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\nGalactose Absorption and Metabolism | Leloir Pathway and Galactosemia\n

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\n\nPublisher:\n\nJJ Medicine\n\n\n
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\nLesson on galactose absorption, metabolism via the Leloir pathway, and the medical condition known as galactosemia. Galactose is monosaccharide, which is typically ingested in the form of lactose (galactose + glucose) or free galactose...\nLesson on galactose absorption, metabolism via the Leloir pathway, and the medical condition known as galactosemia. Galactose is monosaccharide, which is typically ingested in the form of lactose (galactose + glucose) or free galactose in certain fruits and vegetables. Upon ingestion and digestion, the galactose is transported into an intestinal endothelial cell through SGLT1 and transported into the blood via GLUT2. Upon entry into a receiving cell, galactose is metabolized by the Leloir pathway to form glucose-6-phosphate, which can be rerouted and utilized in the glycolysis pathway to form ATP and pyruvate. If there are any congenital issues causing deficiency in one of three enzymes in the Leloir pathway, this can lead to dysfunctional galactose metabolism and subsequent high blood levels of galactose, leading to issues with red blood cell functioning and increasing risk of cataract formation.\n
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Resource Details

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Educator Rating
Not yet Rated
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Media Length
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6:44
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Grade
Higher Ed
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Subjects
Science
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Media Type
Instructional Videos
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Source:
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\nJJ Medicine\n\n
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Date
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2017
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Language
English
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Audiences
For Teacher Use
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Fine Print: Educational Use
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Concepts

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glucose, leads
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Additional Tags

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galactose metabolism, galactose absorption, galactose metabolism pathway, galactose digestion, leloir pathway, galactose and leloir pathway, galactosemia, galactose to glucose, galactose metabolism animation, galactose breakdown, galactose structure, galactose metabolism biochemistry, leloir metabolic pathway, galactosemia pathway, galactosemia animation, galactosemia usmle, galactose metabolism usmle, galactose metabolism steps, absorption of glucose and galactose, dietary sources, intestinal lumen, phosphate group, udp glucose, form pyruvate, lactose synthesis, free galactose, udp galactose, form, lactose, galactose, ingested, fructose, enzyme, alpha, deficiency, beta, metabolized, transported, glued 2, bloodstream, rearranged, processed, cell, converted, utilized
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