Howard Hughes Medical Institute
The Making of the Fittest: Natural Selection and Adaptation
The pocket mouse can be light brown like the sands of the desert, or dark brown like the volcanic lava flows that are interspersed throughout New Mexico's Valley of Fire. It seems that predators have weeded out light colored mice in this...
University of Pennsylvania
Evolution by Natural Selection
A diagram, data table, and reading passage top this resource. Through it, biology beginners are introduced to the concept of natural selection. They answer some questions and then participate in a simulation using fabric as a habitat and...
Howard Hughes Medical Institute
Icefish Adaptations
What adaptations exist in order for icefish to survive the subfreezing temperatures of the Antarctic Ocean? Middle and high schoolers can find out through watching a related 13-minute video and performing a simple investigation to...
Howard Hughes Medical Institute
Natural Selection and Evolution of Rock Pocket Mouse Populations
Can evolution repeat itself? Scholars analyze amino acid data in two separate populations of mice. They learn that evolution repeats itself, but natural selection prefers some mutations over others in different environments. Analysis...
Serendip
Evolution and Adaptations
Survival of the fittest isn't just for the movies! A five-part lesson plan explores several different species with known adaptations and analyzes them for their survival strategies. Using both video and research data, scholars draw...
Howard Hughes Medical Institute
Stickleback Evolution Virtual Lab
How quickly do animals evolve? Can comparing different samples of the same fossil answer timeline questions? Scholars use virtual labs to examine fossils and learn about stickleback evolution. They compare pelvic morphology in lakes...
Howard Hughes Medical Institute
Natural Selection and the Evolution of Darwin's Finches
Darwin explained the connection between species of finches 150 years before scientists understood DNA. Technology and progressing science proved he was right, yet many struggle to understand how natural selection happens. Scholars use...
Howard Hughes Medical Institute
Icefish Blood Adaptations: Antifreeze Proteins
Ever wonder how fish survive in freezing cold water—especially Antarctic waters? Some fish have an adaptation that lowers the freezing point of their life fluids. Learners model these adaptations in two lab explorations. The first...
Curated OER
The Effect of Natural Selection on Genes, Traits and Individuals
Rotating through five stations, evolutionary biologists explore the question of how changes in DNA facilitate the changes in a population over time. High-quality, colorful cards of animals, skeletons, skulls, and DNA sequences can all be...
Howard Hughes Medical Institute
The Making of the Fittest: Natural Selection in Humans
Sickle cell disease only occurs when both parents contribute the trait, and mostly in those of African descent. Where did it come from? How did it evolve? Tony Allison, a molecular biologist, noticed a connection between sickle cell and...
Howard Hughes Medical Institute
Icefish Blood Adaptations: Viscosity
Most fish freeze to death when the water is too cold, yet some fish live in the Southern Ocean where the water is often below freezing. Scholars use two models representing the blood from most fish versus the blood from Antarctic fish....
Howard Hughes Medical Institute
Using DNA to Explore Lizard Phylogeny
In a fun and interactive two-day lesson, learners sort anole lizard pictures by appearance. Next, they watch a video about the anoles and re-sort based on the information in the video. In addition to physical characteristics, budding...
Howard Hughes Medical Institute
The Making of the Fittest: Evolving Switches, Evolving Bodies
How did the stickleback fish, which was once ocean bound, evolve to be able to persist in freshwater lakes? Hear from the scientists who identified the genes and related switches that allowed these survivors to adapt. In addition to the...
Howard Hughes Medical Institute
Lactase Persistence: Evidence for Selection
What's the link between lactase persistence and dairy farming? Biology scholars analyze data to find evidence of the connection, then relate this to human adaptation. Working individually and in small groups, learners view short video...
Howard Hughes Medical Institute
Lactose Intolerance: Fact or Fiction
Around the world, about 2/3 of adult humans are lactose intolerant. Scholars work in small groups to discuss a few statements about lactose intolerance. Then, they watch a video on the topic and readdress each statement. Whole-class...
Howard Hughes Medical Institute
Reading Primary Sources: Darwin and Wallace
Take your classes back in time. Learners read real historical texts from both Darwin and Wallace as well as an announcement of their findings. Using guiding questions, they make inferences and draw conclusions from the information in the...
Howard Hughes Medical Institute
Developing an Explanation for Mouse Fur Color
Whether or not you think mice are nice, you'll love the colorful activity! Scholars examine evidence for evolution in the rock pocket mouse through video, discussion, and collaborative work. Learners watch a video regarding variation in...
Howard Hughes Medical Institute
Living Dinosaurs: Fact or Fiction?
Are birds descendants of dinosaurs? Learners consider the question as they watch an informative video comparing fossil records of dinosaurs with current species. Following the video, groups ponder the evidence to draw conclusions about...
Howard Hughes Medical Institute
The Making of the Fittest: The Birth and Death of Genes
After watching an engaging 13-minute video about the colorless blood of icefish, future ichthyologists examine icefish blood and non-icefish blood (blood samples are simulated with Karo syrup mixtures) to determine advantages of...
Howard Hughes Medical Institute
Modeling the Regulatory Switches of the Pitx1 Gene in Stickleback Fish
Gene switches work similarly to light switches in controlling one feature of their environments. Scholars study the Pitx1 gene in a specific type of fish. They learn the different ways this switch controls various body parts and...
Howard Hughes Medical Institute
Using DNA to Explore Lizard Phylogeny
On the Caribbean islands, lizards expanded into different niches instead of competing for resources. Scholars discuss and learn from experts in a video how scientists prove the theory. They build phylogenetic trees based on appearances...
Howard Hughes Medical Institute
Beaks as Tools: Selective Advantage in Changing Environments
How does nature select some adaptations over others? Scholars experiment picking up seeds with two different types of tools simulating beaks. After practicing, they experience a drought where one type of seed suddenly isn't available....
Discovery Education
The Time of Our Life
Mammals are some of the newest organisms to appear on Earth. Young scholars complete an activity that results in a timeline showing the appearance of different types of living organisms. Provided with a list that spans from prokaryotes...
Howard Hughes Medical Institute
Zebrafish and Skin Color
You may not know if that zebrafish in your fish tank is a model citizen—but it is definitely a model organism! What can we learn about ourselves from a tiny zebrafish? Discover more about the polygenic trait of skin color through a...