Howard Hughes Medical Institute
A Lesson on the Nature of Science
If you are looking for a great way to present natural selection in humans, look no further. This handout is intended to accompany the 14-minute video The Making of the Fittest: Natural Selection in Humans, which can be found on the...
California Academy of Science
Color Vision Genetics Evolution Simulation
At one point, all mammals carried only two color receptors, but now most humans carry three. An informative presentation and hands-on activity demonstrate how this evolved through genetics. By participating in the activity, pupils...
Howard Hughes Medical Institute
The Making of the Fittest: Natural Selection and Adaptation
The pocket mouse can be light brown like the sands of the desert, or dark brown like the volcanic lava flows that are interspersed throughout New Mexico's Valley of Fire. It seems that predators have weeded out light colored mice in this...
Howard Hughes Medical Institute
The Making of the Fittest: Evolving Switches, Evolving Bodies
How did the stickleback fish, which was once ocean bound, evolve to be able to persist in freshwater lakes? Hear from the scientists who identified the genes and related switches that allowed these survivors to adapt. In addition to the...
Howard Hughes Medical Institute
The Making of the Fittest: Got Lactase? The Co-evolution of Genes and Culture
Got milk? Only two cultures have had it long enough to develop the tolerance of lactose as an adult. Learn how the responsible genes evolved along with the cultures that have been consuming milk. This rich film is supplied with a few...
Howard Hughes Medical Institute
The Making of the Fittest: The Birth and Death of Genes
Adaptations must be made as environments change. This fabulous presentation features Icelandic icefish, a transparent, scaleless specimen that even has colorless blood. Genetics and adaptations concepts are explored as scientists study...
Howard Hughes Medical Institute
Natural Selection and the Evolution of Darwin's Finches
Darwin explained the connection between species of finches 150 years before scientists understood DNA. Technology and progressing science proved he was right, yet many struggle to understand how natural selection happens. Scholars use...
Curated OER
The Effect of Natural Selection on Genes, Traits and Individuals
Rotating through five stations, evolutionary biologists explore the question of how changes in DNA facilitate the changes in a population over time. High-quality, colorful cards of animals, skeletons, skulls, and DNA sequences can all be...
Howard Hughes Medical Institute
Stalking the Genetic Basis of a Trait
Need an a-maize-ing lesson to show your class how regulatory genes work? If you use the well-written resource, they'll be all ears! Biology scholars discover the gene responsible for the evolution of the modern-day corn plant through a...
Curated OER
Comparing Theories: Lamarck and Darwin
Students compare the evolution theories of Lamarck and Darwin. They use self-assessment and a video to increase their knowledge of evolution theories. They research questions and present them to the class.
Howard Hughes Medical Institute
Got Lactase? The Co-Evolution of Genes and Culture
Does the human body evolve as quickly as human culture? With a stellar 15-minute video, explore the trait of lactose intolerance. Only about 1/3 of human adults seem to still have the enzyme lactase and therefore, the ability to digest...
Virginia Department of Education 
Mendelian Genetics
How did Mendel know which pea plants would demonstrate certain characteristics? Pupils explore the answer this question, among others, as they complete Punnet squares, research dominant and recessive traits, and explore hereditary...
Biology Junction
Population Genetics
Genetic variation shows the health of a population, yet cheetahs show very little variation over that last 10,000 years. Scholars learn the importance of genetic variation in populations after viewing an informative presentation. It...
Cold Spring Harbor Laboratory
Some Types of Mutations Are Automatically Repaired
Does natural light damage or repair DNA? Learn the answer discover the scientists who researched the topic with an online interactive. Scholars read through an online animation presenting the content at their own pace. Then, they read...
Field Museum
The Case of Darwin's Finches
One of the most striking pieces of evidence for Darwin's Evolution of Species was his observations of finches and how their beaks differed from island to island, depending on their primary food sources. So what would happen to the theory...
Howard Hughes Medical Institute
Natural Selection and Evolution of Rock Pocket Mouse Populations
Can evolution repeat itself? Scholars analyze amino acid data in two separate populations of mice. They learn that evolution repeats itself, but natural selection prefers some mutations over others in different environments. Analysis...
Virginia Department of Education 
Evidence of Evolution
What an impression fossils make! In this activity, aspiring paleontologists view fossils and construct a timeline to further understand how the lack of natural adaptation caused historical organisms to become extinct. While they...
Howard Hughes Medical Institute
Patterns in the Distribution of Lactase Persistence
We all drink milk as babies, so why can't we all drink it as adults? Examine the trend in lactase production on the world-wide scale as science scholars analyze and interpret data. Groups create pie charts from the data, place them on a...
Curated OER
Evolution of the Virus: Teaching Macroevolution Through Microevolution
Students describe the anatomy of a virus. In this biology instructional activity, students compare and contrast the characteristics of bacteria and viruses. They discover the genetic adaptations of viruses over time.
Curated OER
Natural Selection Day 1
Young scholars define the concept of classification.  In groups, they categorize a series of objects into categories they identify.  As a class, they participate in a variety of activities to examine the concept of natural selection.  To...
University of California
Artificially Selecting Dogs
Selective breeding has resulted in some novel and beautiful or useful dogs over the years. Using the American Foxhound as an example, genetics learners find out how and why they came about. Then, in small groups, they select breeds to...
Howard Hughes Medical Institute
Survival of the Fittest - Variations in the Clam Species Clamys sweetus
It's not often that you come across a clever laboratory activity that is both imaginative and comprehensive! Using M&M's and Reese's peanut butter candies to represent two different clam species, young biologists test for "relative...
Howard Hughes Medical Institute
Mendelian Genetics, Probability, Pedigree, and Chi-Square Statistics
People with the sickle cell trait, but not sickle cell disease, find natural protection against malaria. Scholars consider various combinations of genotypes and environmental factors to determine if children might have sickle cell...
Serendip
Evolution of Fur Color in Mice – Mutation, Environment and Natural Selection
Most species of animals include a variety of fur or hair color, but why? Scholars watch a video about a changing environment for mice. As the rocks around them change hues, different colors of mice begin to thrive. Discussion questions...