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Curated OER
Creating an Enzyme-Substrate Model
High schoolers explore the reaction rates of an enzyme-mediated reaction through experimentation. In small groups, they use everyday objects to demonstrate the effects of environmental variables on enzyme function.
Students graph and...
Cornell University
Discovering Enzymes
Explore the function of enzymes through a series of lab investigations. Learners use household enzymes such as hydrogen peroxide to model the role of enzymes. The enzymes break down proteins with and without a catalyst.
Curated OER
An Enzyme- Substrate Model
Learners explore reaction rates of an enzyme-mediated reaction. They examine the effects of environmental variables on enzyme function. Students collect, graph, and analyze data relating to the reaction.
Curated OER
Enzyme Reaction Rates Using Toothpicks
Students pretend to be enzyme that breaks toothpicks in timed intervals. They complete calculations to determine how many toothpicks are broken per second to determine the rate of reaction of the enzyme.
Curated OER
The Role of Enzymes
Students explore the role of enzymes in chemical reactions. In this enzymes lesson plan, students use hydrogen peroxide and manganese dioxide to observe a chemical reaction. Students observe the rates of reactions of chalk, hamburger,...
Curated OER
Are Enzymes Specific for Their Substrates?
Students discover enzyme to substrate specificity. The experiment uses samples of glucose and lactose in combination with the enzyme lactase. Students observe the reaction between the lactose and the lactase; the lack of a reaction...
Curated OER
Investigating Factors That Affect Rate of Enzyme Action
Students explore the properties of enzymes. In this chemical reaction lesson, students explore enzymes through a Web-quest and investigative study. Students will collect and summarize data and create a class presentation. This lesson is...
Curated OER
Enzyme Action
Students work with models of substrates and of enzymes and test the digestion of lactose with lactase. They determine if digestion of lactose has or has not occurred.
Curated OER
Cut-off Genes
Investigate the relationships between different deep-sea organisms by DNA sequencing. A worksheet provides instructions for DNA sequencing and space to work. They simulate gel electrophoresis by cutting out paper "DNA strands."...
Curated OER
Science Lesson: Chocolate Flavored Cherries
Students are able to identify start and stop sequences in DNA. They are able to model using restriction enzyme and ligase to remove sections of DNA and reattach them. Students are introduced to the process of recombinat DNA through the...
Curated OER
A Model of a Bacterial Plasmid
Students construct a plsmid model with the materials provided and be able to use it to define certain terms and explain other practical applications of genetic engineering. This simulation allows the students to work through the diagram...
Curated OER
Water-holding Capacity of Earth Materials
Young scholars design and conduct an experiment to test their ideas about how to speed up or slow down the rate of an enzyme-catalyzed reaction. They have access to an array of physical and chemical factors that might influence enzyme...
Cornell University
Who’s Got The Flu?
Become an immunologist for the day. Scholars elicit the use of the enzyme-linked immunoabsorbent assay (ELISA) to diagnose an infectious disease. Through the process, they learn about the immune system response to infectious diseases.
Cornell University
Extracting DNA
Uncover the basics of DNA structure through exploration activities. Collaborative groups build DNA models and recreate the process of replication. Then, using plant cells such as peas or strawberries, they extract a DNA sample.
Curated OER
DNA Replication
Learners create a model of DNA and simulate replication with their models in an activity that uses licorice, colored marshmallows, and toothpicks. Students also label a diagram of replication and indicate major parts of the DNA molecule.
Kenan Fellows
Absorbance Curves: Using Spectrophotometers to Quantize the Effects of a Strong Acid on a Buffer
The Henderson-Hasselbalch equation combined logarithmic terms with the application of carbonic acid as a buffer solution. Scholars learn investigate equation and its applications through hands-on experiments. They collect data and...
Curated OER
Inquiry into Consumer Products
Students recognize different consumer products, found in and around the home, that have reactive or denaturing properties when used together. They explore chemical and physical properties of each product by identifying chemical formulas...
LABScI
The Digestive System: Where Does Food Go?
Would you believe that your digestive system stretches to five times your height?! Help your pupils to understand this relationship as they work through the laboratory exercise. The first instructional activity of a 12-part series is a...
Curated OER
Dinosaur and DNA Days
Biology stars extract DNA samples from beef thymus and then examine its properties. They use enzymes to digest the DNA samples, and then use electrophoresis to separate fragments. Finally, they discuss methods and principles of...
Curated OER
Toothpick Breakdown
Fourth graders model the activity of an enzyme acting on a substrate and observe relationships. Have students place toothpicks in a pile. One member of the team should break as many toothpicks as possible, in 10 seconds.
Curated OER
Enzymatic Reaction
Students explore the effect enzymes have on reactions. They demonstrate the process of enzymatic reaction by making cheese. after experimentation, they answer a series of questions.
Curated OER
Transcription, Translation, and the Genetics of Microbes
Students construct various virus models using Fruit loops and Alphabits to represent nucleotides and molecules. They constructs capsomeres using shoes as the capsomeres and discuss various viruses.
Curated OER
Applied Evolution: How Will We Get There from Here?
Students explore the basic process of natural selection and how people can manipulate that process today. The consequences of natural selection on daily life and the implications of evolutionary biology in basic and applied science is...
Curated OER
DNA Recombination II
Learners model recombination in DNA. They color the DNA sample and cut it out. Students use their "restriction enzymes" to cut the DNA into specific fragments. They separate the fragments using the "gel electrotrophoresis." Learners...