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Interactive
Cold Spring Harbor Laboratory

A Half DNA Ladder Is a Template for Copying the Whole

For Students 9th - 12th Standards
The experiment known as one of the most beautiful experiments in biology changed the way we think about DNA. Learn about the experiment and the scientists who designed it—as well as the scientists who built on the results—with an online...
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Worksheet
Curated OER

Mutations and Gene Regulation

For Students 9th - 12th
Teenaged scientists can use this quiz or study guide to show off their understanding of genetic mutations and their causes; includes short answer, multiple choice, matching, and more.
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Lesson Plan
Curated OER

Using Amino Acid Sequences to Show Evolutionary Relationships

For Teachers 9th - 12th
Compare protein fragments, count amino acids, and use the information to explore common ancestry. The resource mentions a student worksheet, however, a separate printable worksheet is not provided. The exercises are written into the...
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Lesson Plan
Curated OER

How Mutations Lead to Changes in Cell Structure and Function

For Teachers 9th - 12th
Pupils investigate how mutations lead to changes in cell structure and function. They construct an oligonucleotide, identify a protein sequence, design a step-by-step mechanism of how they think cells repair damaged DNA, and prepare and...
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Lesson Plan
Curated OER

Using Amino Acid Sequences to Show Evolutionary Relationships

For Teachers 10th - 12th
Junior biologists compare the amino acid sequences from fragments of five different globin molecules. They count the letter differences between each species pair. They construct a graphic representation of the evolutionary relationships...
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Lesson Plan
Curated OER

Evolutionary Relationships Based Upon Comparative Genetics

For Teachers 9th - 12th
High schoolers investigate the protein cytochrome c in an attempt to use its genetic chemistry to study possible evolutionary relationships between organisms. The lesson integrates technology with the use computers to perform DNA analysis.
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Lesson Plan
Curated OER

DNA: The Human Body Recipe

For Teachers 4th - 7th
Students describe DNA and the roles in which engineers are involved with the human body.  In this DNA lesson students participate in a class demonstration. 
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PPT
Curated OER

DNA

For Teachers 10th - 12th
The question of the structure and function of DNA being the same in almost all organisms is raised here. You will find this PowerPoint a great summary of the building blocks and replication of DNA. The differences between prokaryotes and...
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PPT
Curated OER

More Basic Biotechnology Tools

For Teachers 7th - 12th
You can use these slides to explain the many complicated steps of the Polymerase Chain Reaction. The diagnostic and forensic uses of gel electrophoresis are detailed. This PowerPoint could be used to communicate facts, or to prompt...
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PPT
Curated OER

Genetics and Genetic Engineering

For Teachers 9th - 12th
Pretty purple slides present a plethora of jargon related to genetic engineering. Most of them have one term across the top and a brief explanation of that term below. They are arranged in alphabetical order, which may not be the most...
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Worksheet
Curated OER

DNA. RNA, and Proteins

For Students 9th - 12th
A comprehensive five-page quiz or study guide covering DNA and its related processes. Young geneticists will need a strong understanding in order to complete this handout, which includes multiple choice, matching, compare/contrast, and...
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Lesson Plan
Curated OER

Identifying Disease Genes using BLAST

For Teachers 9th - 12th
Students navigate the National Center for Biological Information (NCBI) website and BLAST program to conduct a variety of biological assignments.
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Worksheet
Curated OER

RNA and Gene Expression

For Students 10th - Higher Ed
In this RNA worksheet, students compare and contrast RNA from DNA. Students complete 1 multiple choice and 8 true or false questions.
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Lesson Plan
Curated OER

Learning the Structure and Function of DNA

For Teachers 9th - 10th
Young scholars read about Humane Genome Project, examine structure and function of DNA, and participate in gel-electrophoresis lab. They complete Internet activity to test their knowledge of DNA.
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Lesson Plan
Curated OER

Games and Activities to Teach Molecular Genetics

For Teachers 9th - 12th
Students demonstrate a working knowledge of cell interactions such as DNA replication, protein synthesis (transcription and translation), through active participation in a cooperative group.
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Lesson Plan
Curated OER

DNA Sequencing Simulation

For Teachers 9th - 11th
Students explore the Sanger sequencing method which produces a nested set of radioactive fragments from a template strand. They simulate the Sanger method of sequencing DNA, both visually and kinesthetically.
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Worksheet
Curated OER

Mutations and Genetic Change

For Students 10th - Higher Ed
In this genetic mutations worksheet, students compare and contrast different types of mutations including point mutations, silent mutations, and frameshift mutations. This worksheet has 5 matching, 4 fill in the blank, and 3 short answer...
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Lesson Plan
Curated OER

The Cytochrome-C Lab

For Teachers 6th - 12th
Young scholars examine a method biologists use to try to determine relationships. They examine how amino acid sequences have been determined for a number of proteins, and how scientists can make inferences about DNA based on the amino...
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Worksheet
Curated OER

Replication of DNA

For Students 10th - Higher Ed
In this DNA worksheet, students read about the DNA replication process, step by step. Then students complete 1 multiple choice and 4 short answer questions.
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Lesson Plan
Curated OER

DNA Code

For Teachers 5th - 6th
Students synthesize information gathered from the web on reading the DNA code. In this upper-level biology activity, students use an online resource to gain information about DNA codes and then create posters on what they have learned....
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Lesson Plan
Curated OER

Groovy DNA Beads

For Teachers 7th - 10th
Learners create models of DNA and RNA using string and beads. They use beads representing the four nitrogenous bases of DNA to create a portion of a strand of DNA, and it's corresponding RNA. Then, students examine how many of their...
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Lesson Plan
Curated OER

DNA Blueprint for Life

For Teachers 6th - 8th Standards
Did you know that meat tenderizers contain DNA cutting enzimes? Did you know that you can isolate your own DNA? Or the DNA of fruit? Explore with your learners the DNA world with a series of experiments using readily available materials...
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Lesson Plan
Curated OER

Genetic Research: Decisions to be Made

For Teachers 9th - 12th
Learners examine the genetics involved in the human genome. They brainstorm the advantages and disadvantages to this discovery. They research different experts opinion and write a case study which addresses an ethical dilemma.
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Lesson Plan
Curated OER

Enhancing Students' Problem-Solving Abilities

For Teachers 9th - 12th
Students analyze the results of a hypothetical cloning experiment using a restriction endonuclease map obtained from an on-line data source. They answer the question, "How can I tell if the DNA I have obtained from this hypothetical...

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