Activity
Howard Hughes Medical Institute

Using DNA to Explore Lizard Phylogeny

For Teachers 6th - 12th
In a fun and interactive two-day lesson, learners sort anole lizard pictures by appearance. Next, they watch a video about the anoles and re-sort based on the information in the video. In addition to physical characteristics, budding...
Lesson Plan
LABScI

DNA Structure: Gumdrop Modeling

For Teachers 9th - 12th
DNA molecules hold the secrets that make us unique. The fourth of 12 lessons explores the structure of DNA by building candy models. After building the models, young scientists break their models to begin the process of DNA replication....
Activity
Howard Hughes Medical Institute

DNA Profiling Activity

For Teachers 9th - 12th
Everyone loves a good mystery ... can your class actually solve one? Partnered pupils take on the role of forensic investigators during a three-part activity focusing on DNA evidence processing. Learners discover the methods used to...
Activity
Howard Hughes Medical Institute

Viral DNA Integration

For Teachers 9th - Higher Ed
How do reverse transcriptase inhibitors work? Young virologists examine the function of azidothymidine, a drug doctors use to treat HIV patients, during a hands-on modeling activity. Groups create a strand of DNA from an HIV RNA strand...
Activity
Exploratorium

Secret Codon - Write a Message in DNA

For Teachers 6th - 12th
String up a message. Pupils string together colored beads to code a word or short phrase. Each color represents one of the four DNA bases. Using a combination of three bases, learners create an amino acid that stand for each letter of...
Lesson Plan
Serendip

UV, Mutations, and DNA Repair

For Teachers 9th - 12th
How effective are cells at repairing UV damage? An inquiry-based lesson has learners experiment with organism by exposing them to various levels of UV light and then examining their DNA after a period of time. Pupils test different...
Lesson Plan
National Association of Biology Teachers

Using the Discovery of the Structure of DNA to Illustrate Cultural Aspects of Science

For Teachers 9th - 12th
Times have changed—and so have science practices. An introductory lesson plan describing the components of DNA begins with a discussion of the discovery of DNA and its perception in different cultures and genders. Scholars then learn...
Unit Plan
Curated OER

Genome: The Secret of How Life Works

For Students 4th - 12th Standards
What do you have in common with a fruit fly? About 60 percent of your DNA. The resource, divided into two units, is intended for grades four to eight and another for high schoolers. Both units include eight lessons covering the...
Lesson Plan
Science 4 Inquiry

The Monster Mash

For Teachers 9th - 12th Standards
Young scientists create monsters by applying their knowledge of transcription and translation. They randomly find the DNA, assign it a codon, and build monsters piece by piece. 
Lesson Plan
Towson University

Case of the Crown Jewels

For Teachers 9th - 12th Standards
Can your biology class crack the Case of the Crown Jewels? Junior forensics experts try their hands at DNA restriction analysis in an exciting lab activity. The lesson introduces the concept of restriction analysis, teaches pipetting and...
Lesson Plan
Towson University

Chestnut Tree Lab

For Teachers 9th - 12th Standards
What will your class learn in a curious tale of a fungus, a virus, and a chestnut tree? Biology scholars discover the world of viral biocontrols through a DNA restriction lab. Groups research the decline of the American chestnut tree at...
Activity
Howard Hughes Medical Institute

Ebola: Disease Detectives

For Teachers 9th - Higher Ed
How did the Ebola virus first infect humans? Young virologists examine genetic sequences from the 2014 Sierra Leone outbreak to find similarities during a riveting activity. Following similar methods used by MIT and Harvard, partners...
Lesson Plan
Towson University

The Wildlife Forensics Lab

For Teachers 9th - 12th Standards
Can science put an end to the poaching of endangered species? Show your young forensic experts how biotechnology can help save wildlife through an exciting electrophoresis lab. Grouped pupils analyze shark DNA to determine if it came...
Lesson Plan
Curated OER

The Effect of Natural Selection on Genes, Traits and Individuals

For Teachers 9th - 12th Standards
Rotating through five stations, evolutionary biologists explore the question of how changes in DNA facilitate the changes in a population over time. High-quality, colorful cards of animals, skeletons, skulls, and DNA sequences can all be...
Activity
Exploratorium

Breakfast Proteins - Construct a Protein through Cereal Additions

For Teachers 6th - 12th
Match my cereal sequence. Pupils view a sequence made by colorful cereal rings and create copies of it. Learners must either remember or write down the sequence to transport the code to another location. Scholars replicate the cereal...
Activity
Howard Hughes Medical Institute

Biodiversity and Evolutionary Trees

For Teachers 9th - 12th
Compare what shells look like on the outside with what makes that happen on the inside. Scholars begin by sorting an various seashells by their physical characteristics into phylogenetic trees. They then conduct a DNA comparison of...
Unit Plan
Kenan Fellows

Unit 3: Genetic Variation

For Teachers 9th - 12th Standards
What happens when genes change? Junior genetic investigators examine the effects of mutation in the third unit of a four-part Biotechnology series. Individuals discover the types of mutations through a series of PowerPoints, then partner...
Lesson Plan
Beyond Benign

What is Biotechnology

For Teachers 6th - 8th
Examine the sequence of key events in the history of genetics. An engaging lesson asks scholars to sort events to create a timeline of biotechnology milestones. Arranging the events gives learners a perspective on the development of...
Lesson Plan
K20 LEARN

How EGG-ceptional Are We? (Biology)

For Teachers 9th - 12th Standards
Are women's eggs similar to chicken eggs? Scholars compare eggs from various species to better understand embryonic development. Connections to evolution through hands-on activities help to cement the new vocabulary introduced.
Lesson Plan
Oklahoma State University

Hairy Heredity

For Teachers 5th - 8th Standards
Young scholars learn that heredity comes down to the flip of a coin with this cross-curricular math and science lesson. Using smiley faces as a model, students toss coins to determine which dominant or recessive traits...
Lesson Plan
Virginia Department of Education

Adaptation and Evolution

For Teachers 9th - 12th Standards
Um may be the atomic symbol for confusion, but it won't be needed in this lesson. Scholars rotate through seven stations completing experiments, hands-on activities, writing exercises, and analysis. Stations include material on...
Lesson Plan
Field Museum

The Case of Darwin's Finches

For Teachers 7th - 12th Standards
One of the most striking pieces of evidence for Darwin's Evolution of Species was his observations of finches and how their beaks differed from island to island, depending on their primary food sources. So what would happen to the theory...
Activity
Howard Hughes Medical Institute

Understanding Variation

For Teachers 9th - Higher Ed Standards
Does where we live influence how our bodies express genetic traits? Explore variation in human skin color with an activity that incorporate video and hands-on learning. Individuals model the relationship between phenotypes and genotypes,...
Activity
Howard Hughes Medical Institute

Stalking the Genetic Basis of a Trait

For Teachers 9th - 12th Standards
Need an a-maize-ing lesson to show your class how regulatory genes work? If you use the well-written resource, they'll be all ears! Biology scholars discover the gene responsible for the evolution of the modern-day corn plant through a...