{"page":"\u003clink rel=\"stylesheet\" href=\"https://lessonplanet.com/assets/packs/css/resources-c03aa079.css\" /\u003e\n\u003clink rel=\"stylesheet\" href=\"https://lessonplanet.com/assets/packs/css/lp_boclips_stylesheets-517835be.css\" media=\"all\" /\u003e\n\u003cdiv data-title='How COVID-19 Works and Why It Became So Dangerous' data-url='/boclips/videos/689566e68b3f8d9d4df8e335' data-video-url='/boclips/videos/689566e68b3f8d9d4df8e335' id='bo_player_modal'\u003e\n\u003cdiv class='boclips-resource-page modal-dialog panel-container'\u003e\n\u003cdiv class='react-notifications-root'\u003e\u003c/div\u003e\n\u003cdiv class='rp-header'\u003e\n\u003cdiv class='rp-type'\u003e\n\u003ci aria-hidden='true' class='fai fa-regular fa-circle-play'\u003e\u003c/i\u003e\nVideo\n\u003c/div\u003e\n\u003ch1 class='rp-title' id='video-title'\u003e\nHow COVID-19 Works and Why It Became So Dangerous\n\u003c/h1\u003e\n\u003cdiv class='rp-actions'\u003e\n\u003cdiv class='mr-1'\u003e\n\u003ca class=\"btn btn-success\" data-posthog-event=\"Signup: LP Signup Activity\" data-posthog-location=\"body_link_boclips\" data-remote=\"true\" href=\"/subscription/new\"\u003e\u003cspan\u003e\u003cspan\u003eGet Free Access\u003c/span\u003e\u003cspan class=\"\"\u003e for 10 Days\u003c/span\u003e\u003cspan\u003e!\u003c/span\u003e\u003c/span\u003e\u003c/a\u003e\n\u003c/div\u003e\n\u003c/div\u003e\n\u003c/div\u003e\n\u003cdiv class='rp-body'\u003e\n\u003cdiv class='rp-info'\u003e\n\u003cdiv aria-label='Hide resource details' class='rp-hide-info' role='button' tabindex='0'\u003e\u0026times;\u003c/div\u003e\n\u003ci aria-label='Expand resource details' class='rp-expand-info fai fa-solid fa-up-right-and-down-left-from-center' role='button' tabindex='0'\u003e\u003c/i\u003e\n\u003ci aria-label='Compress resource details' class='rp-compress-info fai fa-solid fa-down-left-and-up-right-to-center' role='button' tabindex='0'\u003e\u003c/i\u003e\n\u003cdiv class='rp-rating'\u003e\n\u003cspan class='resource-pool'\u003e\n\u003cspan class='pool-label'\u003ePublisher:\u003c/span\u003e\n\u003cspan class='pool-name'\u003e\n\u003cspan class='text'\u003e\u003ca data-publisher-id=\"30356011\" href=\"/search?publisher_ids%5B%5D=30356011\"\u003eCurated Video\u003c/a\u003e\u003c/span\u003e\n\u003c/span\u003e\n\u003c/span\u003e\n\u003c/div\u003e\n\u003cdiv class='rp-description'\u003e\n\u003cspan class='short-description'\u003eHow does coronavirus work? What makes the coronavirus so good at what it does? Why is Covid so deadly? How to protect yourself from SARS-CoV-2.The growth of infections, and the percentage of infected people that need hospitalizations is...\u003c/span\u003e\n\u003cspan class='full-description hide'\u003eHow does coronavirus work? What makes the coronavirus so good at what it does? Why is Covid so deadly? How to protect yourself from SARS-CoV-2.The growth of infections, and the percentage of infected people that need hospitalizations is too high. What makes this virus so different from the cold or the flu? \u003cbr/\u003e\u003cbr/\u003eIt's because this is a mutant hybrid. They are tiny. 100 million would fit on the head of a pin.  Each coronavirus particle consists of a small set of genes, enclosed by a coating of protein, and in this case, it's enclosed in a sphere of fatty lipid molecules. Since they contain genes - RNA , so they can evolve via mutations and natural selection. RNA is less stable than DNA, so they tend to change and evolve faster than DNA viruses. \u003cbr/\u003e\u003cbr/\u003eThe evolutionary goal of a virus is to make as many copies of itself as it can. The outer structure of the virus a spiky ball, which recognizes and stick to a protein ACE2, on the surface of some of cells, such as lung and kidney cells. The shape of the spikes allow it to stick more strongly to ACE2, than the classic SARS, and that makes it be more infectious because fewer viruses are needed for transmission.   \u003cbr/\u003e\u003cbr/\u003eACE2 is produced in greater quantities in people with diabetes, so this is a reason that such people are more susceptible to severe COVID-19. \u003cbr/\u003e\u003cbr/\u003eOnce a virus sticks to a cell, it allows RNA to enter the cell. Then it hijacks the cell’s protein synthesis in Ribosomes. The cell starts making copies of the virus. When most RNA viruses replicate, it leads to many mutations.  Most mutations are bad, and kill the virus. But SARS-CoV-2 virus, has a spell-check mechanism so it can correct errors during the replications process, becoming harder to kill. Once copies are made, they disperse to invade more cells. This triggers an intense immune response from your body. But this reaction swells your tissues in the lungs making it harder to breathe. \u003cbr/\u003e\u003cbr/\u003eMost viruses infect either the upper respiratory tract - the nose, mouth and throat, like the common cold, which makes it very contagious, but mild; Or they infect the lower respiratory tract - your bronchial tubes and lungs, like SARS classic and MERS, where they are less contagious but deadlier. But SARS-CoV-2 infects both the upper and lower respiratory tracts. This makes it not only be more severe, but also highly contagious.  \u003cbr/\u003e\u003cbr/\u003eIt could also explain why it transmits so easily because it starts off as an upper respiratory infection when people may feel few symptoms, abd thus could be unwittingly spread the virus. It’s only 5-14 days later, that the virus progresses to the lower respiratory tract when people start getting severe symptoms.\u003cbr/\u003e\u003cbr/\u003eAnother reason for its higher rates of spread vs. MERS is that when people get the latter, they were more quickly debilitated, so they could not spread the disease. But with coronavirus, people don't even know that they have it.\u003cbr/\u003e\u003cbr/\u003eThey reason coronavirus starts out in your nose, throat or lungs is because they are exposed to the air. Covid19 is not like the flu. Fatality rate is 2.8% vs. 0.13% for flu. Even if 50% of infected people show no symptoms, this is still 10 times more deadly than the flu. Researchers estimate that COVID-19 is about twice more infectious than flu – one person on average affects 3 people, whereas someone with the flu infects 1.6 people. Hospitalization rates for people with COVID-19 is high - 20 percent, compared to 1.4% for flu victims.\u003cbr/\u003e\u003cbr/\u003eThe closest relative of SARS-CoV-2 is found in bats, which suggests it originated in a bat, then jumped to humans either directly or through another species like the pangolin. This crossover usually requires multiple genetic mutations. But SARS-CoV-2 appears to not have mutated.   \u003cbr/\u003e\u003cbr/\u003eIs this virus man-made? “What are the odds that a random bat virus had exactly the right combination of traits to be the perfect virus to bring down human civilization?”  Remember that there are trillions of viruses undergoing billions of mutations all the time.  And odds are high that in course of human history, such a virus emerges. Also coronavirus has been analyzed by multiple scientists, and it was found to be naturally occurring. \u003cbr/\u003e\u003cbr/\u003eHow do you protect yourself? Antibiotics will not work because they only kill bacteria. But good news, the virus is very fragile. It is only protected by a thin layer of fat. This is why soap and water is the best method to kill it. Soaps and detergents cut the fat. 65% or higher alcohol \u0026 Chlorine will also kill the virus but vinegar will not. Heat melts fats, so cook your food.\u003cbr/\u003e\u003cbr/\u003eCoronavirus survives for a day on cardboard, three days on metals and plastics. Also dusting could release the virus in the air allowing it to get into you. \u003cbr/\u003e\u003cbr/\u003eWhat about wearing a mask? Only the only N95 mask will work. If you have a mask then wear it. Don’t buy a mask because then you might be taking it away from a health care worker. But this advice is my opinion. Stay home if possible.