Howard Hughes Medical Institute
Translation (Advanced Detail)
Who said staying predictable is a bad thing? Translation follows a predictable four-step process. Scholars view a summary of each step with a breakdown of every detail, then examine different functions, highlighted with different colors,...
Serendip
From Gene to Protein via Transcription and Translation
DNA carries the codes for creating just the right protein. A well-designed lesson leads pupils through the process from start to finish and everywhere in between. Guiding questions with supporting video help scholars understand the...
Be Smart
3 Incredible Examples of Evolution Hidden in Your Body
Human traits trace back to simpler species—such as chickens, for example. Using the human genomes, scientists connect these traits to their ancestral origins. A video presentation highlights the structure of human DNA and makes a...
Curated OER
Proteins Expressed At Different Stages
Students investigate protein electrophoresis in a lab setting. Full laboratory equipment is needed and safety should be taught. The level of prior knowledge needed to perform lab is high and is ideal for an honors class.
Curated OER
Identification of Animals by Serum Electrophoresis
Learners compare their unknown serum against a set of known serum standards and determine the animal source of their serum. They write a lab report to communicate their results.
Curated OER
How Genes Work Lesson Plan
Young scholars define the key terms that are the structure and function of DNA. For this genetics lesson students complete a lab activity in which they construct a model DNA structure.
Curated OER
Enzyme Activity: An Inquiry Based Approach
Students explore biochemical reactions mediated by enzymes in an inquiry approach. They are given two questions about the types of living materials that contain the enzymes that break down hydrogen peroxide, and under what conditions the...
Curated OER
The Genetic Basis of Neurological Disorders
Young scholars explore neurological disorders. They examine the presence and absence of discernible genes. Students describe neruological diseases and draw faces of affected persons. They play a human neurology disorders learning game.
Curated OER
Enzyme Activity: An Inquiry Based Approach
Using an inquiry approach to studying biochemical reactions, cooperative teams of young scholars investigate hypotheses about living materials that contain enzymes which break down in hydrogen peroxide. They perform experiments,...
Curated OER
Bacterial Transformation
Students discuss a bacterial experiment they previously performed and complete a pre-assessment. They participate in a lecture discussion given by the teacher through PowerPoint and then complete a cartoon worksheet and post-assessment.
Curated OER
Temperature and the Tomato
You will need a photovoltaic system and monitor at your school in order to obtain all of the data required to thoroughly implement this lesson. Your class monitors daily temperature and insolation amounts over a two week span of time....
Curated OER
Blood Typing Investigation
Learners role-play a scenario in which a car crash patient is inadvertently given the wrong blood type during a transfusion. They perform blood typing and explore the genetics behind ABO and RH blood types using simulated blood.
Curated OER
The Case of Regulation in Cells
After your biologists have learned about transcription, translation, and gene regulation, they work in a small group to create a poster of a system that serves as an analogy of the gene regulation process. They share their creations with...
Curated OER
Investigating Evolutionary Questions: Bats, Whales, Reptiles, Birds, Animal Classification
Students are guided through a process in which three questions are addressed by retrieving beta hemoglobin sequences from online databases, and using online tools to compare those sequences in student-selected animals.
Curated OER
Making Cladograms
High schoolers construct cladograms (evolutionary trees), showing how shared derived characters can be used to reveal degrees of relationship. They interpret and analyze cladograms, and determine where unclassified vertebrates would fit...
Curated OER
21st Century Medicine: Nerves of Steel
Students model a sarcomere's action, they gain a kinesthetic and visual understanding of muscle contraction. They use this exercise stimulates the production of myosin and actin. Students use two colors of clay, make a "sandwich" of...
Curated OER
Genetics 5 Technology
Young scholars, after studying extraction and gel electrophoresis, recombinant DNA, transgenic organisms, and reproductive cloning, summarize the main concepts in DNA technology. They analyze the applications of DNA: forensics, medicine,...
Curated OER
Demonstration of Cheese-Making Enzyme Magic
Students participate in a modified demo enzyme lab, a "magic show." The purpose of the demo is to tickle the curiosity of the student and grab their interest before discussions of enzymes. Its purpose is also to stimulate problem solving...
Curated OER
Implications of the Human Genome Project
Students study the Human Genome Project through classroom discussion and the video, Cracking the Code of Life. They research reports about the issues of disease, human health, and the ethical, legal, and societal implications of the...
Curated OER
Food For Thought
Students examine their school population about their health and exercise patterns. They brainstorm a list of factors that influence people to eat the way they do.
Curated OER
Who am I and Why?
Students make comparisons about themselves and others, which are real and meaningful. They study some basic concepts in the area of genetics and do a complimentary series of experiments, or explorations that illustrate these concepts
Curated OER
Creating an Enzyme-Substrate Model
Students explore the reaction rates of an enzyme-mediated reaction through experimentation. In small groups, they use everyday objects to demonstrate the effects of environmental variables on enzyme function.
Students graph and...
Curated OER
Macro-DNA: Doing DNA Fingerprinting
Students explore gel electrophoresis using paper models. They model DNA sequences and shade the boxes on their Gel Electrophoresis Sheet which represent the individual fragments.
Curated OER
Indirect Observation
Students observe obscertainers through indirect observations and make hypotheses about the internal wall structures of the containers. In this indirect observation lesson plan, students make observations of 4 obscertainers with a steel...
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