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Howard Hughes Medical Institute
Patterns in the Distribution of Lactase Persistence
We all drink milk as babies, so why can't we all drink it as adults? Examine the trend in lactase production on the world-wide scale as science scholars analyze and interpret data. Groups create pie charts from the data, place them on a...
Museum of Science
Elephant Toothpaste
Get a surprised reaction from trying out the chemical reaction. Scholars conduct a chemical experiment by adding yeast to hydrogen peroxide and dish soap in a plastic bottle. They learn that yeast contains a catalase enzyme that releases...
Howard Hughes Medical Institute
HIV Protease Inhibitors
How do doctors fight a virus that's constantly mutating? Show science scholars how we fight HIV using one of its own most fundamental processes through a thoughtful demonstration. The lesson focuses on how protease inhibitors prevent HIV...
Howard Hughes Medical Institute
Lactose Intolerance: Fact or Fiction
Around the world, about 2/3 of adult humans are lactose intolerant. Scholars work in small groups to discuss a few statements about lactose intolerance. Then, they watch a video on the topic and readdress each statement. Whole-class...
Nuffield Foundation
Digestion of Starch: Microbes
Sugar isn't good for you, but it's great for microbes. A simple experiment has pupils investigate the digestion of starch by microbes to produce sugars. They apply two bacterial cultures, an amylase solution, and distilled water on a...
Howard Hughes Medical Institute
Virus Hunters: Epidemiology of Nipah Virus
Who actually goes looking for a virus? Expose your class to the high-stakes life of an epidemiologist on the trail of the Nipah virus. Pupils engage in a short video, then examine how scientists predict, model, and find the source of...
Howard Hughes Medical Institute
Got Lactase? Blood Glucose Data Analysis
Many physicals include a blood glucose test, but what are doctors actually testing? Scholars graph and interpret blood glucose data, allowing them to observe the differences in lactase persistence and draw conclusions. They then connect...
Howard Hughes Medical Institute
Winogradsky Columns: Microbial Ecology in the Classroom
Substances that decompose with the help of living organisms do so at different rates. Scholars experiment with Winogradsky columns to determine the rate of decomposition, the oxygen and sulfide content changes, and bacteria levels. The...
Nuffield Foundation
Extracting DNA from Living Things
Help! Someone's trying to take my DNA! An interesting lab experiment has scholars use basic materials to extract DNA. By applying ethanol, cold water, and a protease enzyme, like pineapple juice, they pull strands of DNA from peas,...
Howard Hughes Medical Institute
The Making of the Fittest: Got Lactase? The Co-evolution of Genes and Culture
Got milk? Only two cultures have had it long enough to develop the tolerance of lactose as an adult. Learn how the responsible genes evolved along with the cultures that have been consuming milk. This rich film is supplied with a few...
Howard Hughes Medical Institute
Milk—How Sweet Is It?
Have you ever wondered why some people are lactose intolerant? Participants test simulated patients in a hands-on lab activity to find out! They learn about lactose intolerance by performing an experiment, analyzing data, and drawing...
Serendip
Using Molecular and Evolutionary Biology to Understand HIV/AIDS and Treatment
HIV mutates rapidly, making treatments challenging to find. Scholars learn about why it mutates so quickly and how scientists race to find treatments. The resource approaches the issue from both a molecular and evolutionary perspective...
Howard Hughes Medical Institute
Viral DNA Integration
How do reverse transcriptase inhibitors work? Young virologists examine the function of azidothymidine, a drug doctors use to treat HIV patients, during a hands-on modeling activity. Groups create a strand of DNA from an HIV RNA strand...
Serendip
Genetic Engineering Challenge – How Can Scientists Develop a Type of Rice That Could Prevent Vitamin A Deficiency?
Brown rice contains vitamins B and E, while white rice lasts longer in storage. The availability of rice around the world makes it a great candidate for genetic engineering. Scholars apply their knowledge of genetic engineering to solve...
Teach Engineering
Inside the DNA
Get your class to take a closer look at DNA. Pupils conduct research to determine the methods used by scientists to analyze the molecular structure of DNA. The class members investigate different types of molecular imaging along with gel...
Science Buddies
Science Buddies: Enzyme Catalyzed Reactions What Affects Their Rates?
Enzymes speed up chemical reactions by factors of at least a million. This project investigates some of the factors that affect how fast enzymatic reactions occur.
Science Buddies
Science Buddies: A Juicy Project: Extracting Apple Juice With Pectinase
This is a basic project on the effect of enzymes on apple slices. The goal of the project is to monitor enzyme activity by measuring the amount of apple juice released by pectinase.
Science Buddies
Science Buddies: Molecular Scissors
Ever used a pair of molecular scissors? Restriction enzymes are molecular scissors that cut DNA into pieces. Find out which enzymes will cut, and where by making a restriction map. Then you can figure out what will happen if you change...
Science Buddies
Science Buddies: Which Fruits Can Ruin Your Dessert?
Here is a basic project for investigating enzymes that prevent gelatin from solidifying. This way you can understand why it is some fruits are not recommended for inclusion when it comes to making gelatin.
K Science
K Science: Enzymes
Several animations illustrating how enzymes catalyze chemical reactions. Examine how temperature affects the enzymes and how toxins can alter the shape of the enzymes.
Science Buddies
Science Buddies: Liver Stinks!
Sometimes science can be really messy or use pretty disgusting ingredients. That is what it takes to understand how the world works, even if the experiment isn't pretty. If you like chemical reactions that stink and ooze foamy bubbles...
Science Buddies
Science Buddies: I Love Ice Cream, but It Doesn't Love Me: Lactose Intolerance
Pizza, milk shakes, and ice cream sundaes all contain dairy products, therefore they cannot be eaten by the majority of people around the world. Dairy products contain the sugar molecule lactose, and the majority of people on the planet...
Science Buddies
Science Buddies: Weeds Be Gone! Experiment That Affect Roundup Weed Killer
Experiment with factors that affect the activity of the weed killer Roundup. The Science Buddies project ideas are set up consistently beginning with an abstract, objective, and introduction, followed by a section on terms, concepts, and...
Science Buddies
Science Buddies: Explore Enzyme Activity With Toothpicks
In this activity, you will simulate an enzymatic reaction and explore what factors affect the activity of an enzyme.