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\nHeme Catabolism and Degradation Pathway - Biochemistry Lesson\n

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\n\nPublisher:\n\nJJ Medicine\n\n\n
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\nVideo lesson on catabolism and degradation of heme from hemoglobin during red blood cell (erythrocyte) hemolysis in a powerpoint, university-styled lecture! Hey guys! In this video I (attempt to) simplify and explain the heme catabolism...\nVideo lesson on catabolism and degradation of heme from hemoglobin during red blood cell (erythrocyte) hemolysis in a powerpoint, university-styled lecture!

Hey guys! In this video I (attempt to) simplify and explain the heme catabolism pathway in a (hopefully easy) step-by-step lesson! I first start by explaining basics of the physiology and function of a red blood cell (aka erythrocyte) and that hemoglobin is released from red blood cells during degradation or hemolysis. I next explain hemoglobin is taken up by the reticuloendothelial system (white blood cells like macrophages) and converted to heme. Heme is then converted to biliverdin and then bilirubin, and the iron moiety of heme is stored in ferritin and hemosiderin in white blood cells. From here I explain step-by-step bilirubin metabolism in liver hepatocytes, conjugation and incorporation into bile in the gallbladder, conversion to urobilinogen and stercobilin and urobilin in the urine.

I also discuss the enzymes required for each step of the heme catabolism pathway.

At the end of the video, I also provide quick facts regarding erythrocytes, hemoglobin, and bilirubin and the clinical \"standard\" lab values of blood serum bilirubin.\n
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Resource Details

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Educator Rating
Not yet Rated
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Media Length
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10:53
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Grade
Higher Ed
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Subjects
Science
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Media Type
Instructional Videos
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Source:
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\nJJ Medicine\n\n
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Date
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2017
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Language
English
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Audiences
For Teacher Use
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Usage Permissions
Fine Print: Educational Use
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Concepts

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hemoglobin, iron, blood, time, oxygen, catabolism
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Additional Tags

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heme, hemolysis, bilirubin, biliverdin, stercobilin, urobilin, erythrocyte, hematology, jjbartleyscience, heme metabolism, heme catabolism, degradation, heme degradation made easy, heme breakdown, heme catabolism simplified, bilirubin metabolism made easy, heme metabolism lesson, learn heme catabolism, medicine simplified, how does heme get metabolized, how does heme get broken down, catabolism of heme, heme catabolism pathway, heme catabolism bilirubin, reticuloendothelial system, heme group, small intestine, intestinal bacteria, greatly appreciated, pigmented chemical, abundant protein, bill rubin, conjugated bilirubin, bill, guys, conjugated, reaction, transported, converted, continually, nadph, urobilinogen, broken, body, degraded, composed
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Classroom Considerations

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Best For: Explaining a topic
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