\u003c/span\u003e\n\u003c/div\u003e\n\u003cdiv class='action-container flex justify-between'\u003e\n\u003cbutton aria-expanded='false' aria-label='Read more description' class='rp-full-description' type='button'\u003e\n\u003ci class='fai fa-solid fa-align-left'\u003e\u003c/i\u003e\n\u003cspan id='read_more'\u003eRead More\u003c/span\u003e\n\u003c/button\u003e\n\u003cdiv class='rp-report'\u003e\n\u003c/div\u003e\n\u003c/div\u003e\n\u003cdiv aria-labelledby='resource-details-heading' class='rp-info-section'\u003e\n\u003ch2 class='title' id='resource-details-heading'\u003eResource Details\u003c/h2\u003e\n\u003cdiv class='rp-resource-details clearfix'\u003e\n\u003cdiv class='detail'\u003e\n\u003cdl\u003e\n\u003cdt\u003eCurator Rating\u003c/dt\u003e\n\u003cdd\u003e\u003cspan class=\"star-rating\" aria-label=\"4.0 out of 5 stars\" role=\"img\"\u003e\u003ci class=\"fa-solid fa-star text-action\" aria-hidden=\"true\"\u003e\u003c/i\u003e\u003ci class=\"fa-solid fa-star text-action\" aria-hidden=\"true\"\u003e\u003c/i\u003e\u003ci class=\"fa-solid fa-star text-action\" aria-hidden=\"true\"\u003e\u003c/i\u003e\u003ci class=\"fa-solid fa-star text-action\" aria-hidden=\"true\"\u003e\u003c/i\u003e\u003ci class=\"fa-regular fa-star text-action\" aria-hidden=\"true\"\u003e\u003c/i\u003e\u003c/span\u003e\u003c/dd\u003e\n\u003c/dl\u003e\n\u003c/div\u003e\n\u003cdiv class='detail'\u003e\n\u003cdl\u003e\n\u003cdt class=\"educator-rating-title\"\u003eEducator Rating\u003c/dt\u003e\u003cdd\u003e\u003cdiv class=\"educator-rating-details\" data-path=\"/educator_ratings/rrp_data?resourceable_id=91139922\u0026amp;resourceable_type=Boclips%3A%3AVideoMetadata\"\u003e\u003cspan class=\"not-yet-rated\"\u003eNot yet Rated\u003c/span\u003e\u003c/div\u003e\u003c/dd\u003e\n\u003c/dl\u003e\n\u003c/div\u003e\n\u003cdiv class='detail'\u003e\n\u003cdl\u003e\n\u003cdt\u003eMedia Length\u003c/dt\u003e\n\u003cdd\u003e13:11\u003c/dd\u003e\n\u003c/dl\u003e\n\u003c/div\u003e\n\u003cdiv class='detail'\u003e\n\u003cdl\u003e\n\u003cdt\u003eGrade\u003c/dt\u003e\u003cdd title=\"Grade\"\u003e12th - Higher Ed\u003c/dd\u003e\n\u003c/dl\u003e\n\u003c/div\u003e\n\u003cdiv class='detail'\u003e\n\u003cdl\u003e\n\u003cdt\u003eSubjects\u003c/dt\u003e\u003cdd\u003e\u003cspan\u003e\u003ca href=\"/search?grade_ids%5B%5D=259\u0026amp;grade_ids%5B%5D=258\u0026amp;search_tab_id=1\u0026amp;subject_ids%5B%5D=1319782\"\u003eCareer \u0026amp; 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href=\u0026quot;/auth/users/sign_in\u0026quot;\u003eSign in\u003c/a\u003e or \u003ca class=\u0026quot;bold text-danger\u0026quot; data-posthog-event=\u0026quot;Signup: LP Signup Activity\u0026quot; data-posthog-location=\u0026quot;body_link_boclips\u0026quot; data-remote=\u0026quot;true\u0026quot; href=\u0026quot;/subscription/new\u0026quot;\u003eJoin Now\u003c/a\u003e\u003c/div\u003e\" data-title=\"Get Full Access\" data-container=\"body\" rel=\"popover\" tabindex=\"0\" aria-label=\"Play video: How COVID-19 Works and Why It Became So Dangerous\" href=\"/subscription/new\"\u003e\u003cimg class=\"resource-img img-thumbnail img-responsive z-10 lp-boclips-thumbnail w-full h-full lozad\" alt=\"How COVID-19 Works and Why It Became So Dangerous\" title=\"How COVID-19 Works and Why It Became So Dangerous\" onError=\"handleImageNotLoadedError(this)\" data-default-image=\"https://static.lp.lexp.cloud/images/attachment_defaults/resource/large/missing.png\" data-src=\"https://cdnapisec.kaltura.com/p/1776261/thumbnail/entry_id/1_r6tzhk98/width/250\" width=\"315\" height=\"220\" src=\"data:image/png;base64,R0lGODlhAQABAAD/ACwAAAAAAQABAAACADs\" /\u003e\n\u003cspan aria-hidden='true' class='flex justify-center items-center bg-white rounded-full w-16 h-16 absolute top-1/2 left-1/2 -mt-8 -ml-8 cursor-pointer z-0 border-2 border-primary drop-shadow-md lp-boclips-thumbnail-playBtn'\u003e\n\u003ci class='fa-solid fa-play text-primary text-3xl ml-1 drop-shadow-xl'\u003e\u003c/i\u003e\n\u003c/span\u003e\n\u003c/a\u003e\u003c/div\u003e\n\u003c/div\u003e\n\u003c/div\u003e\n\u003c/div\u003e\n\u003c/div\u003e\n\u003c/div\u003e\n"}