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Lesson Plan
Curated OER

Cut-Off Genes

For Teachers 9th - 12th
Students explain the concept of gene sequence analysis. In this gene lesson, students draw inferences about phylogenetic similarities of different organisms.
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Lesson Plan
Curated OER

Osmosis and the Cell Membrane-part 2

For Teachers 7th - 9th
Students participate in a review of diffusion and the basic properties of the cell membrane before exploring the process of osmosis in a lab activity. Using shell-less eggs that have soaked in various solutions, students make...
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Lesson Plan
Curated OER

Using VNTR Analysis to Identify Guilt at a Crime Scene

For Teachers 9th - 12th
Students collect DNA from cheek cells. They compare and contrast the processes of DNA replication and PCR. They discuss how this information can be used to determine guilt at crime scenes.
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Worksheet
Curated OER

Biotechnology

For Students 6th - 12th
In this biology worksheet, students complete a crossword puzzle with 23 questions on biotechnology. They identify the benefits and ethical issues about biotechnology.
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Lesson Plan
Curated OER

DNA Fingerprinting: You Be the Judge!

For Teachers 9th - 12th
Students use their knowledge of DNA fingerprinting to evaluate the use fingerprints in courts, and will address the ethics of establishing a national database of fingerprints.
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Lesson Plan
Curated OER

"Who Done It?" Analysis of Molecular Fingerprints Left At the Scene of the Crime

For Teachers 9th - 12th
Students examine different types of DNA fragments. They record and analyze their results. They determine who is the criminal in the story.
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Lesson Plan
Curated OER

DNA Fingerprinting: You Be the Judge!

For Teachers 9th - 12th
High schoolers explore DNA fingerprinting. Students discover how DNA fingerprinting is done and judge the validity. They evaluate the use of certain prints in courts and address the ethics of establishing a national database of...
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Lesson Plan
Curated OER

Sequencing the Cystic Fibrosis Gene: A Simulation

For Teachers 9th
Ninth graders determine nucleotide sequences. They identify those base sequences that are normal, those that are normal variants and those that cause cystic fibrosis. Students use DNA nucleotide sequences to determine amino acid...
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Lesson Plan
Curated OER

Who Done It?

For Teachers 6th - 12th
Students work in groups to solve various murder mysteries using DNA evidence to implicate suspects. Teams compete to solve the crimes the fastest, while using various scientific methods to accomplish their task.
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Lesson Plan
Curated OER

Molecular Evolution in Plants

For Teachers 9th - 12th
Learners examine chlorophylls. They explore the absorbing pigments in a variety of plants. Through activities, students determine spectrophotometrically. They compare plant proteins from the family Brassicace to assess the level of...
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Lesson Plan
Curated OER

RFLP Paternity Testing: A Simulation

For Teachers 9th - 12th
Students use simulated autorads to discover the principle utilized to determine paternity.
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Lesson Plan
Curated OER

Shellfish Shenanigans

For Teachers 12th
Twelfth graders create simulations of a reality-based TV show that investigates the near death of a contestant from a seafood meal. They examine the physical symptoms of anaphylactic shock, and create protein fingerprints.
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Lesson Plan
Curated OER

DNA Fingerprinting with Restriction Enzymes

For Teachers 6th - 12th
Young scholars will illustrate how restriction enzymes work by piecing together parts of a puzzle. Then they apply this knowledge to help them analyze genetic evidence from the scene of a crime as well as to help them comprehend how a...
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Lesson Plan
Curated OER

Molecular Approaches to Evolution

For Teachers 9th - 12th
Students are introduced to working with molecular data. The first activity does both simulated and original data are used to compare amino acid, protein or DNA differences to construct phylogenetic trees or cladograms. These activities...
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Lesson Plan
Curated OER

The Electric Sieve

For Teachers 9th - 12th
Students examine different mixtures and how they can be separated.  For this electric sieve lesson students complete an activity that allows them to separate mixtures.
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Lesson Plan
Curated OER

Determination of Phylogenetic Relationships Using Restriction Analysis

For Teachers 9th - 10th
Students applied various mathematical analyses to interpret their data. By using the resulting DNA fragment patterns from several enzymes students established a possible evolutionary relationship among the mice.
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Lesson Plan
Curated OER

Restriction Enzymes

For Teachers 10th - 12th
Students explore enzymes and enzyme combinations. They examine and cut up and practice matching DNA sequences.
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Lesson Plan
Curated OER

What Repair Proteins are Expressed in C-Ferns After Exposure to Varying Amounts of UV Radiation?

For Teachers 9th - 12th
Students examine the life cycle of c-ferns. They complete experiments on the organisms exposing them to differnet amount of UV radiation. They collect data and analyze their results.
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Lesson Plan
Curated OER

Operating the spectrophotometer

For Teachers 10th - 12th
Working in small groups, young scholars explore the operation of spectrophotometer. Using the spectrophotometer, they investigate Beer's Law with everyday items.
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Lesson Plan
Curated OER

Biotechnology

For Teachers 9th - 12th
Students are introduced to the topic of biotechnology. Using the internet, they research issues that have been improved or brought about because of biotechnology advancements. In groups, they participate in activities in which they...
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Lesson Plan
Curated OER

DNA Sequencing Model Lab

For Teachers 10th - 12th
Students pretend they are each genetic engineers with a test tube of unknown DNA (PCR'd) possibly taken from blood cells of someone with a genetic condition.
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Lesson Plan
Curated OER

DNA Fingerprinting

For Teachers 9th
Ninth graders investigate what restriction enzymes do, and explain how a DNA sample can link a suspect to a crime.
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Lesson Plan
Curated OER

Cloning of Plasmid and Spinach DNA

For Teachers 12th - Higher Ed
Young scholars ligate fragments of genomic DNA from spinach into a vector plasmid. They perform a restriction enzyme digestion. Student use a ligated DNA molecule to transform E. coli cells. Students analyze their procedures and...
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Lesson Plan
Curated OER

The Cloning of Plasmid and Spinach DNA

For Teachers 10th - 12th
Young scholars will first extract genomic DNA from spinach and perform a restriction enzyme digestion on both the spinach DNA and the plasmid using the same restriction enzyme. They then ligate the cut plasmid DNA with the cut spinach...

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