Lesson Plan
Curated OER

cDNA Sequencing By Restriction Project

For Teachers 9th - 12th
Young scholars try to confirm the sequence of a given cDNA clone using the WWW tools and traditional restriction analysis. They grow the clone, prep the plasmid, cut the plasmid with restriction enzymes and compare their results to what...
Lesson Plan
Curated OER

The Cloning of Plasmid and Spinach DNA

For Teachers 10th - 12th
Students will first extract genomic DNA from spinach and perform a restriction enzyme digestion on both the spinach DNA and the plasmid using the same restriction enzyme. They then ligate the cut plasmid DNA with the cut spinach DNA in...
Lesson Plan
Curated OER

Selecting Soil Organisms in Compost

For Teachers 12th - Higher Ed
Students conduct an experiment to demonstrate that many of the enzyme systems needed to break down society's wastes exist in nature among the decomposers in a compost pile. They culture compost bacteria on starch agar to examine the...
Lesson Plan
Curated OER

Selecting Soil Organisms in Compost

For Teachers 12th - Higher Ed
Students demonstrate that many of the enzyme systems needed to break down--and therefore clean up-society's wastes already exist in nature among the decomposers. They select the best starch-munching organisms by altering the environment...
Lesson Plan
Curated OER

Cloning of Plasmid and Spinach DNA

For Teachers 12th - Higher Ed
Students ligate fragments of genomic DNA from spinach into a vector plasmid. They perform a restriction enzyme digestion. Student use a ligated DNA molecule to transform E. coli cells. Students analyze their procedures and outcome of...
Lesson Plan
Curated OER

ISOLATION OF DNA FROM ONION

For Teachers 9th - 12th
Learners perform a lab in which they extract DNA from onion cells. Students break through the cell and nuclear membranes and then break down the protein that the DNA is wrapped around.
Lesson Plan
Curated OER

ECOLOGICAL BIOASSAY OF COPPER SULFATE IN DAPHNIA MAGNA

For Teachers 9th - Higher Ed
Students use this lab as a follow up to the introduction of the ecosystems and productivity levels, bioassays and what and how they measure, and Daphnia magna as an index organism, i.e., a species whose health within an ecosystem...
Lesson Plan
Curated OER

DNA Blueprint for Life

For Teachers 6th - 8th
Students isolate DNA from different food sources. In this biology lesson, students research DNA extraction. They analyze DNA stands collected from the lab, and compare the differences between each.
Lesson Plan
Curated OER

Relationships and Biodiversity

For Teachers 7th - 12th
Students examine diversity on the planet and the differences within a species.  In this investigative lesson students complete a lab that allows students to better understand the relatedness between plants. 
Lesson Plan
Curated OER

An Introduction to Four Groups of Biologically Important Compounds

For Teachers 9th - 12th
Young scholars learn about the four biochemicals that are important biologically. For this biochemicals lesson plan, students identify the four major groups of biochemicals including carbohydrates, proteins, lipids and nucleic acids....
Lesson Plan
Curated OER

Milk Glue

For Teachers 9th - Higher Ed
Students create glue from milk by curdling milk with an acid. In this protein denaturing lesson plan, students experiment with milk and vinegar to denature the proteins in milk, create curds and whey and use the curds to produce glue by...
Lesson Plan
Curated OER

The Great Cafeteria Caper

For Teachers 11th - Higher Ed
Students extract DNA from their own hair roots. They run an electrophoresis gel to examine patterns of their DNA along with standard DNA. The experiment is based on a crime scene scenario.
Lesson Plan
Virginia Department of Education

Physical and Chemical Properties of Water

For Teachers 9th - 12th
How can you effectively provide detailed concepts of water properties to your high school class in a way they find exciting and challenging at the same time? By letting them play, of course! Through a variety of...
Lesson Plan
Curated OER

DNA on Stick

For Teachers 10th - 12th
Students experience a "hands-on" activity to get visual evidence of the physical nature of DNA and the process of DNA purification. They explore one method of chromosomal DNA isolation and DNA extraction.
Lesson Plan
Curated OER

Macro-DNA: Doing DNA Fingerprinting

For Teachers 9th - 11th
Students explore gel electrophoresis using paper models. They model DNA sequences and shade the boxes on their Gel Electrophoresis Sheet which represent the individual fragments.
Lesson Plan
Curated OER

Sea Urchin Embryology

For Teachers 11th - Higher Ed
Students explore the process of evolution. They examine examples of how homeotic genes may work and obtain gametes. Using a microscope, students observe the fertilization of sea urchins. They video tape the process and write a...
Lesson Plan
Curated OER

Pesticides and Eggshell Thinning.

For Teachers 9th - 10th
Students analyze the calcium content of egg shells as an introduction to the toxic effects of pesticides on biological systems.
Lesson Plan
Curated OER

It's All About the Roots

For Teachers 9th - 12th
Students investigate the process of hydroponic agriculture. They grow beans in different hydroponic solutions, compare results and graph their observations.
Lesson Plan
Curated OER

GenEng

For Teachers 7th - 9th
Learners investigate the process of genetic engineering. In this genetic engineering lesson plan, students use paper models of DNA and plasmid bacterium to investigate the process of replicating DNA, splicing genes from DNA, and...
Lesson Plan
Curated OER

Flesh Eating Bugs, Moldy Corpses, The Trail of a Killer

For Teachers 5th - 12th
Students read about how forensic entomologists use maggots to solve murders. In this forensic science lesson, students read an article and answer questions. They go to different websites about evidence and fingerprinting. 
Lesson Plan
Curated OER

Polymerase Chain Reaction (PCR)

For Teachers 9th - 12th
Students explore how PCR works through various activities. In this biology lesson, students explain how PCR generate copies of DNA. They simulate the process using an online interactive website.
Lesson Plan
Curated OER

Bioluminescence

For Teachers 6th - 12th
Students differentiate chemiluminescence from bioluminescence. In this biology instructional activity, students explain how fireflies and other animals emit light. They discuss the applications of engineered bioluminescence.
Lesson Plan
Curated OER

Macro-DNA: Doing DNA Fingerprinting and Gel Electrophoresis

For Teachers 10th - 12th
Students create numbered DNA sequences by taping together the order of the sequence. They count the number of bases in their RFLP's and shade the boxes on their Gel Electrophoresis sheets that represent individual fragments. They...
Lesson Plan
Curated OER

DNA Fingerprinting with Gel Electrophoresis

For Teachers 9th - 12th
Students use DNA fingerprinting to demonstrate the concept that DNA fingerprinting can be used to identify individuals and solve problems. They use gel electrophoresis to analyze the DNA of a suspected criminal to prove innocence or guilt.

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