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Lesson Plan
Curated OER

Producing a Strain of E. coli that Glows in the Dark

For Teachers 8th - 12th
Students observe the experimental process called bacterial transformation and demonstrate phenotype changes in bacteria that have been transformed with an antibiotic-resistance gene and a metabolic marker. They create a luminescent...
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Lesson Plan
Curated OER

Characterization of the Bioluminescence (Lux+) Gene E. coli

For Teachers Higher Ed
Students grow E. coli strain HB101, which contains the plasmid pUCD607 with the bioluminescence (Lux+) gene. The plasmid containing the Lux+ gene is isolated from the E. coli, then characterized by restriction analysis.
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Lesson Plan
Curated OER

E. coli and Their Human Environment

For Teachers 9th - 12th
Students are able to observe how environmental changes (antibiotics) affect the growth of E. coli. They are able to use the "F" test for statistical analysis. Students can explain that E. coli is a common rod-shaped intestinal...
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Lesson Plan
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Curated OER

How Safe is that Fresh Autumn Cider?

For Teachers 11th - 12th Standards
Corn stalks and pumpkins, caramel apples and cider, falling leaves and brisk nights. There are a few of autumn's favorite things. But how safe is that unpasteurized cider bought at the roadside stand? Young researchers investigate the...
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Lesson Plan
Centers for Disease Control and Prevention

Microbe Multiplication Magic

For Teachers 6th - 8th Standards
A lesson plan introduces the reproduction rate of E. coli though a video. Then scholars complete a data table and graph of reproduction rates in ideal conditions as well as less than ideal conditions. 
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Lesson Plan
Curated OER

Viewing Bacteria

For Teachers 9th - 12th Standards
Have you ever wanted to know the true structure of E.coli? Does the thought of peering into its "small world" sound exciting? Here is a lesson that allows pupils the ability to do just that. Blossoming microbiologists use microscopes to...
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Lesson Plan
Curated OER

Transformation of E. coli with Antibiotic Resistance

For Teachers 9th - 12th
High schoolers participate in an experiment in which they transform an E. coli cell. They discover how the genetic make-up of the cell can be changed by added foreign DNA. They answer questions to complete the lab.
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Lesson Plan
Curated OER

Antibiotic Resistance in E. coli

For Teachers 9th - 12th
Students discuss the antibiotic resistance of bacteria. They design an experiment to test the resistance of different strands of E. coli. They answer discussion questions to end the lesson plan.
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Lesson Plan
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Nemours KidsHealth

Food Safety: Grades 9-12

For Teachers 9th - 12th Standards
Food poisoning, salmonellosis, E. Coli, shigellosis, tapeworms—all these words can strike fear into eaters. Alas, the five-second rule is not necessarily true! Two activities teach teens safety rules for food purchasing, preparation,...
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Lesson Plan
Curated OER

Bacterial Transformation: Laboratory Experiment

For Teachers 9th - 10th
Young scholars participate in a group lab in which they complete the process of bacterial transformation. If lab procedures are followed correctly, Students see their results in a few days...bacteria glowing green.
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Lesson Plan
Curated OER

E.coli and their Human Environment

For Teachers 9th - 12th
Pupils observe how environmental changes (antibiotics) can affect the growth of E.coli, the rod shaped intestinal bacterium. They use the "F" test for statistical analysis. Students
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Lesson Plan
Curated OER

Breaking News English; Deadly E. Coli Strikes Europe

For Teachers Pre-K - 7th
Read a breaking news article relating to a deadly bacteria while  building vocabulary and writing skills. Critical thinkers work with a partner to write down the different words they have found in the article. They complete several...
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Lesson Plan
Curated OER

Viewing Bateria

For Teachers 9th - 12th
Students use microscopes to observe E. coli bacateria on prepared slides and in a live culture. They use micro-slide viewers to observe the shapes of various bacteria and the structures within the bacterial cell. Students make an...
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Lesson Plan
Curated OER

Mutations--Preexisting or Acquired?

For Teachers 9th - Higher Ed
Students explore the reasoning and experimental approaches to mutations. They expose a culture of E. coli to virulent bacteriophage and observe whether mutations of the cells existed previously or if the bacteria mutated as a response...
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Lesson Plan
NOAA

Watch the Screen!

For Teachers 9th - 12th
Can a sponge cure cancer? Life science pupils visit the drugstore under the sea in the fifth activity of six. Working groups research the topic then get hands-on experience by testing the inhibiting effects of several plant extracts on...
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Worksheet
Curated OER

Challenges of Sampling

For Students 9th - Higher Ed
For this sampling worksheet, students try different sampling methods to determine which is the best for determining contamination on a substance. This worksheet has 5 short answer questions.
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Lesson Plan
Curated OER

The Bacteria Time Bomb in your Home

For Teachers 4th - 6th
Students read an article that explains the dangers of household bacteria. In this instructional activity, students explore items in a home that easily hold bacteria, then complete several activities to reinforce comprehension of the...
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Lesson Plan
Curated OER

Teaching Biotechnology With Models

For Teachers 7th - 12th
Students are introduced to biotechnology by using models. The teacher uses A Sourcebook of Biotechnology Activities, Rasmussen and Matheson project co directors. One of the activities in the book is: students use a scale models to very...
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Lesson Plan
Nuffield Foundation

Following Gene Transfer by Conjugation in Bacteria

For Teachers 9th - 12th
After the lab, you'll be able to solve this analogy: Natural selection is to vertical transfer of genes as ___ is to the horizontal transfer of genes. Young biologists conduct an experiment on E. coli bacteria to explore the process of...
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Lesson Plan
Towson University

Transformation Lab

For Teachers 9th - 12th Standards
Transform your class' understanding of genes and antibiotic resistance with the Transformation Lab. Junior geneticists create and observe their own resistant strains of E. coli through research, discussion, and experimentation. The...
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Lesson Plan
Curated OER

Sociobiology: Heredity Factors

For Teachers 9th - 12th
Students examine DNA replication and how proteins are synthesized from DNA codes and continue to explore the effects of genetics in additional lessons. Among the topics covered are: protein synthesis, cell chemistry, environmental...
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Lesson Plan
Curated OER

Cloning And b-Galactosidase

For Teachers 10th - 12th
Students investigate cloning using E coli cultures. Through laboratory exercise, they determine if E coli cells contain b - galactosidase.
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Worksheet
Curated OER

Geometric Sequences - Bacterial Growth

For Students 8th - 10th Standards
Bring algebra to life with scientific applications. Math minded individuals calculate and graph the time it takes a bacterium to double. They discuss geometric sequences and use a chart to graph their findings. There are 38 questions all...
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Lesson Plan
National Research Center for Career and Technical Education

Safety and Sanitation

For Teachers 9th - 12th Standards
Your microbiologists explore the graphing of exponential growth functions using bacteria, like e. coli and salmonella, in a well-written, career and technology lesson. 

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