Cold Spring Harbor Laboratory
A Gene Is a Discrete Sequence of DNA Nucleotides
Frederick Sanger won two Nobel prizes for protein sequencing and DNA sequencing. Young scientists learn about Dr. Sanger's research and amazing discoveries. They read an article and a biography, view videos and animations, and apply...
Curated OER
AP: Chapter 20: DNA Technology
This nine-page biotechnology resource contains six pages of questions regarding DNA technology. Questions cover cloning, restriction enzymes, the polymerase chain reaction, different techniques, the human genome project, and more. The...
Cold Spring Harbor Laboratory
A Genome Is an Entire Set of Genes
Today researchers identify a gene suspected of causing a genetic disease in a matter of days rather than years, thanks to the Human Genome Project. Young scientists learn about the Human Genome Project and the scientists who designed the...
Curated OER
The Watson-Crick Model of DNA Structure
Junior geneticists construct models of DNA to discover sequencing and pairing of nucleotides. They use the models to simulate protein synthesis and then translate the codes into physical traits. Finally, they use the traits to create a...
Curated OER
Learning the Structure and Function of DNA
Young scholars read about Humane Genome Project, examine structure and function of DNA, and participate in gel-electrophoresis lab. They complete Internet activity to test their knowledge of DNA.
Howard Hughes Medical Institute
Understanding Variation
Does where we live influence how our bodies express genetic traits? Explore variation in human skin color with an activity that incorporate video and hands-on learning. Individuals model the relationship between phenotypes and genotypes,...
Curated OER
Scientist Simulation
Students envision the work of a research scientist, and the relationship between molecular biology and medicine. This activity allows students to imagine themselves working as research scientists by asking them to complete the end-steps...
Curated OER
Electrophoresis Analogy
Students participate in a simulation of electrophoresis separation of DNA fragments. They link arms to form DNA fragments with each student representing a nucleotide. As they move through an obstacle course they discover how fragments...
Curated OER
Scientist Simulation
Students imagine themselves working as research scientists completing the end-steps of a molecular research project and interpreting the data. They compare the gene sequences of normal and abnormal mice and evaluate the protein product...
Curated OER
Identifying Disease Genes using BLAST
Students navigate the National Center for Biological Information (NCBI) website and BLAST program to conduct a variety of biological assignments.
Curated OER
Polymerase Chain Reaction (PCR)
Students explore how PCR works through various activities. In this biology lesson, students explain how PCR generate copies of DNA. They simulate the process using an online interactive website.
Curated OER
Sequence Alignment
High schoolers explore the uses of sequence alignment. In this DNA lesson students complete several experiments on sequencing and algorithms.
Curated OER
DNA
Students explore the basics of DNA and its history. In this DNA lesson students extract DNA from fruits and understand how it is used in forensics.
Curated OER
Who Owns Rights to Pharmacogenetic Information?
Students develop an understanding of the rationale of ownership over scientific information. They research commercial applications of DNA sequences. They analyze how to evaluate medical ethics issues.
Curated OER
BLAST Algorithm
Students explore a series of activities on using BLAST. In this biology lesson, students explain the significance of BLAST in DNA query. They give real world applications of BLAST.
Curated OER
DNA and RNA
Tenth graders research the history and discovery of DNA. Using their text, they label a basic DNA structure and the composition of genes. They explain how RNA and DNA differ from one other and discuss the processes of transcription and...
Curated OER
Whose DNA Is That?
Students investigate the use of technology in order to identify different sequences of amino acids by using online web tools. They enhance problem solving skills with amino acid identification skills and strengthening comfort with using...