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Lesson Plan
Curated OER

Extraction of DNA from White Onion

For Teachers 9th - 12th
Students conduct lab test with minced onion to determine where chromosonal DNA is located within the cell, and whether or not it can be extracted.
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Lesson Plan
Curated OER

DNA Extraction From Living Things

For Teachers 9th - 10th
Students extract DNA from split peas. In this biology lesson, students hypothesize what DNA looks like and perform the experiment to verify their hypothesis. They explain the importance of DNA in living things.
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Lesson Plan
Curated OER

Cloning of Plasmid and Spinach DNA

For Teachers 12th - Higher Ed
Young scholars ligate fragments of genomic DNA from spinach into a vector plasmid. They perform a restriction enzyme digestion. Student use a ligated DNA molecule to transform E. coli cells. Students analyze their procedures and...
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Lesson Plan
Curated OER

Teaching the Chemical and Structural Properties of DNA

For Teachers 9th - 12th
Students work together to answer questions about DNA. They identify where DNA is found and its function in the cell. They note any physical similarities they have with their family members
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Lesson Plan
Curated OER

The Cloning of Plasmid and Spinach DNA

For Teachers 10th - 12th
Young scholars will first extract genomic DNA from spinach and perform a restriction enzyme digestion on both the spinach DNA and the plasmid using the same restriction enzyme. They then ligate the cut plasmid DNA with the cut spinach...
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Lesson Plan
Curated OER

Comparison of Four-, Six-, And Eight-bp Cuts in Calf Thymus Dna

For Teachers 9th - 12th
Young scholars investigate the use of restriction enzymes to recognize a four-, six-, and eight-nucleotide sequence. They utilize restrictive endonucleases to cut Thymus DNA and compare results by viewing the DNA fragments on Agarose Gel...
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Lesson Plan
Curated OER

What Happens When A Cell Divides?

For Teachers 9th - 12th
Students investigate the cycle of mitosis. In this biology lesson, students discuss the different stages of mitosis through cell reproduction. They further their investigation through laboratory analysis.
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Lesson Plan
Curated OER

DNA Fingerprinting through a Chemistry Lens

For Teachers 6th - 12th
Young scholars explore DNA and restriction enzymes using fragments of DNA separated by electrophoresis on an agarose gel. They analyze the results to see "whodunit".
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Lesson Plan
Curated OER

PROTOPLAST PRODUCTION

For Teachers 9th - 12th
Students are allowed to strip away the cell walls of plants cells (using enzymes) and then observe the resulting spherical protoplasts (plant cells minus the cell wall). They see that plants cells indeed have a plasma membrane in...
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Lesson Plan
Curated OER

Designer Genes

For Teachers 9th - 12th
Learners view a video on DNA. They discuss mitosis, meiosis and fertilization. They use strips of paper to simulate fertilization and analyze the genotype and phenotype of the combined chromosomes.
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Lesson Plan
Curated OER

Phenotypic and Genotypic Changes in Bacteria

For Teachers 11th - 12th
Students investigate a rapid method to render the bacterium Escherichia coli "competent" to uptake plasmid DNA. They demonstrate the phenotypic changes associated with transformation. They perform a cell resuspension from the...
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Lesson Plan
Curated OER

How Genes Work Lesson Plan

For Teachers 9th - 12th
Students define the key terms that are the structure and function of DNA. In this genetics lesson students complete a lab activity in which they construct a model DNA structure.
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Lesson Plan
Curated OER

Constructing a Protein Sentence

For Teachers 4th
Fourth graders, in pairs, examine how every cell contains a 'blueprint' coded in DNA molecules. They use a DNA template to determine the m-RNA and t-RNA sequences for protein.
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Lesson Plan
Curated OER

2D Animation of Cellular Processes

For Teachers 9th - 10th
Students create an animation of a cell process and insert it into a presentation. They choose a cellular process such as mitosis, osmosis or DNA replication, and create a simple 2D animation.
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Lesson Plan
Serendip

From Gene to Protein - Transcription and Translation

For Teachers 9th - 12th Standards
Learners identify the different steps involved in DNA transcription. In this genetics instructional activity, pupils complete a worksheet and model the translation process with a paper chain activity. They watch a video on sickle cell...
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Lesson Plan
Curated OER

Gene Regulation Mechanisms

For Teachers 11th - Higher Ed
Students explore genetics. They discuss how chromosomes and/or genes are regulated during the life of an organism. In a lab setting, students compare and contrast the genomic regulation of prokaryotic and eukaryotic cells using...
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Lesson Plan
Curated OER

Homologous Shoes

For Teachers 10th - 12th
Students examine the concept of homology by observing their shoes and those of their classmates. They summarize the observations of everyone's shoes relating it to chromosomes in cells. They share their observations with the class.
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Lesson Plan
Curated OER

"Who Done It?" Analysis of Molecular Fingerprints Left At the Scene of the Crime

For Teachers 9th - 12th
Learners examine different types of DNA fragments. They record and analyze their results. They determine who is the criminal in the story.
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Lesson Plan
Curated OER

Using VNTR Analysis to Identify Guilt at a Crime Scene

For Teachers 9th - 12th
Students collect DNA from cheek cells. They compare and contrast the processes of DNA replication and PCR. They discuss how this information can be used to determine guilt at crime scenes.
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Lesson Plan
Curated OER

Onion Skins

For Teachers 2nd - 6th
Students explore the structure of a plant cell. They carefully peel a single layer of onion skin from a slice of onion and stain it with methylene blue to observe the structures inside. They use a Digiscope connected to a computer to...
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Lesson Plan
Curated OER

Genes

For Teachers 7th - 12th
Students explore the history, inheritance and mutations of genetics.  In this genetic lesson plan students complete experiments on DNA sequences.
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Lesson Plan
Curated OER

Using Yeast as an Ultraviolet Light Measurement Tool

For Teachers 9th - 12th
Students accurately measure the relationship between radiation dose and either survival or some genetic event such as mutation or recombination. They investigate the damage that was done to the DNA molecule as a result of exposure to...
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Lesson Plan
Curated OER

ISOLATION OF DNA FROM ONION

For Teachers 9th - 12th
Learners perform a laboratory exercise designed to show how DNA can easily be extracted from onion cells. They conduct an optional test for the presence of DNA using standard lab equipment.
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Lesson Plan
Curated OER

How is Foreign DNA Inserted into Organisms During the Genetic Engineering of Crops?

For Teachers 11th - 12th
Students examine the positive benefits and negative consequences of genetically modified organisms following a lecture covering key biotech concepts and techniques. Students then conduct and experiment comparing the travel rate of...

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