Cold Spring Harbor Laboratory
The RNA Message Is Sometimes Edited
In 1993, Phillip Sharp and Richard Roberts won the Nobel Prize for their discovery of split gene theory. Learn about the breakthrough with the help of an online interactive. Hear both scientists explain it in their own words, watch an...
Curated OER
Constructing a Protein Sentence
Fourth graders, in pairs, examine how every cell contains a 'blueprint' coded in DNA molecules. They use a DNA template to determine the m-RNA and t-RNA sequences for protein.
Curated OER
Genetic Technology
In this genetic technology worksheet, learners will answer 6 true or false statements and 4 short answer questions based on the mapping and sequencing of the human genome and the applications of the Human Genome Project.
Curated OER
Genetic Challenge Worksheet
In this genetics worksheet, students describe how to tell the difference between DNA, RNA, and proteins. Students also learn about the processes of transcription and translation. This worksheet has 3 short answer and 3 fill in the blank...
Serendip
From Gene to Protein - Transcription and Translation
Learners identify the different steps involved in DNA transcription. In this genetics instructional activity, pupils complete a worksheet and model the translation process with a paper chain activity. They watch a video on sickle cell...
Curated OER
Nucleic Acid
In this chromosome activity students complete a crossword puzzle by answering questions on DNA, nucleic acids, nucleotides and RNA. Â
Curated OER
Gene Regulation Mechanisms
Students explore genetics. They discuss how chromosomes and/or genes are regulated during the life of an organism. In a lab setting, students compare and contrast the genomic regulation of prokaryotic and eukaryotic cells using...
Curated OER
Using VNTR Analysis to Identify Guilt at a Crime Scene
Students collect DNA from cheek cells. They compare and contrast the processes of DNA replication and PCR. They discuss how this information can be used to determine guilt at crime scenes.
Curated OER
"Who Done It?" Analysis of Molecular Fingerprints Left At the Scene of the Crime
Learners examine different types of DNA fragments. They record and analyze their results. They determine who is the criminal in the story.
Curated OER
Molecular Evidence for Evolutionary Relationships
Learners compare the amino acid sequences in cytochrome-c for a variety of organisms and use this information to infer evolutionary relationships. Students investigate the role of homeobox genes and what this indicates about the...
Curated OER
Sets of Chromosomes
In this chromosome learning exercise, students answer eighteen questions about chromatids, chromosomes, types of reproduction, haploid and diploid cells and zygotes.
Curated OER
Sequencing the Cystic Fibrosis Gene: A Simulation
Ninth graders determine nucleotide sequences. They identify those base sequences that are normal, those that are normal variants and those that cause cystic fibrosis. Students use DNA nucleotide sequences to determine amino acid...
Curated OER
DNA and Genes
Students analyze the structure of DNA. They describe how the structure of DNA enables it to reproduce itself accurately. Students discuss genes and the sequence of nucleotides occur in DNA.
Curated OER
DNA and Genes
In this DNA worksheet students will label the 6 parts that make up DNA and review the process of replication of DNA. This worksheet has 6 matching and 5 fill in the blank questions.
Curated OER
Ghost in Your Genes
Students explore DNA microarrays. In this genetics lesson, students model DNA microarrays that are used by scientists. Students work to determine levels of breast cancer genes in patients. They will determine the treatment required based...
Curated OER
Embryology as Evidence of Evolution
Students observe the two major developmental pathways (protostome and deuterostome). They analyze data regarding differences in nucleotide sequences and construct a phylogenetic tree. They observe the similar evolutionary history shared...
Curated OER
Pliable Proteins
Students make models of protiens using wire and paperclips. They are given step by step instructions with lots of information about proteins throughout the directions. They make the three basic structual elements of proteins;...
Curated OER
Regulating Gene Expression
In this gene expression worksheet, students read about two transcription factors: activators and repressors. Students complete 1 multiple choice and 5 short answer questions.
Curated OER
Teaching Biology Through Bioinformatics
Wow! A very detailed slideshow covers complex topics of genome research methods. This is advanced and relevant to the highest level of school biology. Excellent resource if you wish to expose your class to scientific methods and...
Concord Consortium
Modeling Translation
An mRNA sequences make proteins, the most common molecules in cells. Young scientists observe translation of mRNA on ribosomes. They view them forming amino acids. Finally, the amino acids curl into proteins.
Curated OER
Cracking the Genetic Code
Students examine an article, "Genome 'Treasure Trove'" and participate in a class discussion prior to researching further information in order to write their own feature article on the Human Genome Project.
Curated OER
Genetics
In this worksheet, students will answer 4 fill in the blank statements about Mendelian inheritance and meiosis. Then students will use Punnett squares to answer three short answer questions. Students will match 8 genetics vocabulary...
Curated OER
Labs on A Chip
Students are introduced to DNA microarrays. They discuss how scientists and doctors use them and how they work. They complete a worksheet and discuss their findings.
Curated OER
DNA Fingerprinting
Pupils experiment with chromatography as a technique which is similar to electrophoresis that scientists use to identify DNA samples.