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Howard Hughes Medical Institute
The Making of the Fittest: The Birth and Death of Genes
Adaptations must be made as environments change. This fabulous presentation features Icelandic icefish, a transparent, scaleless specimen that even has colorless blood. Genetics and adaptations concepts are explored as scientists study...
Curated OER
Evolution
Explore the concept of evolution and cell biology; your class can work in groups to use the internet to view websites on evolution, take a quiz, and complete a lab activity.
Howard Hughes Medical Institute
Got Lactase? The Co-Evolution of Genes and Culture
Does the human body evolve as quickly as human culture? With a stellar 15-minute video, explore the trait of lactose intolerance. Only about 1/3 of human adults seem to still have the enzyme lactase and therefore, the ability to digest...
Curated OER
Variations in Living Things
Biology beginners observe traits in a collection of plant parts to realize the tremendous amount of genetic variation within a species. They consider rules of nature and discuss what would happen if they changed. They also examine data...
Curated OER
Building a DNA Molecule, Mitosis in Motion and Mutation Gossip
Students explore three lab experiments involving DNA, mitosis, and mutation. They complete activities and play games to review DNA, mitosis and mutation concepts. They build a DNA molecule and create flip cards representing mitosis in...
Curated OER
Genetic Variability
Using black and white construction paper, evolutionary biologists simulate the classic peppered moth study. They use beans in a frequency and natural selection exercise. Finally, they analyze germinated seeds for variations. All three...
Curated OER
Viruses/Infectious Diseases: What's Really Bugging You?
Middle school life science or health classes listen to an audio, visit websites, read different articles, and participate in a class-wide simulation about the spread of viruses. The lesson plan doesn't get into the mechanics of how...
Curated OER
Transcription and Translation Lab Activity
Students investigate DNA strands. They study the sequence to determine if it is DNA or RNA and write the mRNA nucleotide sequence. After stringing the beads together to create the mRNA sequence they translate it into an amino acid...
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Genes
Young scholars explore the history, inheritance and mutations of genetics. In this genetic lesson students complete experiments on DNA sequences.
Curated OER
Spork and Beans
Students examine natural selection, how it works and how it can cause microevolution. In this evolution lesson students complete a lab activity that shows the effects that natural selection has on organisms.
Curated OER
Constructing a Phylogenetic Tree Using DNA Sequence Data
Students analyze DNA sequence differences between organisms in order to establish a reasonable picture of the evolutionary relationships between them. They take the role of molecular biologists and make genetic changes and constructing...
Curated OER
Populations- The Survival of the Fittest
Students examine the ways that populations become diverse and how mutation changes the diversity of a population. In this exploratory instructional activity students study natural selection by completing a lab activity and...
Curated OER
Pharmaceutical Lesson Plan
Students are able to discuss and prepare a written summary of a scientific article about AIDS. They propose solutions to the opening activity of which drug is more effective in the fight against AIDS.
Curated OER
Using Yeast as an Ultraviolet Light Measurement Tool
High schoolers accurately measure the relationship between radiation dose and either survival or some genetic event such as mutation or recombination. They investigate the damage that was done to the DNA molecule as a result of exposure...
Howard Hughes Medical Institute
The Molecular Evolution of Gene Birth and Death
An upper-level biology activity, the comprehensive worksheet found here accompanies a PowerPoint and the video The Making of the Fittest: The Birth and Death of Genes, both of which are linked to through the website. Depending on the...
Curated OER
Constructing a Phylogenetic Tree
Young scholars are given the opportunity to analyze DNA sequence differences between organisms in order to establish a reasonable picture of the evolutionary relationships between them (Phylogenetic Tree). In the simulation form they...
Curated OER
Applied Evolution: How Will We Get There from Here?
High schoolers explore the basic process of natural selection and how people can manipulate that process today. The consequences of natural selection on daily life and the implications of evolutionary biology in basic and applied science...
Curated OER
Living in Water
Fourth graders perform a lab activity in which they examine the external structure of a preserved fish and find out why fish can survive and live in water. They perform a lab which is guided by a worksheet imbedded in this plan.
Curated OER
Creative Ways To Teach Evolutionary Concepts
Students explore evolutionary concepts in cartoons and lab activities. They describe and explain evolutionary concepts featured in a cartoon and participate in laboratory activities.
LABScI
Genetic Equilibrium: Human Diversity
Investigate the Hardy-Weinberg Principle to explain genetic equilibrium. The 10th lesson plan of a series of 12 is a laboratory exploration of genetic equilibrium. Your classes use a mixture of beans to model allele and genotype...
Curated OER
Scientist Simulation
High schoolers imagine themselves working as research scientists completing the end-steps of a molecular research project and interpreting the data. They compare the gene sequences of normal and abnormal mice and evaluate the protein...
Curated OER
Gene Regulation Mechanisms
Pupils explore genetics. They discuss how chromosomes and/or genes are regulated during the life of an organism. In a lab setting, students compare and contrast the genomic regulation of prokaryotic and eukaryotic cells using...
Curated OER
Scientist Simulation
Students envision the work of a research scientist, and the relationship between molecular biology and medicine. This activity allows students to imagine themselves working as research scientists by asking them to complete the end-steps...
Curated OER
Cracking the Code - Cloning Paper Plasmid
Students explore the "genetic code." They observe how genes may be manipulated for genetic research, gene cloning, and genetic engineering. In a lab setting, students examine the mechanics involved in cutting and ligating DNAs into a...