Wikipedia: National Historic Landmarks in Pennsylvania: Carlisle Indian School

Associated with French and Indian War.

A home of Johann Conrad Weiser, who enlisted the Iroquois on the British side of the French and Indian War.

Frank Lloyd Wright designed it. The American Institute of Architects and National Trust for Historic Preservation commented upon it.

A home of Matthew Stanley Quay, a Republican National Chairman who was campaign manager for Benjamin Harrison's successful presidential campaign.

Stately home of chemist Joseph Priestley, who, disenchanted with England moved here in 1794 and continued his ground-breaking research.

The first railroad tunnel in the United States. Regarded as an engineering marvel.

A studio of Wharton Esherick who participated in Arts and Crafts Movement.

Possibly the only remaining German Weinbauernhaus in America, combining a residence with the production of alcohol.

House built in parts by owner William Stiegel and then by Robert Coleman.

Located in what is now Tulpehocken Creek Park.