Civil rights meets biotechnology in a instructional activity that scrutinizes the collection of DNA of citizens who have been arrested, but not yet convicted of a crime. Real-life cases are examined in which the DNA of a relative was used to identify a criminal, a law enforcement search went on unnecessarily due to a contaminated DNA sample, and a man wrongfully imprisoned for 19 years was exonerated via DNA analysis. Use this instructional activity to spur a passionate bioethics debate.