{"page":"<link rel=\"stylesheet\" href=\"https://lessonplanet.com/assets/packs/css/resources-572d6a42.css\" />\n<link rel=\"stylesheet\" href=\"https://lessonplanet.com/assets/packs/css/lp_boclips_stylesheets-f4d0de30.css\" media=\"all\" />\n<div data-title='How Enzymes Denature | Cells | Biology | FuseSchool' data-url='/boclips/videos/625f7660b09c1a0537ece5ee' data-video-url='/boclips/videos/625f7660b09c1a0537ece5ee' id='bo_player_modal'>\n<div class='boclips-resource-page modal-dialog panel-container'>\n<div class='react-notifications-root'></div>\n<div class='rp-header'>\n<div class='rp-type'>\n<i aria-hidden='true' class='fai fa-regular fa-circle-play'></i>\nVideo\n</div>\n<h1 class='rp-title' id='video-title'>\nHow Enzymes Denature | Cells | Biology | FuseSchool\n</h1>\n<div class='rp-actions'>\n<div class='mr-1'>\n<a class=\"btn btn-success\" data-posthog-event=\"Signup: LP Signup Activity\" data-posthog-location=\"body_link_boclips\" data-remote=\"true\" href=\"/subscription/new\"><span><span>Get Free Access</span><span class=\"\"> for 10 Days</span><span>!</span></span></a>\n</div>\n</div>\n</div>\n<div class='rp-body'>\n<div class='rp-info'>\n<div aria-label='Hide resource details' class='rp-hide-info' role='button' tabindex='0'>&times;</div>\n<i aria-label='Expand resource details' class='rp-expand-info fai fa-solid fa-up-right-and-down-left-from-center' role='button' tabindex='0'></i>\n<i aria-label='Compress resource details' class='rp-compress-info fai fa-solid fa-down-left-and-up-right-to-center' role='button' tabindex='0'></i>\n<div class='rp-rating'>\n<span class='resource-pool'>\n<span class='pool-label'>Publisher:</span>\n<span class='pool-name'>\n<span class='text'><a data-publisher-id=\"30356011\" href=\"/search?publisher_ids%5B%5D=30356011\">Curated Video</a></span>\n</span>\n</span>\n</div>\n<div class='rp-description'>\n<span class='short-description'>How Enzymes Denature | Cells | Biology | FuseSchool Enzymes have optimal conditions under which they operate. Temperature, pH, enzyme concentration and substrate concentration are some conditions that affect the rate of reaction. As...</span>\n<span class='full-description hide'>How Enzymes Denature | Cells | Biology | FuseSchool Enzymes have optimal conditions under which they operate. Temperature, pH, enzyme concentration and substrate concentration are some conditions that affect the rate of reaction. As enzymes are proteins, they have an optimum temperature in which they work. They also have a temperature above which they start to denature. This means the active site starts to change shape, so that they can no longer facilitate a reaction. When the active site changes shape, the substrate can no longer fit into the enzyme. This is known as denaturation. Enzymes also have an optimum pH. Enzymes that work in the stomach can function under strongly acidic conditions, whereas other enzymes would denature in these conditions. 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