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Serendip
DNA Structure, Function and Replication
Before a cell replicates, its DNA must replicate. Take advantage of a hands-on guided lesson to teach budding scientists how this happens. Using a set of nucleotide cards, learners become the DNA and work to create matching strands...
Howard Hughes Medical Institute
Viral DNA Integration
How do viruses hijack our cells to produce more viral particles? Junior immunologists model how viral RNA integrates into a host cell's DNA using pop beads and use interactive tools to explore a virus' genome. The teacher's guide...
Serendip
DNA
Get up close and personal with DNA! A two-part hands-on activity has learners extract DNA from a small organism and then their own cheek cells. Scholars then explore DNA replication using questions to guide their analyses.
Howard Hughes Medical Institute
Viral DNA Integration
How do reverse transcriptase inhibitors work? Young virologists examine the function of azidothymidine, a drug doctors use to treat HIV patients, during a hands-on modeling activity. Groups create a strand of DNA from an HIV RNA strand...
Howard Hughes Medical Institute
Virus Hunters: Epidemiology of Nipah Virus
Who actually goes looking for a virus? Expose your class to the high-stakes life of an epidemiologist on the trail of the Nipah virus. Pupils engage in a short video, then examine how scientists predict, model, and find the source of...
Howard Hughes Medical Institute
Understanding Variation
Does where we live influence how our bodies express genetic traits? Explore variation in human skin color with an activity that incorporate video and hands-on learning. Individuals model the relationship between phenotypes and genotypes,...
Serendip
From Gene to Protein via Transcription and Translation
DNA carries the codes for creating just the right protein. A well-designed lesson leads pupils through the process from start to finish and everywhere in between. Guiding questions with supporting video help scholars understand the...
Howard Hughes Medical Institute
Zebrafish and Skin Color
You may not know if that zebrafish in your fish tank is a model citizen—but it is definitely a model organism! What can we learn about ourselves from a tiny zebrafish? Discover more about the polygenic trait of skin color through a...
Howard Hughes Medical Institute
Natural Selection and the Evolution of Darwin's Finches
Darwin explained the connection between species of finches 150 years before scientists understood DNA. Technology and progressing science proved he was right, yet many struggle to understand how natural selection happens. Scholars use...
Howard Hughes Medical Institute
HIV Protease Inhibitors
How do doctors fight a virus that's constantly mutating? Show science scholars how we fight HIV using one of its own most fundamental processes through a thoughtful demonstration. The lesson focuses on how protease inhibitors prevent HIV...
Lincoln Public Schools
Cell Exploration Activities
Engage young biologists in exploring the mysteries of life with this collection of hands-on activities. Enlisting the help of numerous digital resources, students get an up-close look at the structure of plant and animal...
Serendip
The Molecular Biology of Mutations and Muscular Dystrophy
Different types of mutations cause unique types and degrees of muscular dystrophy. Scholars learn about the types of mutations and the impact on the body. They compare the location of the mutations and draw conclusions about how it is...
National Nanotechnology Infrastructure Network
Silver and Bandages: Assessment of Inhibition of Bacteria by Silver Colloid-Impregnated Bandages
Silver: more than jewelry, it's also a natural antimicrobial agent. An inquiry-based lesson asks collaborative groups to design and implement an experiment to test this property. Using samples of silver nanoparticles and a strain of...
Serendip
Where Does a Plant's Mass Come From?
Where does the mass for a growing tree come from? Scholars consider a few different hypotheses and guess which is correct. They then analyze data from different experiments to understand which concepts science supports.
Concord Consortium
Concord Consortium: Stem Resources: Dna to Protein
Investigate how the genetic code on a DNA strands controls what protein is produced with this collection of animations and 3D models. Explore an interactive 3D model of the double helix, watch an animation of transcription, and see the...
Other
National Center for Biotechnology Education: Dna50: Cut Out Model
Students construct DNA base pairs using a template. The base pairs can be used to assemble a large-scale DNA strand for the whole class.
BiologyWise
Biology Wise: How to Make a 3 D Dna Model Project
Describes the steps for how to make a model of DNA using colored polymer clay and wire. Students will gain a good understanding of the structure of DNA by doing this project.
Genome British Columbia
Genome British Columbia: Edible Dna [Pdf]
Students use food (licorice and marshmallows or fruit) to make models of DNA.
National Health Museum
Access Excellence: Genes, Dna, and Mutations
A good Access Excellence site with an introduction to the processes of transcription and translation, leading to a student modeling activity.
TeachEngineering
Teach Engineering: Dna Build
Students reinforce their knowledge that DNA is the genetic material for all living things by modeling it using toothpicks and gumdrops that represent the four biochemicals (adenine, thiamine, guanine, and cytosine) that pair with each...
National Health Museum
Access Excellence: Possible Models of Dna Replication
These images from Access Excellence are possible models for DNA replication. The illustrations clearly show the differences among the three ways DNA can replicate.
Concord Consortium
Concord Consortium: Molecular Workbench Showcase: Biotech
Simulations of common biotechnology techniques performed in a laboratory setting. Learn how to complete these techniques and what task they are used for in the lab.