{"page":"\n\n
\n
\n
\n
\n
\n\nVideo\n
\n

\nRepair of DNA Damage by Alkylating Agents\n

\n
\n
\nGet Free Access for 10 Days!\n
\n
\n
\n
\n
\n
×
\n\n\n
\n\nPublisher:\n\nCurated Video\n\n\n
\n
\nIn some cases, a cell can fix DNA damage simply by reversing the chemical reaction that caused it. To understand this, we need to realize that \"DNA damage\" often just involves an extra group of atoms getting attached to DNA through a...\nIn some cases, a cell can fix DNA damage simply by reversing the chemical reaction that caused it. To understand this, we need to realize that \"DNA damage\" often just involves an extra group of atoms getting attached to DNA through a chemical reaction. For example, guanine (G) can undergo a reaction that attaches a methyl (-CH3) group to an oxygen atom in the base. The methyl-bearing guanine, if not fixed, will pair with thymine (T) rather than cytosine (C) during DNA replication. Luckily, humans and many other organisms have an enzyme that can remove the methyl group, reversing the reaction and returning the base to normal.\n
\n
\n\n
\n
\n
\n
\n

Resource Details

\n
\n
\n
\n
Curator Rating
\n
\n
\n
\n
\n
\n
Educator Rating
Not yet Rated
\n
\n
\n
\n
\n
Media Length
\n
1:51
\n
\n
\n
\n
\n
Grade
9th - Higher Ed
\n
\n
\n
\n
\n
Subjects
Science
6 more...
\n
\n
\n
\n
\n
Media Type
Instructional Videos
\n
\n
\n
\n
\n
Source:
\n
\nBioMagica\n\n
\n
\n
\n
\n
\n
Date
\n
2018
\n
\n
\n
\n
\n\n
Language
English
\n
\n
\n
\n
\n
Audiences
For Teacher Use
2 more...
\n
\n
\n
\n
\n
Usage Permissions
Fine Print: Educational Use
\n
\n
\n
\n
\n
\n

Additional Materials

\n
\n\nSign in or Join Now
\" data-title=\"Get Full Access\" data-container=\"body\" rel=\"popover\" tabindex=\"0\" href=\"/subscription/new\">Video Transcript\n
\n
\n\nSign in or Join Now
\" data-title=\"Get Full Access\" data-container=\"body\" rel=\"popover\" tabindex=\"0\" href=\"/subscription/new\">Video Preview\n
\n
\n
\n

Concepts

\n
\n
guanine, cytosine, thymine
\n
\n\n\n
\n
\n
\n
\n

Additional Tags

\n
\n
repair of dna damage by alkylating agents, dna repair, alkylating agents, 06 methyl guanine, o6 methyl guanine methyl transferase, csir ugc net, set, gate, methyl group, methyl, damage, repaired, ethyl, lead, pair, enzyme, 6 methylguanin
\n
\n\n\n
\n
\n
\n
\n

Classroom Considerations

\n
Video is ad-free
\n
\n
\n

Educator Ratings

\n
\n
\n
\n
\n
\n\nShow resource details\n
\n
\n\" data-title=\"Get Full Access\" data-container=\"body\" rel=\"popover\" tabindex=\"0\" aria-label=\"Play video: Repair of DNA Damage by Alkylating Agents\" href=\"/subscription/new\">\"Repair\n\n
\n
\n
\n\n\n\n"}