Lesson Plan
Serendip

The Molecular Biology of Mutations and Muscular Dystrophy

For Teachers 9th - 12th
Different types of mutations cause unique types and degrees of muscular dystrophy. Scholars learn about the types of mutations and the impact on the body. They compare the location of the mutations and draw conclusions about how it is...
Interactive
Howard Hughes Medical Institute

Central Dogma and Genetic Medicine

For Students 9th - 12th Standards
Scientists work every day to find solutions to genetic diseases. Scholars learn about the process of gene sequencing, mutations, and the results. They explore genetic diseases and therapies to intervene and help and, through case...
Lesson Plan
Science 4 Inquiry

"Something Old, Something New..."

For Teachers 9th - 12th Standards
Young scientists learn about DNA replication through a video and model creation. They answer analysis questions before exploring the role of mutations and then complete a summative assessment.
Activity
Howard Hughes Medical Institute

Natural Selection and the Evolution of Darwin's Finches

For Teachers 6th - 12th Standards
Darwin explained the connection between species of finches 150 years before scientists understood DNA. Technology and progressing science proved he was right, yet many struggle to understand how natural selection happens. Scholars use...
Lesson Plan10:25
Howard Hughes Medical Institute

The Making of the Fittest: Natural Selection and Adaptation

For Students 8th - Higher Ed Standards
The pocket mouse can be light brown like the sands of the desert, or dark brown like the volcanic lava flows that are interspersed throughout New Mexico's Valley of Fire. It seems that predators have weeded out light colored mice in this...
Lesson Plan
1
1
Howard Hughes Medical Institute

Got Lactase? The Co-Evolution of Genes and Culture

For Teachers 8th - 12th Standards
Does the human body evolve as quickly as human culture? With a stellar 15-minute video, explore the trait of lactose intolerance. Only about 1/3 of human adults seem to still have the enzyme lactase and therefore, the ability to digest...
Activity
Howard Hughes Medical Institute

Ebola: Disease Detectives

For Teachers 9th - Higher Ed
How did the Ebola virus first infect humans? Young virologists examine genetic sequences from the 2014 Sierra Leone outbreak to find similarities during a riveting activity. Following similar methods used by MIT and Harvard, partners...
Lesson Plan
Howard Hughes Medical Institute

Icefish Adaptations

For Teachers 7th - 12th Standards
What adaptations exist in order for icefish to survive the subfreezing temperatures of the Antarctic Ocean? Middle and high schoolers can find out through watching a related 13-minute video and performing a simple investigation to...
Activity
Howard Hughes Medical Institute

Stalking the Genetic Basis of a Trait

For Teachers 9th - 12th Standards
Need an a-maize-ing lesson to show your class how regulatory genes work? If you use the well-written resource, they'll be all ears! Biology scholars discover the gene responsible for the evolution of the modern-day corn plant through a...
Activity
Howard Hughes Medical Institute

Lactase Persistence: Evidence for Selection

For Teachers 9th - 12th Standards
What's the link between lactase persistence and dairy farming? Biology scholars analyze data to find evidence of the connection, then relate this to human adaptation. Working individually and in small groups, learners view short video...
Lesson Plan
Virginia Department of Education

Viruses

For Teachers 9th - 12th
Germs, parasites, and viruses, oh my! Facilitate a lesson on viruses as individuals explore functions of Archaea, Bacteria, and Eukarya. They learn how viruses compare with other organisms in nature and how they contribute to health...
Unit Plan
Kenan Fellows

Unit 3: Genetic Variation

For Teachers 9th - 12th Standards
What happens when genes change? Junior genetic investigators examine the effects of mutation in the third unit of a four-part Biotechnology series. Individuals discover the types of mutations through a series of PowerPoints, then partner...
Lesson Plan
Serendip

Understanding the Biology of Cancer

For Teachers 9th - 12th Standards
After initial exposure to a carcinogen, a cancer diagnosis often takes more than a decade due to the slow buildup of mutated cells in the body. Scholars learn about the biology of cancer with a worksheet and discussion questions. They...
Lesson Plan
Curated OER

Cell Wall Recipe: A Lesson on Biofuels

For Teachers 5th - 8th
Biotech engineers discover that changes in the DNA code for cell wall formation can help create crops better suited for biofuel production. They extract DNA from wheat germ. They decode paper strips with codes and relate the activity to...
Lesson Plan
Virginia Department of Education

Owl Family Natural Selection

For Teachers 9th - 12th
How do genetic mutations within a population lead to future variations? Provide your class with the resources to answer this question and more upon completing an activity on natural selection. The entire class participates in a...
Lesson Plan
3
3
Children’s Hospital of Philadelphia

Case Study: The 1918 Influenza Pandemic – Factors Beyond the Biological that Influence the Spread of Disease

For Teachers 9th - 12th Standards
A very timely lesson looks at the social and political factors that affect the spread of disease. Using the 1918 Influenza Pandemic as a case study, pupils research factors that influenced the spread of the disease, including the role of...
Activity
Curated OER

Activity: Gummy Bear Genetics

For Students 9th - 12th Standards
Who's your Daddy ... and Mommy for that matter? Given a first-generation group of gummy bear offspring, young scientists must determine which bears are their parents. An activity worksheet covers the differences in genotypes and...
Lesson Plan
Virginia Department of Education

Evidence of Evolution

For Teachers 9th - 12th
What an impression fossils make! In this activity, aspiring paleontologists view fossils and construct a timeline to further understand how the lack of natural adaptation caused historical organisms to become extinct. While they...
Activity
Howard Hughes Medical Institute

Biochemistry and Cell Signaling Pathway of the Mc1r Gene

For Teachers 9th - 12th Standards
How do mice have so much fur color variation over generations? Scholars illustrate protein structures based on amino acid sequences. Then, they analyze the signaling pathway in different-colored mice populations. This allows them to...
Activity
Howard Hughes Medical Institute

Developing an Explanation for Mouse Fur Color

For Teachers 7th - 12th Standards
Whether or not you think mice are nice, you'll love the colorful activity! Scholars examine evidence for evolution in the rock pocket mouse through video, discussion, and collaborative work. Learners watch a video regarding variation in...
Lesson Plan
University of California

Artificially Selecting Dogs

For Teachers 6th - 12th
Selective breeding has resulted in some novel and beautiful or useful dogs over the years. Using the American Foxhound as an example, genetics learners find out how and why they came about. Then, in small groups, they select breeds to...
Lesson Plan
National Geographic

Genetic Markers: Connecting the Dots

For Teachers 8th - 12th
Biology buffs simulate how genetic markers are passed among populations in order to understand how these markers can help anthropologists map human migration. A couple of volunteers leave the room while you walk the remaining learners...

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