Concord Consortium
3D Exploration of Bound Antibody and Antigen
Our body manufactures antibodies that are the exact shape for the antigens it encounters. The simulation shows a 3-D model of an antibody and antigen pairing. It allows young scientists to explore the complementary shapes.
Exploratorium
Antibody Attack - Discover How Antibodies Launch Attacks on Invaders
Jump into the action and help antibodies defend against an antigen attack! Investigators match antibodies with antigens to model the body's identification and recall of specific pathogens. Young biologists also recognize that each...
Curated OER
Antibodies
Students conduct a series of exploration activity on how vaccines and antibodies work. In this biology lesson, students test how antigens and antibodies work in the body. They discuss the benefits of vaccines in promoting immune responses.
Curated OER
Antigens versus Antibodies "KO'd in Round Three" The Third Line of Defense of the Human Immune System
Seventh graders investigate antibodies, as the body's third line of defense against disease. They discover why antibodies do not defend the body against viruses and create a pantomime of the antibody/antigen/HIV relationship.
Curated OER
Were the babies switched? – The Genetics of Blood Types
Human biology or genetics learners apply their knowledge to a unique situation: two newborn baby girls being possibly switched in the hospital. The engaging activity ends with a Punnett squares assignment in which pupils evaluate whether...
Curated OER
Antigens
Students examine antigens including ones found in humans. For this immune lesson students complete several experiments in relation to antigens and antibodies.
Curated OER
Antibody Center Template
In this antibodies instructional activity, learners use model diagrams of antigens, antibodies and blood cells to develop a visual understanding of the immune system. They draw diagrams of antibodies and antigens attached to each other...
Curated OER
Antibodies and Antigens: Fitting Together
Using basic matching, aspiring biologists connect types of antigens with the antibodies that fight them. Provide ample instruction prior to assigning this one-sheet resource. Require students to explain in writing how each antibody works...
Curated OER
Teaching Multiple Alleles
Students view a simple ABO blood system for the introduction of this subject using concrete models of eythrocytes (red blood cells, or RBC's), antigens, and antibodies. They can physically see the antigens that result from certain...
Curated OER
Blood
In this blood activity, high schoolers complete a crossword puzzle given 24 clues about the components of the blood, the cells of the blood and the immune system with its antigens and antibodies found in the blood.
Curated OER
Multiple Alleles
Young scholars observe models of the ABO blood system including erythrocytes, antigens, and antibodies. They investigate the antigens that result from certain allele combinations and move antibodies to determine whether agglutination ...
Curated OER
Molecular Recognition and the Immune Response
Young scholars explore the importance of molecular shape and charge in molecular-recognition. They examine the interaction between antigens and antibodies. Students design and build 3-D visual models to represent molecular-recognition...
Curated OER
A Pox No Longer Upon Us
Tenth graders research the development and use of vaccines. They examine historical documents for qualitative observations and the basis of immunization. They examine primary and secondary immune responses as they relate to the...
Curated OER
The Genetics of Antibody Diversity
Students distinguish between the light and heavy chain sections. For this biology lesson, students simulate the DNA splicing process. They calculate antibody diversity using the information given.
Curated OER
Antibody and Antibody Specificity The Egg Mishap
Pupils investigate a set of foods to find the presence of eggs after designing an experiment that will complete the test. They complete a test and discuss antibody-antigen specificity.
Children’s Hospital of Philadelphia
Development of Disease and Infection
It's all in the cards. Using cards to simulate a disease's attack on the immune system, pupils develop an understanding of how the immune system and pathogens react to each other and why at times the pathogen wins. Groups play a game to...
Curated OER
Disease Diagnosis
Learners comprehend how biotechnology can be used to diagnose infectious disease such as protein technologies vs. DNA technologies. They comprehend procedure and uses of PCR, Western Blot, and ELISA as diagnostic tools. Students know how...
Curated OER
The Immune System
Activate the immune system in the brains of your biologists! This learning exercise calls upon learners to explain the structure, function, and problems associated with the immune system. This learning exercise is helpful for the...
Curated OER
Your Immune System
In this immune system activity, students describe an antibody and how it functions. Then they determine sources of passive immunity and how HIV affects the immune system. Students also name defenses that the digestive system has against...
Curated OER
ABO Blood Types Worksheet
Blood types and transfusions are explained in reading passages at the top of the instructional activity. A chart of blood type compatibility is also provided. Biology students answer comprehension questions and then exercise...
Curated OER
Operation Anitbody
Students identify the types of cells that are important in the immune system. They investigate the different mechanisms used by white blood cells as they protect the body from foreign invaders. Students are given five case studies,...
Curated OER
Common Vaccinations
Middle schoolers examine vaccinations and how they work. In this vaccinations lesson students create posters that describe the various types of vaccines.
Curated OER
Body Battles!
Seventh graders explain the role of white blood cells in fighting infections. In this life science lesson, 7th graders create flow charts showing the immune response process. They act out and play a game to simulate actions of the immune...
Curated OER
Food Forensics: A Case of Mistaken Identity
Ninth graders explore the specific reaction between an antigen and the antibody that recognizes it. They carry out an exploratory experiment leading to the concept of specificity.