Long strings of amino acids fold themselves into stable peptides. The simulation allows scholars to observe the process in multiple ways. Using hydrophobic, hydrophilic, or a combination of proteins in three different solutions, the folding of peptides begins to make sense.

Concepts

protein, hydrophobia, hydrophilia

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Additional Tags

science

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Instructional Ideas

• Connect the vocabulary words to the root words
• Create proteins that are all hydrophilic, all hydrophobic, and a mixture of both

Classroom Considerations

• Relies on prior knowledge of protein synthesis, hydrophobic, and hydrophilic interactions

Pros

• Clearly shows something difficult to conceptualize
• Allows for different color coding based on charge or hydrophobicity

Cons

• None

Common Core

SL.9-10.2 SL.11-12.2 RST.9-10.4 RST.11-12.4