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Curated OER
Antibodies
High schoolers conduct a series of exploration activity on how vaccines and antibodies work. In this biology lesson, students test how antigens and antibodies work in the body. They discuss the benefits of vaccines in promoting immune...
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Antigens versus Antibodies "KO'd in Round Three" The Third Line of Defense of the Human Immune System
Seventh graders investigate antibodies, as the body's third line of defense against disease. They discover why antibodies do not defend the body against viruses and create a pantomime of the antibody/antigen/HIV relationship.
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Antigens
Students examine antigens including ones found in humans. For this immune lesson students complete several experiments in relation to antigens and antibodies.
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Teaching Multiple Alleles
High schoolers view a simple ABO blood system for the introduction of this subject using concrete models of eythrocytes (red blood cells, or RBC's), antigens, and antibodies. They can physically see the antigens that result from certain...
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Molecular Recognition and the Immune Response
Students explore the importance of molecular shape and charge in molecular-recognition. They examine the interaction between antigens and antibodies. Students design and build 3-D visual models to represent molecular-recognition...
Children’s Hospital of Philadelphia
Development of Disease and Infection
It's all in the cards. Using cards to simulate a disease's attack on the immune system, pupils develop an understanding of how the immune system and pathogens react to each other and why at times the pathogen wins. Groups play a game to...
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Multiple Alleles
Students observe models of the ABO blood system including erythrocytes, antigens, and antibodies. They investigate the antigens that result from certain allele combinations and move antibodies to determine whether agglutination occurs...
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Antibodies and Antigens: Fitting Together
Using basic matching, aspiring biologists connect types of antigens with the antibodies that fight them. Provide ample instruction prior to assigning this one-sheet resource. Require students to explain in writing how each antibody works...
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Disease Diagnosis
Learners comprehend how biotechnology can be used to diagnose infectious disease such as protein technologies vs. DNA technologies. They comprehend procedure and uses of PCR, Western Blot, and ELISA as diagnostic tools. Students know how...
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Antibody and Antibody Specificity The Egg Mishap
Learners investigate a set of foods to find the presence of eggs after designing an experiment that will complete the test. They complete a test and discuss antibody-antigen specificity.
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Anatomy and Physiology Study Questions on Immunology
For this anatomy and physiology study question worksheet, students define 20 terms related to the immune system. They answer 19 short answer questions that deal with immunology, autoimmune diseases, and the components and cells related...
Children’s Hospital of Philadelphia
The Adaptive Immune System
Attack the pathogen from within. Learners delve deeper into the immune system and find out about the adaptive immune system such as T and B cells. Groups create graphical models of the adaptive immune system along with a multimedia...
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Common Vaccinations
Students examine vaccinations and how they work. In this vaccinations lesson students create posters that describe the various types of vaccines.
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A Pox No Longer Upon Us
Tenth graders research the development and use of vaccines. They examine historical documents for qualitative observations and the basis of immunization. They examine primary and secondary immune responses as they relate to the...
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Student Investigation on the Immune System and Hemeagglutination
Students perform an experiment to demonstrate the principles of antibody-antigen binding, the secondary immune response, cross reactivity, and complement fixation. The materials to be used include antibodies from a rabbit that was...
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Body Battles!
Seventh graders explain the role of white blood cells in fighting infections. For this life science lesson, 7th graders create flow charts showing the immune response process. They act out and play a game to simulate actions of the...
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Standard 4-Photosynthesis, Diseases and the Immune System
In this photosynthesis, disease and Immune System worksheet, students fill in the blanks with key terms to complete sentences about the transfer of energy from the sun to plants, enzymes as catalysts in reactions, homeostasis, the immune...
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The Genetics of Antibody Diversity
Students distinguish between the light and heavy chain sections. In this biology lesson plan, students simulate the DNA splicing process. They calculate antibody diversity using the information given.
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Food Forensics: A Case of Mistaken Identity
Ninth graders explore the specific reaction between an antigen and the antibody that recognizes it. They carry out an exploratory experiment leading to the concept of specificity.
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Using Blood Tests to Identify Babies and Criminals
Students solve a crime by matching a suspect's blood type to physical evidence collected at the crime scene. In this forensic science lesson, students identify the different blood types. They explain how blood tests work.
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Pre-Hardy-Weinberg
Learners examine the inheritance of ABO blood groups. In this investigative lesson students perform a lab and show how natural selection can alter the gene frequencies in a population.
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Operation Anitbody
High schoolers identify the types of cells that are important in the immune system. They investigate the different mechanisms used by white blood cells as they protect the body from foreign invaders. Students are given five case...
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Your Body's Defenses When Microbes Attack
Students study how being exposed to a harmful microbe doesn't automatically make them ill. They discover the lines of defense against microbe invaders and explore the roles of skin and mucus membranes, white blood cells, and lymphocytes...
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Investigating the Method by Which the Body Defends Against Pathogens
Students explore disease caused by bacteria and viruses, how they are transmitted, and how they exert their effects on their hosts. They explain how diseases, such as AIDS, are spread by exponential growth.