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Activity
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Teach Engineering

Chromatography Lab

For Teachers 7th - 9th Standards
Groups use alcohol and chromatography paper to separate the color components of black ink. The purpose of the activity is to allow the class to become aware that mixtures exist in hidden places. 
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Lesson Plan
Oregon State

Using Paper Chromatography

For Teachers 9th - 12th Standards
Through the analysis of paper chromatography to separate ink from the pen found at the crime scene, learners analyze the different stains and through calculations determine the thief. 
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Lesson Plan
Curated OER

#13 Chromatography is a Gas: An Inquiry-Based Introduction to Gas Chromatography

For Teachers 11th - Higher Ed
Advanced chemistry scholars read about gas chromatography as a means of separating mixtures into their components. Then they try the technique on fingernail polish remover. Detailed instructions are provided via a lab sheet for your...
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Lab Resource
Pingry School

Liquid Chromatography

For Students 9th - 12th
A hands-on experiment applies chromatography to separate both the colors and components of grape-flavored Kool-Aid. Performing two separate activities, learners first use chromatography to divide the colors. The second activity results...
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Lesson Plan
Curated OER

Chromatography Lab

For Teachers 6th - 7th
Students discover the components of primary and secondary colors. For this physical science lesson, students create a set up in which water will separate a color into the component colors along a piece of filter paper. Students will then...
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Lesson Plan
Olomana School

Mixtures and Solutions: Paper Chromatography Experiment

For Teachers 7th - 12th Standards
Why does some ink bleed through paper, and other ink doesn't? Practice some paper chromatography to separate the colors from a pen with an interactive experiment for middle and high schoolers. Learners use a variety of solutions to track...
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Lesson Plan
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Sunlight Cal-Tech

Chromatography of Plant Pigments

For Students 9th - 12th Standards
Through a hands-on activity, an acetone-spinach solution is pre-made and learners use this solution to separate the pigments found in spinach using chromatography. The comprehensive resource includes an analysis and conclusion questions.
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Lesson Plan
LABScI

The Separation Lab: Candy Colors

For Students 9th - 12th
There's no better motivator than candy! An engaging activity has pupils explore methods for separating mixtures. A two-part lab first explores methods of separation based on size and magnetism. The second activity introduces learners to...
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Lesson Plan
Curated OER

Lipstick Chromatography/Ink Chromatography

For Teachers 4th - 7th
Junior crime scene investigators are instructed in two different chromatography exercises. For female suspects, they separate and compare lipstick pigments. For male suspects, they separate and compare ink samples. A data sheet is...
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PPT
Curated OER

Chromatography

For Teachers 11th - 12th
Advanced techniques for the lab use of chromatography are detailed here and your students will learn the specifics of separating molecules using a staionary and mobile medium. Diagrams of the equipment used and some facts about how...
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Lesson Plan
Curated OER

Recognition and Classification of Mixtures

For Teachers 9th - 12th
Immerse your chemistry class in solutions! They melt and compare the mixtures that make up margarine, separate black ink into its component colors, distill ocean saltwater, and practice chromatography with plant pigments. There are eight...
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Lesson Plan
Curated OER

Chromatography

For Teachers 9th - 12th
High schoolers use chromatography to separate substances in Kool-Aid, Crayola markers and leaves. In this chromatography lesson plan, students make chromatograms to separate substances in a mixture through absorption. High schoolers find...
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Lesson Plan
Royal Society of Chemistry

Aspirin—The Wonder of Medicine

For Teachers 9th - Higher Ed Standards
What do aspirin and the willow tree have in common? Scholars of chemical synthesis engage in a fascinating reaction to make their own aspirin samples. The lab uses thin layer chromatography analysis, includes stoichiometric calculations,...
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Worksheet
Curated OER

Relationships and Biodiversity Lab

For Students 9th - 12th
In this relationships and biodiversity worksheet, students investigate the relationships between 4 plants sample using 7 different tests. These include looking at structural characteristics of the plants, seeds and stems, using paper...
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Lesson Plan
Curated OER

Standard One: Lab Design and Appendix A Lab Skills

For Teachers 9th - 12th
In this lab design and lab skills worksheet, students answer questions about experimental design including finding variables, determining controls, and graphing data. They answer questions about microscopy and label the parts of a...
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Lesson Plan
Curated OER

Straw Chromatography

For Teachers 9th - 12th
Students become acquainted with the principles of liquid chromatography and construct a liquid chromatography column. Students also investigate the effects of different solvents and solvent concentrations in the separation process.
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Lesson Plan
Curated OER

Using Thin Layer Chromatography To Identify amino Acids In Solution

For Teachers 8th - 11th
Students will work in groups to design and conduct an experiment to identify amino acids found in an unknown solution. This lesson is taught in three sections: (1) Introduction to chromatography (2) Experimental design session (3)...
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Lesson Plan
Curated OER

Paper Chromatography K-12 Experiment

For Teachers 8th - 12th
Students study chromatography and how they can distinguish between the different pigments in a color.  In this chromatography instructional activity students separate a mixture of dyes in soluble ink then record the colors they see. 
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Lab Resource
Royal Society of Chemistry

Chemistry Masterclass—Chemistry Outreach

For Teachers 10th - Higher Ed Standards
Immerse your chemistry class in the world of organic chemistry! Science scholars isolate acetaminophen from an over-the-counter sample during an intense and interesting lab. Groups use many different separation and analysis techniques to...
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Lesson Plan
Curated OER

Using Plant Pigments to Link a Suspect to a Crime

For Teachers 9th - 12th
Students use chromatography to separate plant pigments collected from a fictitious crime scene and suspects. They compare the Rf values of the plant pigments to determine whether the plant pigments found on any of the suspects match the...
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Lesson Plan
Chymist

The Extraction and Identification of Artificial Food Colors

For Teachers 9th - 12th Standards
Did you know some food dyes are considered safe while others are considered carcinogenic? During the experiment, young chemists extract artificial food colors from prepared foods. Then, they use chromatography paper to identify which...
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Lesson Plan
Curated OER

Chromatography

For Teachers 8th - 12th
Students conduct various experiments on chromatography. In this chemistry lesson, students distinguish among the different types of chromatography methods. They explain how the stationary and mobile phase interact with each other.
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Lesson Plan
Curated OER

Thin Layer Chromatography (TLC)

For Teachers 6th - 8th
Students study flavinoids and how they exist in the plant kingdom.  In this pigment lesson students complete a lab activity to see how flavinoids move in substances then record their observations.
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Lesson Plan
Curated OER

Column Chromatography

For Teachers 10th - 12th
Students research the mechanics of liquid chromatography. In this technology instructional activity, students calculate the concentration of unknown samples. They write a report about their research and lab results.

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