Using basic matching, aspiring biologists connect types of antigens with the antibodies that fight them. Provide ample instruction prior to assigning this one-sheet resource. Require students to explain in writing how each antibody works...

Students examine antigens including ones found in humans.  In this immune lesson students complete several experiments in relation to antigens and antibodies.

Learners view a simple ABO blood system for the introduction of this subject using concrete models of eythrocytes (red blood cells, or RBC's), antigens, and antibodies. They can physically see the antigens that result from certain...

Seventh graders investigate antibodies, as the body's third line of defense against disease. They discover why antibodies do not defend the body against viruses and create a pantomime of the antibody/antigen/HIV relationship.

Students comprehend how biotechnology can be used to diagnose infectious disease such as protein technologies vs. DNA technologies. They comprehend procedure and uses of PCR, Western Blot, and ELISA as diagnostic tools. Students know how...

In the preceding lesson from the unit, beginning biologists discovered that microorganisms are everywhere, so the question follows, why are we not sick all of the time? Class members read and discuss an article in small groups about...

Students explore the importance of molecular shape and charge in molecular-recognition. They examine the interaction between antigens and antibodies. Students design and build 3-D visual models to represent molecular-recognition...

Students conduct a series of exploration activity on how vaccines and antibodies work. In this biology activity, students test how antigens and antibodies work in the body. They discuss the benefits of vaccines in promoting immune...

In this simulation activity, young biologists examine blood types to determine whether the death rate in a hospital was caused because of incorrect identification of patient blood types. You will need obtain and follow the procedures of...

Students identify the types of cells that are important in the immune system. They investigate the different mechanisms used by white blood cells as they protect the body from foreign invaders. Students are given five case studies,...

Ninth graders explore the specific reaction between an antigen and the antibody that recognizes it. They carry out an exploratory experiment leading to the concept of specificity.

Seventh graders explain the role of white blood cells in fighting infections. In this life science instructional activity, 7th graders create flow charts showing the immune response process. They act out and play a game to simulate...

Students examine the inheritance of ABO blood groups.  In this investigative lesson students perform a lab and show how natural selection can alter the gene frequencies in a population.

High schoolers model how the malaria-causing protist avoids immune response in its host. In this parasite biology lesson, students use printed cell images to model the way that Plasmodium changes surface protein markers every few...

Students solve a crime by matching a suspect's blood type to physical evidence collected at the crime scene. In this forensic science lesson, students identify the different blood types. They explain how blood tests work.

Young historians view and analyze photos and documents from WWII that are related to blood transfusions and blood plasma. A demonstration of correct and incorrect blood donors visually shows the importance of knowing blood...

Students perform an experiment to demonstrate the principles of antibody-antigen binding, the secondary immune response, cross reactivity, and complement fixation. The materials to be used include antibodies from a rabbit that was...

A very timely lesson looks at the social and political factors that affect the spread of disease. Using the 1918 Influenza Pandemic as a case study, pupils research factors that influenced the spread of the disease, including the role of...

Attack the pathogen from within. Learners delve deeper into the immune system and find out about the adaptive immune system such as T and B cells. Groups create graphical models of the adaptive immune system along with a multimedia...

It's all in the cards. Using cards to simulate a disease's attack on the immune system, pupils develop an understanding of how the immune system and pathogens react to each other and why at times the pathogen wins. Groups play a game to...

Learners observe models of the ABO blood system including erythrocytes, antigens, and antibodies. They investigate the antigens that result from certain allele combinations and move antibodies to determine whether agglutination occurs...

Students develop an experiment to test a hypothesis. They use their knowledge of antigen-antibody specificity to develop a hypothesis. Students articulate that the antibody-antigen specificity is one part of the immune system. They...

Students investigate a set of foods to find the presence of eggs after designing an experiment that will complete the test. They complete a test and discuss antibody-antigen specificity.

Students identify the different kinds of blood. In this biology lesson, students investigate the antigens, agglutinins and Rh factor using their own blood. They use Punnett squares to predict blood type of offspring.