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\nHereditary Spherocytosis | Pathophysiology, Symptoms, Diagnosis and Treatment\n

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\n\nPublisher:\n\nJJ Medicine\n\n\n
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\nLesson on Hereditary Spherocytosis (Minkowski-Chauffard Syndrome): Introduction, Pathophysiology, Signs and Symptoms, Diagnosis and Treatment. Hereditary spherocytosis is an inherited hemolytic anemia, more common in Northern European...\nLesson on Hereditary Spherocytosis (Minkowski-Chauffard Syndrome): Introduction, Pathophysiology, Signs and Symptoms, Diagnosis and Treatment. Hereditary spherocytosis is an inherited hemolytic anemia, more common in Northern European populations, that is due to a mutation in a red blood cell membrane protein, such as Ankyrin. The mutation in membrane protein ankyrin leads to formation of spherocytes, red blood cells that lack central pallor, are smaller than typical red blood cells and have decreased surface area and decreased ability to deform. The decreased ability to deform leads to early removal and destruction of the red blood cells in the spleen of these patients, leading to increases in spleen size (splenomegaly), anemia, reticulocytosis and other symptoms.

Hey everyone! This is a lesson the blood disorder known as hereditary spherocytosis (aka Minkowski-Chauffard syndrome). In this lesson you will learn about the epidemiology of hereditary spherocytosis, the pathophysiology and function of ankyrin protein, signs and symptoms of this disease, tests to help diagnose the disease and treatments.\n
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Resource Details

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Educator Rating
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Media Length
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12:37
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Grade
Higher Ed
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Subjects
Science
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Media Type
Instructional Videos
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Source:
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\nJJ Medicine\n\n
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Date
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2018
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Language
English
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Audiences
For Teacher Use
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Fine Print: Educational Use
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Concepts

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anemia, symptoms
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hereditary spherocytosis, minkowski chauffard syndrome, hereditary spherocytosis symptoms, hereditary spherocytosis diagnosis, hereditary spherocytosis treatment, pathophysiology of hereditary spherocytosis, ankyrin and hereditary spherocytosis, clinical presentation of hereditary spherocytosis, hereditary spherocytosis usmle, hereditary spherocytosis pathology, hereditary spherocytosis animation, hereditary spherocytosis osmosis, hereditary spherocytosis khan academy, sphere sites, aplastic crisis, high reticulocytosis, predatory spherocytosis, increased amount, increased mchc, early removal, severe cases, hereditary, splenomegaly, severe, mutations, body, typically, present, severity, cases, individuals, spherocytes, increases, spectrum, hemolysis, spleen, patients, rest, cell, mentioned
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\n\" data-title=\"Get Full Access\" data-container=\"body\" rel=\"popover\" tabindex=\"0\" aria-label=\"Play video: Hereditary Spherocytosis | Pathophysiology, Symptoms, Diagnosis and Treatment\" href=\"/subscription/new\">\"Hereditary\n\n
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