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This Virtual Lab: Determining the pKa and Concentration Ratio of a Protein in Solution interactive also includes:
It's pretty common to determine the dissociation constant for an acid or a base ... but, what about a protein? Challenge your class with a virtual lab designed to further develop their acid-base chemistry skills. Individuals determine the protein's dissociation constant as well as the protein's concentration ratio.
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CCSS:
Adaptable
Concepts
Additional Tags
Instructional Ideas
- Make the resource a summative assessment for an acid-base chemistry unit
- Add a real-world element to the lab by introducing the uses of protein dissociation constants and how they relate to ligand binding by assigning a scholarly article
Classroom Considerations
- The lab is a bit on the difficult side—make sure pupils are prepared!
Pros
- The Virtual Stockroom offers an amazing selection of acids and bases to choose from
- Solutions are easily mixed and discarded, allowing users to stay organized throughout the lab
Cons
- None