Curated OER
Innocent or Guilty: A Lab on DNA Gel Electrophoresis
Young scholars use the prelab as an introduction to the importance of DNA fingerprinting- a form of identification that us being accepted by both scientific and leagl experts. They prepare a gel for electrophoresis. DNA fragments, which...
Towson University
Mystery of the Crooked Cell
Can your class solve the Mystery of the Crooked Cell? Junior geneticists collaborate to learn about sickle cell anemia in a fascinating lesson plan. The included materials help them to examine the genetic factors behind the disease...
Curated OER
Gel Electrophoresis Simulation
Students identify the steps in a gel electrophoresis experiment and describe the role of enzymes. They examine the relationship between fragment size and migration rate in a gel. They view DNA fragments as well.
Curated OER
Rainbow Electrophoresis Lab
Students are introduced to the principles of gel electrophoresis. They practice loading gels and pipetting. In this laboratory activity, food color is separated into constituent pigments. The lab can be run with standard electrophoresis...
Curated OER
Fly Forensics
Freddy's Friendly Fruit Market is under attack by fruit flies, and it is up to your aspiring biologists to solve the crime! By reading and analyzing the phenotypes, detectives determine which fly is responsible. This memorable assignment...
Curated OER
The Electrophoresis of Human Hemoglobin
Learners are presented with a scenario that requires them to electrophoreses human hemoglobin samples in order to confirm a diagnosis of sickle cell anemia and/or to determine whether individuals in the scenario are carriers of the...
Curated OER
Gene Cloning Worksheet #1
In this gene cloning activity, students are given a gene sequence of DNA, plasmid DNA, 3 restriction enzymes, their cut patterns and a DNA ligase. They answer 6 questions about the results of using different restriction enzymes to cut...
Curated OER
Rainbow Electrophoresis
Students are introduced to the principles of gel electrophoresis and also provides an opportunity for students to practice loading gels and prpetting. In this laboratory activity, food color is used to separate into constituent pigments.
Curated OER
DNA Detectives
In order to understand DNA fingerprinting, advanced biology aces divise a crime scenario and analyze three different samples of lambda DNA. This creative lesson plan provides practice with micropipettes, electrophoresis boxes, and other...
Curated OER
Identification of Animals by Serum Electrophoresis
Students compare their unknown serum against a set of known serum standards and determine the animal source of their serum. They write a lab report to communicate their results.
Curated OER
The Electrophoresis of Human Hemoglobin
High schoolers analyze different types of hemoglobin. They use the technique of agarose gel electrophoresis to separate human hemoglobin molecules according to their electrical charge, size, and/or shape. Students relate the migration...
Curated OER
The Clark Family Story: Tracing the Cause of Hemophilia
Ms. Strohfeldt did not omit anything when she designed this comprehensive lesson plan on DNA mutation and sex-linked traits. Begin with a pretest as an anticipatory set. Read a case history of the Clark family and the occurrence of...
Curated OER
Protein Assays: Bio Rad and Page Gels
Students conduct the Biuret Test and the Bio Rad Protein Assay. They examine the spectrophotometer and graph molecular weights and the concentrations of the proteins investigated. They prepare solutions for the Bio-Rad test and use the...
Howard Hughes Medical Institute
DNA Profiling Activity
Everyone loves a good mystery ... can your class actually solve one? Partnered pupils take on the role of forensic investigators during a three-part activity focusing on DNA evidence processing. Learners discover the methods used to...
Curated OER
The Great Cafeteria Caper
Students extract DNA from their own hair roots. They run an electrophoresis gel to examine patterns of their DNA along with standard DNA. The experiment is based on a crime scene scenario.
Curated OER
Electrophoresis Analogy
Students participate in a simulation of electrophoresis separation of DNA fragments. They link arms to form DNA fragments with each student representing a nucleotide. As they move through an obstacle course they discover how fragments...
Curated OER
iDNAvestigation Exploration
Learners investigate DNA Fingerprinting techniques and applications. They participate in a scenario to analyze blood to discover who shattered a plexiglass backboards. In addition, they explain why the DNA fingerprint of blood from the...
Curated OER
DNA Fingerprinting through a Chemistry Lens
Young scholars explore DNA and restriction enzymes using fragments of DNA separated by electrophoresis on an agarose gel. They analyze the results to see "whodunit".
Curated OER
How is Foreign DNA Inserted into Organisms During the Genetic Engineering of Crops?
Students examine the positive benefits and negative consequences of genetically modified organisms following a lecture covering key biotech concepts and techniques. Students then conduct and experiment comparing the travel rate of...
Curated OER
DNA Race Track
Twelfth graders simulate a DNA fragment running through a gel electrophoresis in a class activity. Students work in teams as a DNA sample with each person on the team representing a fragment that moves through the gel at a specific speed.
Curated OER
Doggy DNA: The Power of PCR
Students listen as the teacher lectures about Polymerase Chain Reaction, and the technical information about its uses. They collect dog saliva and run/analyze a gel electrophoresis. Students use a computer to integrate information, and...
Curated OER
Comparison of Four-, Six-, And Eight-bp Cuts in Calf Thymus Dna
Students investigate the use of restriction enzymes to recognize a four-, six-, and eight-nucleotide sequence. They utilize restrictive endonucleases to cut Thymus DNA and compare results by viewing the DNA fragments on Agarose Gel...
Curated OER
"Who Done It?" Analysis of Molecular Fingerprints Left At the Scene of the Crime
Students examine different types of DNA fragments. They record and analyze their results. They determine who is the criminal in the story.
Curated OER
Kitchen Electrophoresis
Students investigate and explain the differences active transport versus passive transport. This lesson includes an individual and group activity. The basic steps of electrophores is the focus of inquiry. Identification of the pure...