Lesson Plan
Curated OER

cDNA Sequencing By Restriction Project

For Teachers 9th - 12th
Young scholars try to confirm the sequence of a given cDNA clone using the WWW tools and traditional restriction analysis. They grow the clone, prep the plasmid, cut the plasmid with restriction enzymes and compare their results to what...
Lesson Plan
Curated OER

The Cloning of Plasmid and Spinach DNA

For Teachers 10th - 12th
Students will first extract genomic DNA from spinach and perform a restriction enzyme digestion on both the spinach DNA and the plasmid using the same restriction enzyme. They then ligate the cut plasmid DNA with the cut spinach DNA in...
Lesson Plan
Curated OER

DNA Fingerprinting

For Teachers 9th
Ninth graders investigate what restriction enzymes do, and explain how a DNA sample can link a suspect to a crime.
Lesson Plan
Curated OER

Selecting Soil Organisms in Compost

For Teachers 12th - Higher Ed
Students conduct an experiment to demonstrate that many of the enzyme systems needed to break down society's wastes exist in nature among the decomposers in a compost pile. They culture compost bacteria on starch agar to examine the...
Lesson Plan
Curated OER

Selecting Soil Organisms in Compost

For Teachers 12th - Higher Ed
Students demonstrate that many of the enzyme systems needed to break down--and therefore clean up-society's wastes already exist in nature among the decomposers. They select the best starch-munching organisms by altering the environment...
Lesson Plan
Curated OER

Cloning of Plasmid and Spinach DNA

For Teachers 12th - Higher Ed
Students ligate fragments of genomic DNA from spinach into a vector plasmid. They perform a restriction enzyme digestion. Student use a ligated DNA molecule to transform E. coli cells. Students analyze their procedures and outcome of...
Lesson Plan
Curated OER

Genetics and Molecular Biology

For Teachers 9th - 10th
Young scholars create DNA models using colored construction papers. In this biology lesson, students identify enzyme restriction sites. They model how DNA plasmids replicate when taken up by a bacterial cell.
Lesson Plan
Nuffield Foundation

Investigating the Effect of Temperature on the Activity of Lipase

For Teachers 9th - 12th
How does temperature affect lipase activity? Young scholars conduct an experiment to collect data on the interaction of lipase at different temperatures. They add lipase to a solution of milk, sodium carbonate, and phenolphthalein and...
Lesson Plan
Curated OER

The Great Cafeteria Caper

For Teachers 11th - Higher Ed
Students extract DNA from their own hair roots. They run an electrophoresis gel to examine patterns of their DNA along with standard DNA. The experiment is based on a crime scene scenario.
Lesson Plan
Curated OER

Producing a Strain of E. coli that Glows in the Dark

For Teachers 8th - 12th
Students observe the experimental process called bacterial transformation and demonstrate phenotype changes in bacteria that have been transformed with an antibiotic-resistance gene and a metabolic marker. They create a luminescent...
Lesson Plan14:52
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Howard Hughes Medical Institute

The Making of the Fittest: Got Lactase? The Co-evolution of Genes and Culture

For Teachers 8th - Higher Ed Standards
Got milk? Only two cultures have had it long enough to develop the tolerance of lactose as an adult. Learn how the responsible genes evolved along with the cultures that have been consuming milk. This rich film is supplied with a few...
Lesson Plan
Curated OER

Characterization of the Bioluminescence (Lux+) Gene E. coli

For Teachers Higher Ed
Students grow E. coli strain HB101, which contains the plasmid pUCD607 with the bioluminescence (Lux+) gene. The plasmid containing the Lux+ gene is isolated from the E. coli, then characterized by restriction analysis.
Lesson Plan
Curated OER

The Four Groups of Biologically Important Compounds

For Teachers 7th - 12th
This is not they typical set of teacher instructions. It is an organized chart of the important organic compounds. For each, the involved elements, the name of the building block monomers, the names of polymers, extra information, and a...
Lesson Plan
Curated OER

Living Environment 2004

For Teachers 9th - 12th
In this living environment worksheet, learners answer 30 multiple choice questions and 42 short answer questions in preparation for the Regents exam.
Lesson Plan
Virginia Department of Education

Physical and Chemical Properties of Water

For Teachers 9th - 12th
How can you effectively provide detailed concepts of water properties to your high school class in a way they find exciting and challenging at the same time? By letting them play, of course! Through a variety of...
Lesson Plan
Curated OER

Jeopardy

For Teachers 9th - 12th
High schoolers played a game of Jeopardy where there was five categories with five questions each in order to assess the retention of concepts taught over the semester. The categories included: Graphing/Summarizing/ Scientific Method,...
Lesson Plan
Curated OER

Identification of Gram Negative Bacilli

For Teachers 9th - Higher Ed
In this biology worksheet, students review the procedures used to complete the lab activity and then examine the purpose and add the information while answering the questions.
Lesson Plan
Curated OER

From Gene to Protein Study Guide

For Teachers 12th - Higher Ed
In this biology worksheet, students review and answer different questions based upon the molecules of DNA and RNA. They look at the specific protein order of the DNA strand and its synthesis.
Lesson Plan
Curated OER

Biological Molecules

For Teachers 9th
Ninth graders examine the structure and function of biomolecules. In this food molecule instructional activity, 9th graders will examine various  types of biomolecules such as  carbohydrates, lipids, proteins, and nucleic...
Lesson Plan
LABScI

The Digestive System: Where Does Food Go?

For Teachers 9th - 12th
Would you believe that your digestive system stretches to five times your height?! Help your pupils to understand this relationship as they work through the laboratory exercise. The first instructional activity of a 12-part series is a...
Lesson Plan
Curated OER

Energy, Matter, and Organization

For Teachers 10th
Tenth graders review the Energy, Matter, and Organization unit. They have one week to complete an essay. Students must submit a concept map or drawing. The activity is introduces by reading a short story line which presents a simple...
Lesson Plan
Towson University

Case of the Crown Jewels

For Teachers 9th - 12th Standards
Can your biology class crack the Case of the Crown Jewels? Junior forensics experts try their hands at DNA restriction analysis in an exciting lab activity. The lesson introduces the concept of restriction analysis, teaches pipetting and...
Lesson Plan
Serendip

Using Molecular and Evolutionary Biology to Understand HIV/AIDS and Treatment

For Teachers 9th - 12th Standards
HIV mutates rapidly, making treatments challenging to find. Scholars learn about why it mutates so quickly and how scientists race to find treatments. The resource approaches the issue from both a molecular and evolutionary perspective...
Lesson Plan
Curated OER

DNA on Stick

For Teachers 10th - 12th
Students experience a "hands-on" activity to get visual evidence of the physical nature of DNA and the process of DNA purification. They explore one method of chromosomal DNA isolation and DNA extraction.

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