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Serendip
The Molecular Biology of Mutations and Muscular Dystrophy
Different types of mutations cause unique types and degrees of muscular dystrophy. Scholars learn about the types of mutations and the impact on the body. They compare the location of the mutations and draw conclusions about how it is...
Howard Hughes Medical Institute
Central Dogma and Genetic Medicine
Scientists work every day to find solutions to genetic diseases. Scholars learn about the process of gene sequencing, mutations, and the results. They explore genetic diseases and therapies to intervene and help and, through case...
Science 4 Inquiry
"Something Old, Something New..."
Young scientists learn about DNA replication through a video and model creation. They answer analysis questions before exploring the role of mutations and then complete a summative assessment.
Howard Hughes Medical Institute
Natural Selection and the Evolution of Darwin's Finches
Darwin explained the connection between species of finches 150 years before scientists understood DNA. Technology and progressing science proved he was right, yet many struggle to understand how natural selection happens. Scholars use...
Howard Hughes Medical Institute
The Making of the Fittest: Natural Selection and Adaptation
The pocket mouse can be light brown like the sands of the desert, or dark brown like the volcanic lava flows that are interspersed throughout New Mexico's Valley of Fire. It seems that predators have weeded out light colored mice in this...
Howard Hughes Medical Institute
Got Lactase? The Co-Evolution of Genes and Culture
Does the human body evolve as quickly as human culture? With a stellar 15-minute video, explore the trait of lactose intolerance. Only about 1/3 of human adults seem to still have the enzyme lactase and therefore, the ability to digest...
Howard Hughes Medical Institute
Ebola: Disease Detectives
How did the Ebola virus first infect humans? Young virologists examine genetic sequences from the 2014 Sierra Leone outbreak to find similarities during a riveting activity. Following similar methods used by MIT and Harvard, partners...
Howard Hughes Medical Institute
Icefish Adaptations
What adaptations exist in order for icefish to survive the subfreezing temperatures of the Antarctic Ocean? Middle and high schoolers can find out through watching a related 13-minute video and performing a simple investigation to...
Howard Hughes Medical Institute
Stalking the Genetic Basis of a Trait
Need an a-maize-ing lesson to show your class how regulatory genes work? If you use the well-written resource, they'll be all ears! Biology scholars discover the gene responsible for the evolution of the modern-day corn plant through a...
Howard Hughes Medical Institute
Lactase Persistence: Evidence for Selection
What's the link between lactase persistence and dairy farming? Biology scholars analyze data to find evidence of the connection, then relate this to human adaptation. Working individually and in small groups, learners view short video...
Virginia Department of Education
Viruses
Germs, parasites, and viruses, oh my! Facilitate a lesson on viruses as individuals explore functions of Archaea, Bacteria, and Eukarya. They learn how viruses compare with other organisms in nature and how they contribute to health...
Kenan Fellows
Unit 3: Genetic Variation
What happens when genes change? Junior genetic investigators examine the effects of mutation in the third unit of a four-part Biotechnology series. Individuals discover the types of mutations through a series of PowerPoints, then partner...
Serendip
Understanding the Biology of Cancer
After initial exposure to a carcinogen, a cancer diagnosis often takes more than a decade due to the slow buildup of mutated cells in the body. Scholars learn about the biology of cancer with a worksheet and discussion questions. They...
Curated OER
Cell Wall Recipe: A Lesson on Biofuels
Biotech engineers discover that changes in the DNA code for cell wall formation can help create crops better suited for biofuel production. They extract DNA from wheat germ. They decode paper strips with codes and relate the activity to...
Virginia Department of Education
Owl Family Natural Selection
How do genetic mutations within a population lead to future variations? Provide your class with the resources to answer this question and more upon completing an activity on natural selection. The entire class participates in a...
Children’s Hospital of Philadelphia
Case Study: The 1918 Influenza Pandemic – Factors Beyond the Biological that Influence the Spread of Disease
A very timely lesson looks at the social and political factors that affect the spread of disease. Using the 1918 Influenza Pandemic as a case study, pupils research factors that influenced the spread of the disease, including the role of...
Curated OER
Activity: Gummy Bear Genetics
Who's your Daddy ... and Mommy for that matter? Given a first-generation group of gummy bear offspring, young scientists must determine which bears are their parents. An activity worksheet covers the differences in genotypes and...
Virginia Department of Education
Evidence of Evolution
What an impression fossils make! In this activity, aspiring paleontologists view fossils and construct a timeline to further understand how the lack of natural adaptation caused historical organisms to become extinct. While they...
Howard Hughes Medical Institute
Biochemistry and Cell Signaling Pathway of the Mc1r Gene
How do mice have so much fur color variation over generations? Scholars illustrate protein structures based on amino acid sequences. Then, they analyze the signaling pathway in different-colored mice populations. This allows them to...
Howard Hughes Medical Institute
Developing an Explanation for Mouse Fur Color
Whether or not you think mice are nice, you'll love the colorful activity! Scholars examine evidence for evolution in the rock pocket mouse through video, discussion, and collaborative work. Learners watch a video regarding variation in...
University of California
Artificially Selecting Dogs
Selective breeding has resulted in some novel and beautiful or useful dogs over the years. Using the American Foxhound as an example, genetics learners find out how and why they came about. Then, in small groups, they select breeds to...
National Geographic
Genetic Markers: Connecting the Dots
Biology buffs simulate how genetic markers are passed among populations in order to understand how these markers can help anthropologists map human migration. A couple of volunteers leave the room while you walk the remaining learners...
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