Mismatch Repair

What does a cell do when DNA is not copied correctly? An informative video shows budding scientists an example of a mismatch mutation during DNA replication. Viewers learn that to prevent a mutation from occurring, cells have mechanisms to repair a mismatch using exonucleases and polymerases. 

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CCSS: Adaptable
NGSS: Adaptable
Instructional Ideas

  • Introduce DNA mutation and repair systems by showing the video clip
  • Use to extend learning about DNA replication
Classroom Considerations

  • Expects students have general knowledge of DNA structure and DNA replication

  • Narrator gives a good description of the process of DNA replication
  • Visual allows scholars to see what is happening in the cell as DNA is being copied

Common Core