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\nCori Cycle | Lactic Acid Metabolism | Purpose and Importance in Anaerobic Metabolism\n

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\n\nPublisher:\n\nJJ Medicine\n\n\n
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\nLesson on the Cori cycle, introducing the importance and purpose of the Cori cycle and discussing how the Cori cycle can recycle lactic acid, produced from anaerobic metabolism in skeletal muscle, in the liver to form glucose through...\nLesson on the Cori cycle, introducing the importance and purpose of the Cori cycle and discussing how the Cori cycle can recycle lactic acid, produced from anaerobic metabolism in skeletal muscle, in the liver to form glucose through gluconeogenesis. Intensive exercise and other hypoxic conditions induce anaerobic metabolism in muscle cells, which leads to the production of lactic acid from pyruvate via the enzyme lactate dehydrogenase (LDH). If this lactic acid is left in the muscle cell, the pH of the muscle cell can decrease and cause detrimental effects to the muscle. Therefore, the lactic acid is transported out of the muscle cell through specific transporters located in the muscle cell membrane. The hydrogen ions from the lactic acid are then buffered by the blood and/or removed from the blood in the form of carbon dioxide. The remaining lactate is transported into the liver, where it can be used as a precursor for gluconeogenesis.

Hey everyone! Here is a lesson on the Cori cycle and lactic acid metabolism. In this lesson, you will learn the differences between aerobic and anaerobic metabolism in skeletal muscle, and how lactic acid is produced. You will also learn how that lactic acid is transported out of the cell and into the blood, and how the blood buffers and removes excessive hydrogen ions (protons) produced from lactic acid hydrolysis. This video then discusses how the lactate is transported into the liver hepatocyte, and how the lactate is used as a precursor for gluconeogenesis.\n
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Resource Details

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Educator Rating
Not yet Rated
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Media Length
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10:59
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Grade
Higher Ed
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Subjects
Science
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Media Type
Instructional Videos
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Source:
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\nJJ Medicine\n\n
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Date
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2017
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Language
English
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Audiences
For Teacher Use
2 more...
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Usage Permissions
Fine Print: Educational Use
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Concepts

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skeletal muscle, energy, glucose, glycolysis, oxygen
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Additional Tags

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cori cycle, cori cycle and lactate, cori cycle and lactic acid, lactic acid metabolism, cori cycle and anaerobic metabolism, aerobic and anaerobic metabolism, anaerobic metabolism and lactic acid, cori cycle animation, cori cycle pathway, cori cycle simplified, cori cycle explained, lactic acid cycle, lactic acid fermentation, lactic acid in muscles, cori cycle video, cori cycle biochemistry, the cori cycle, the cori cycle explained, the cori cycle steps, quarry cycle, intensive exercise, lactic acidosis, generating atp, tca cycle, hydrogen ions, lactic acid, anaerobic metabolism, pyruvate stays, entire process, monocarboxylate transporter, form glucose, muscle cell, oxygen present, glycolysis pathway, pyruvate produced, muscle, reaction, produced, present, pathway, cell, important, back, pyruvate
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Best For: Explaining a topic
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