Concord Consortium
3D Exploration of Bound Antibody and Antigen
Our body manufactures antibodies that are the exact shape for the antigens it encounters. The simulation shows a 3-D model of an antibody and antigen pairing. It allows young scientists to explore the complementary shapes.
Curated OER
Antibodies and Antigens: Fitting Together
Using basic matching, aspiring biologists connect types of antigens with the antibodies that fight them. Provide ample instruction prior to assigning this one-sheet resource. Require students to explain in writing how each antibody works...
Curated OER
Antigens
Students examine antigens including ones found in humans. For this immune lesson students complete several experiments in relation to antigens and antibodies.
Curated OER
Were the babies switched? – The Genetics of Blood Types
Human biology or genetics learners apply their knowledge to a unique situation: two newborn baby girls being possibly switched in the hospital. The engaging activity ends with a Punnett squares assignment in which pupils evaluate whether...
Curated OER
Antibody Center Template
In this antibodies instructional activity, learners use model diagrams of antigens, antibodies and blood cells to develop a visual understanding of the immune system. They draw diagrams of antibodies and antigens attached to each other...
Curated OER
Teaching Multiple Alleles
Students view a simple ABO blood system for the introduction of this subject using concrete models of eythrocytes (red blood cells, or RBC's), antigens, and antibodies. They can physically see the antigens that result from certain...
Curated OER
Antigens versus Antibodies "KO'd in Round Three" The Third Line of Defense of the Human Immune System
Seventh graders investigate antibodies, as the body's third line of defense against disease. They discover why antibodies do not defend the body against viruses and create a pantomime of the antibody/antigen/HIV relationship.
Exploratorium
Antibody Attack - Discover How Antibodies Launch Attacks on Invaders
Jump into the action and help antibodies defend against an antigen attack! Investigators match antibodies with antigens to model the body's identification and recall of specific pathogens. Young biologists also recognize that each...
Curated OER
Disease Diagnosis
Students comprehend how biotechnology can be used to diagnose infectious disease such as protein technologies vs. DNA technologies. They comprehend procedure and uses of PCR, Western Blot, and ELISA as diagnostic tools. Students know how...
Curated OER
The Immune System
Activate the immune system in the brains of your biologists! This learning exercise calls upon learners to explain the structure, function, and problems associated with the immune system. This learning exercise is helpful for the...
Baylor College
Defending Against Microbes
In the preceding lesson from the unit, beginning biologists discovered that microorganisms are everywhere, so the question follows, why are we not sick all of the time? Class members read and discuss an article in small groups about...
Curated OER
Molecular Recognition and the Immune Response
Young scholars explore the importance of molecular shape and charge in molecular-recognition. They examine the interaction between antigens and antibodies. Students design and build 3-D visual models to represent molecular-recognition...
Curated OER
Blood Type
In this blood type worksheet, students create a wheel showing blood type, antigens and the genes involved in coding for each blood type. Students use the wheel to answer 16 questions about blood type and they complete a chart with the...
Curated OER
Antibodies
Students conduct a series of exploration activity on how vaccines and antibodies work. In this biology lesson, students test how antigens and antibodies work in the body. They discuss the benefits of vaccines in promoting immune responses.
Curated OER
Using Blood-Typing to Determine Causes of Death in Surgery Patients
In this simulation activity, young biologists examine blood types to determine whether the death rate in a hospital was caused because of incorrect identification of patient blood types. You will need obtain and follow the procedures of...
Curated OER
Operation Anitbody
Students identify the types of cells that are important in the immune system. They investigate the different mechanisms used by white blood cells as they protect the body from foreign invaders. Students are given five case studies,...
Curated OER
Food Forensics: A Case of Mistaken Identity
Ninth graders explore the specific reaction between an antigen and the antibody that recognizes it. They carry out an exploratory experiment leading to the concept of specificity.
Curated OER
Body Battles!
Seventh graders explain the role of white blood cells in fighting infections. In this life science lesson, 7th graders create flow charts showing the immune response process. They act out and play a game to simulate actions of the immune...
Curated OER
Pre-Hardy-Weinberg
Pupils examine the inheritance of ABO blood groups. In this investigative lesson students perform a lab and show how natural selection can alter the gene frequencies in a population.
Curated OER
Your Immune System
In this immune system activity, students describe an antibody and how it functions. Then they determine sources of passive immunity and how HIV affects the immune system. Students also name defenses that the digestive system has against...
Curated OER
Antigen Switching in Malaria
Students model how the malaria-causing protist avoids immune response in its host. In this parasite biology lesson, students use printed cell images to model the way that Plasmodium changes surface protein markers every few generations...
Curated OER
Using Blood Tests to Identify Babies and Criminals
Students solve a crime by matching a suspect's blood type to physical evidence collected at the crime scene. In this forensic science instructional activity, students identify the different blood types. They explain how blood tests work.
National WWII Museum
A New War Weapon to Save Lives
Young historians view and analyze photos and documents from WWII that are related to blood transfusions and blood plasma. A demonstration of correct and incorrect blood donors visually shows the importance of knowing blood type. After...
Curated OER
Student Investigation on the Immune System and Hemeagglutination
Students perform an experiment to demonstrate the principles of antibody-antigen binding, the secondary immune response, cross reactivity, and complement fixation. The materials to be used include antibodies from a rabbit that was...
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