Howard Hughes Medical Institute
DNA Sequence Assembly
Oncologists use DNA sequence data to identify specific cancers and offer more targeted treatments. Grasp an understanding of the complexity involved by learning how the body sequences and assembles DNA. Eager scientists explore the...
Curated OER
Constructing a Phylogenetic Tree Using DNA Sequence Data
Students analyze DNA sequence differences between organisms in order to establish a reasonable picture of the evolutionary relationships between them. They take the role of molecular biologists and make genetic changes and constructing...
Curated OER
Regents High School Examination: Living Environment 2005
The 2005 version of the Regents High School Examination in the area of ecology is as comprehensive as previous years' exams. It consists of 40 multiple choice questions on everything from the structure of DNA to the interactions within...
Howard Hughes Medical Institute
Using DNA to Explore Lizard Phylogeny
In a fun and interactive two-day lesson, learners sort anole lizard pictures by appearance. Next, they watch a video about the anoles and re-sort based on the information in the video. In addition to physical characteristics, budding...
Howard Hughes Medical Institute
DNA Profiling Activity
Everyone loves a good mystery ... can your class actually solve one? Partnered pupils take on the role of forensic investigators during a three-part activity focusing on DNA evidence processing. Learners discover the methods used to...
Curated OER
Pseudogene Suite
Students use Biology Workbench to explore DNA sequence data for the GULOP gene in humans, chimpanzees, orangutans, and crab-eating macaques and the beta globin gene and its pseduogene in humans, gorillas, and chimpanzees.
Serendip
UV, Mutations, and DNA Repair
How effective are cells at repairing UV damage? An inquiry-based lesson has learners experiment with organism by exposing them to various levels of UV light and then examining their DNA after a period of time. Pupils test different...
Curated OER
Cut-off Genes
Investigate the relationships between different deep-sea organisms by DNA sequencing. A worksheet provides instructions for DNA sequencing and space to work. They simulate gel electrophoresis by cutting out paper "DNA strands." Modeling...
Virginia Department of Education
DNA Structure, Nucleic Acids, and Proteins
What is in that double helix? Explain intricate concepts with a variety of creative activities in a lesson that incorporates multiple steps to cover DNA structure, nucleic acids, and proteins. Pupils explore the history of DNA structure,...
Curated OER
DNA, RNA, Protein Synthesis, & Mutation
In this biology worksheet, students identify and label the diagram shown by stating what each part of the diagram represents on the line. Then they use the DNA strand as the original strand and complete the data table. Students also...
Curated OER
What Can Pseudogenes Tell Us About Common Ancestry?
Students compare/constrast DNA sequence data for a portion of the rat GULO gene to the corresponding sequence in the inactive GULO gene in humans, chimpanzees, orangutans, and crab-eating macaques by identifying the shared sequences in...
Curated OER
DNA Fingerprints
Students interpret different DNA fingerprints, then do a jigsaw activity to explore other uses of DNA forensics. They listen to a radio program about using DNA as evidence and discuss the limitations of and problems with DNA testing.
Curated OER
DNA Chips
High schoolers explore issues surrounding DNA microarray technology. They focus on a single area of biomedical research to help them explain how science, people, ethics, and history all fit together. They analyze gene-expression data.
Curated OER
DNA Chips
High schoolers discover what they need to know about DNA chips. They extend this knowledge to analyze gene expression data to diagnose two kinds of leukemia.
Curated OER
DNA Code
Students synthesize information gathered from the web on reading the DNA code. In this upper-level biology lesson, students use an online resource to gain information about DNA codes and then create posters on what they have learned....
Curated OER
Using Amino Acid Sequences to Show Evolutionary Relationships
Junior biologists compare the amino acid sequences from fragments of five different globin molecules. They count the letter differences between each species pair. They construct a graphic representation of the evolutionary relationships...
Curated OER
Enhancing Students' Problem-Solving Abilities
High schoolers analyze the results of a hypothetical cloning experiment using a restriction endonuclease map obtained from an on-line data source. They answer the question, "How can I tell if the DNA I have obtained from this...
Howard Hughes Medical Institute
Ebola: Disease Detectives
How did the Ebola virus first infect humans? Young virologists examine genetic sequences from the 2014 Sierra Leone outbreak to find similarities during a riveting activity. Following similar methods used by MIT and Harvard, partners...
Curated OER
Using Amino Acid Sequences to Show Evolutionary Relationships
Compare protein fragments, count amino acids, and use the information to explore common ancestry. The resource mentions a student worksheet, however, a separate printable worksheet is not provided. The exercises are written into the...
Curated OER
Island Biogeography and Evolution: Solving a Phylogenetic Puzzle With Molecular Genetics
Students engage in solving a logic problem based on real organisms and real data. They develop phylogenies for seven related populations of lizards living on the Canary Islands.
Curated OER
Who Ate The Cheese?!
In this crime scene investigation worksheet, students simulate DNA sequencing and DNA restriction analysis using paper strips of DNA. Students compare the crime scene DNA to the suspects and determine who is guilty.
Towson University
Case of the Crown Jewels
Can your biology class crack the Case of the Crown Jewels? Junior forensics experts try their hands at DNA restriction analysis in an exciting lab activity. The activity introduces the concept of restriction analysis, teaches pipetting...
Towson University
The Wildlife Forensics Lab
Can science put an end to the poaching of endangered species? Show your young forensic experts how biotechnology can help save wildlife through an exciting electrophoresis lab. Grouped pupils analyze shark DNA to determine if it came...