and learn about stickleback evolution. They compare pelvic morphology in lakes...
Activity
National Health Museum

Access Excellence: Hardy Weinberg Equilibrium

For Students 9th - 10th
This site explores what Hardy-Weinberg Equilibrium is, and how teachers can explore this topic in their classrooms. Content includes background information on this topic, as well as numerous learning activities.
Activity
Texas Instruments

Texas Instruments: Numb3 Rs: All in the Family

For Teachers 9th - 10th
Based off of the hit television show NUMB3RS, this lesson shows students the scientific reasoning behind the societal taboo of incest. Students complete a Punnett square to determine the chances of an offspring inheriting two recessive...
Activity
Howard Hughes Medical Institute

Hhmi: Biointeractive: Schooling Behavior Stickleback Fish From Different Habitats

For Students 9th - 10th
A team of scientists studied the schooling behavior of threespine stickleback fish by experimentally testing how individual fish responded to an artificial fish school model.

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