Curated OER
The Watson-Crick Model of DNA Structure
Junior geneticists construct models of DNA to discover sequencing and pairing of nucleotides. They use the models to simulate protein synthesis and then translate the codes into physical traits. Finally, they use the traits to create a...
Concord Consortium
DNA: The Double Helix
Picture a double helix as a twisted ladder. Scholars see this image through a simulation that allows young scientists to observe a small fragment of DNA in many different formats. They compare the models, colors, bonds, and strands as...
Kenan Fellows
Unit 2: DNA Analysis
Ever wonder how they solve those mysterious murders in TV crime dramas? The second of four units in a Biotechnology series introduces scholars to the many methods of DNA analysis. Pupils create and run their own gel electrophoresis...
Curated OER
DNA Detectives
In order to understand DNA fingerprinting, advanced biology aces divise a crime scenario and analyze three different samples of lambda DNA. This creative lesson plan provides practice with micropipettes, electrophoresis boxes, and other...
Curated OER
Innocent or Guilty: A Lab on DNA Gel Electrophoresis
Learners use the prelab as an introduction to the importance of DNA fingerprinting- a form of identification that us being accepted by both scientific and leagl experts. They prepare a gel for electrophoresis. DNA fragments, which have...
Concord Consortium
DNA to Protein
Starting from a view of cells, a constructive simulation shows every step of building a new protein. It walks through transcription, translation, building amino acids, and folding the protein. Viewers control if it plays as a video or...
Teach Engineering
DNA Forensics and Color Pigments
Use food coloring in electrophoresis. The last segment in a four-part series mimics DNA fingerprinting by using chromatography. Teams conduct chromatography on food coloring to find colors that use similar pigmentation in their makeup.
Virginia Department of Education
Building a DNA Model
It has been decades since the discovery of DNA. Still, activities such building this DNA model allow blossoming scientists to better understand the components that form this overall structure. During this activity, they will also...
Virginia Department of Education
DNA Structure, Nucleic Acids, and Proteins
What is in that double helix? Explain intricate concepts with a variety of creative activities in a instructional activity that incorporates multiple steps to cover DNA structure, nucleic acids, and proteins. Pupils explore the history...
Gene Jury
DNA Detectives
Police find a man murdered in a local hotel, DNA everywhere, and now they need scholars' help. Budding detectives step into a crime scene playing the roles of victim, suspects, and investigators. They apply knowledge of criminology and...
Beyond Benign
Gelin’: Gel Electrophoresis Simulation
Take a look at a DNA fingerprint. Scholars run a gel electrophoresis simulation to examine the DNA of potential father cats in the eighth installment of an 18-part series. The lesson continues the series that explores DNA and its...
California Academy of Science
Color Vision Genetics Evolution Simulation
At one point, all mammals carried only two color receptors, but now most humans carry three. An informative presentation and hands-on activity demonstrate how this evolved through genetics. By participating in the activity, pupils...
Howard Hughes Medical Institute
Got Lactase? The Co-Evolution of Genes and Culture
Does the human body evolve as quickly as human culture? With a stellar 15-minute video, explore the trait of lactose intolerance. Only about 1/3 of human adults seem to still have the enzyme lactase and therefore, the ability to digest...
Curated OER
Forensic Files: A DNA Dilemma
Seventh-graders come in to science class to find a file on their desks detailing a crime to be solved! As a demonstration, you simulate the restriction of DNA samples and separate them by electrophoresis. From the gel, learners can...
Curated OER
DNA Replication
Students create a model of DNA and simulate replication with their models in an activity that uses licorice, colored marshmallows, and toothpicks. Students also label a diagram of replication and indicate major parts of the DNA molecule.
Chemistry Collective
Virtual Lab: DNA - Dye Binding: Equilibrium and Buffer Solutions
Your class is bound to be fascinated by this virtual lab! Young biochemists explore molecules that bind to specific sites on the DNA molecule through a skillful simulation. The lesson challenges learners to create a DNA-bound solution...
Curated OER
The Great Cafeteria Caper
Students extract DNA from their own hair roots. They run an electrophoresis gel to examine patterns of their DNA along with standard DNA. The experiment is based on a crime scene scenario.
Curated OER
DNA Sequencing Simulation
Students explore the Sanger sequencing method which produces a nested set of radioactive fragments from a template strand. They simulate the Sanger method of sequencing DNA, both visually and kinesthetically.
Curated OER
Constructing a Phylogenetic Tree Using DNA Sequence Data
Students analyze DNA sequence differences between organisms in order to establish a reasonable picture of the evolutionary relationships between them. They take the role of molecular biologists and make genetic changes and constructing...
Curated OER
DNA Fingerprinting
Students discuss DNA Fingerprinting and gel electrophoresis before participating in a crime solving activity. Students simulate their DNA using adding tape and complete the steps necessary to do a gel electrophoresis. They discuss the...
Curated OER
Sequencing the Cystic Fibrosis Gene: A Simulation
Ninth graders use this activity to simulate the sequencing of gene and to detect the presence of possible genetic defects. They use diagrams that represent bands of nucleotides in order to determine the sequence of a small piece of the...
Curated OER
The Coding of Protein Molecules by DNA
Students investigate the production of proteins by the DNA. In this protein synthesis lesson plan, students use paper models to explore transcription and translation to make proteins using DNA. Students answer 10 questions to demonstrate...
Curated OER
lambda DNA Fingerprinting Simulation
Students perform restriction digests on DNA samples from four individuals, and then search for similarities between the individuals by running the restriction fragments on an electrophoresis gel.
Curated OER
The Clark Family Story: Tracing the Cause of Hemophilia
Ms. Strohfeldt did not omit anything when she designed this comprehensive lesson plan on DNA mutation and sex-linked traits. Begin with a pretest as an anticipatory set. Read a case history of the Clark family and the occurrence of...