{"page":"\u003clink rel=\"stylesheet\" href=\"https://lessonplanet.com/assets/packs/css/resources-572d6a42.css\" /\u003e\n\u003clink rel=\"stylesheet\" href=\"https://lessonplanet.com/assets/packs/css/lp_boclips_stylesheets-f4d0de30.css\" media=\"all\" /\u003e\n\u003cdiv data-title='The Immune System' data-url='/boclips/videos/60cb6b7455dff626bad57560' data-video-url='/boclips/videos/60cb6b7455dff626bad57560' id='bo_player_modal'\u003e\n\u003cdiv class='boclips-resource-page modal-dialog panel-container'\u003e\n\u003cdiv class='react-notifications-root'\u003e\u003c/div\u003e\n\u003cdiv class='rp-header'\u003e\n\u003cdiv class='rp-type'\u003e\n\u003ci aria-hidden='true' class='fai fa-regular fa-circle-play'\u003e\u003c/i\u003e\nVideo\n\u003c/div\u003e\n\u003ch1 class='rp-title' id='video-title'\u003e\nThe Immune System\n\u003c/h1\u003e\n\u003cdiv class='rp-actions'\u003e\n\u003cdiv class='mr-1'\u003e\n\u003ca class=\"btn btn-success\" data-posthog-event=\"Signup: LP Signup Activity\" data-posthog-location=\"body_link_boclips\" data-remote=\"true\" href=\"/subscription/new\"\u003e\u003cspan\u003e\u003cspan\u003eGet Free Access\u003c/span\u003e\u003cspan class=\"\"\u003e for 10 Days\u003c/span\u003e\u003cspan\u003e!\u003c/span\u003e\u003c/span\u003e\u003c/a\u003e\n\u003c/div\u003e\n\u003c/div\u003e\n\u003c/div\u003e\n\u003cdiv class='rp-body'\u003e\n\u003cdiv class='rp-info'\u003e\n\u003cdiv aria-label='Hide resource details' class='rp-hide-info' role='button' tabindex='0'\u003e\u0026times;\u003c/div\u003e\n\u003ci aria-label='Expand resource details' class='rp-expand-info fai fa-solid fa-up-right-and-down-left-from-center' role='button' tabindex='0'\u003e\u003c/i\u003e\n\u003ci aria-label='Compress resource details' class='rp-compress-info fai fa-solid fa-down-left-and-up-right-to-center' role='button' tabindex='0'\u003e\u003c/i\u003e\n\u003cdiv class='rp-rating'\u003e\n\u003cspan class='resource-pool'\u003e\n\u003cspan class='pool-label'\u003ePublisher:\u003c/span\u003e\n\u003cspan class='pool-name'\u003e\n\u003cspan class='text'\u003e\u003ca data-publisher-id=\"30356647\" href=\"/search?publisher_ids%5B%5D=30356647\"\u003eFuseSchool\u003c/a\u003e\u003c/span\u003e\n\u003c/span\u003e\n\u003c/span\u003e\n\u003c/div\u003e\n\u003cdiv class='rp-description'\u003e\n\u003cspan class='short-description'\u003eThe main role of the immune system is to prevent disease caused by infection. Infections can be caused by a wide variety of pathogens, including bacteria, fungi, parasites (such as malaria) and viruses (such as influenza and the common...\u003c/span\u003e\n\u003cspan class='full-description hide'\u003eThe main role of the immune system is to prevent disease caused by infection. Infections can be caused by a wide variety of pathogens, including bacteria, fungi, parasites (such as malaria) and viruses (such as influenza and the common cold). The immune system comprises of a network of cells and tissues that work together to prevent disease. All parts of the body that interact with the external environment (such as the lungs, digestive tract and skin) have to be prepared to protect the body. The skin acts as a barrier to prevent pathogens entering the body. If you cut your leg, your skin protective barrier is broken and so bacteria are now able to enter your cut. Luckily, our bodies have an army of immune cells waiting for external invaders. These immune cells are called macrophages. They are able to recognise the bacteria as a threat, based on molecules the bacteria express on their surfaces. Once the macrophages recognised the bacteria, they can destroy the bacteria by eating (engulfing) it. This is a process called phagocytosis. At the same time, the phagocytes produce molecules called cytokines and chemokines. These alert the rest of the immune system to the presence of an invader. Different immune cells called neutrophils are then recruited to your leg. Along with the macrophages, they help to destroy the bacteria. Both the macrophages and neutrophils are part of the innate immune system. They provide the first line of defence against invading pathogens. If the invaders cannot be controlled by the innate immune system, then more specialised immune cells called lymphocytes are recruited. Lymphocytes include T-cells and B-cells. They work together to produce molecules like antibodies, which help to clear the infection. T and B cells are part of the adaptive immune system. Once these cells are activated, they are able to remember an infection. So that the next time the bacteria enters the body, they are able to be destroyed more rapidly. The innate and adaptive immune systems work together to fight off infections, and prevent the development of disease. At Fuse School, teachers and animators come together to make fun \u0026 easy-to-understand videos in Chemistry, Biology, Physics, Maths \u0026 ICT. Our OER are available free of charge to anyone. Make sure to subscribe - we are going to create 3000 more! The Fuse School have recently released a Chemistry Education project sponsored by Fuse, called 'The Chemistry Journey'. 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biology, recruited, barrier, enter, macrophages, infection, members\u003c/div\u003e\n\u003cdiv class='keyterms-toggle-buttons' data-identifier='Boclips::VideoDecorator60cb6b7455dff626bad57560'\u003e\n\u003cbutton aria-expanded='false' class='more btn-link' type='button'\u003e\n\u003cspan\u003eShow More\u003c/span\u003e\n\u003ci aria-hidden='true' class='fa-solid fa-caret-down ml5'\u003e\u003c/i\u003e\n\u003c/button\u003e\n\u003cbutton aria-expanded='true' class='less btn-link' style='display: none;' type='button'\u003e\n\u003cspan\u003eShow Less\u003c/span\u003e\n\u003ci aria-hidden='true' class='fa-solid fa-caret-up ml5'\u003e\u003c/i\u003e\n\u003c/button\u003e\n\u003c/div\u003e\n\u003c/div\u003e\n\u003c/div\u003e\n\u003cdiv aria-labelledby='classroom-considerations-heading' class='rp-info-section'\u003e\n\u003ch2 class='title' id='classroom-considerations-heading'\u003eClassroom Considerations\u003c/h2\u003e\n\u003cdiv class='classroom-considerations'\u003e\u003cdiv class='fai fa-solid fa-bell'\u003e\u003c/div\u003eBest For: Explaining a topic\u003c/div\u003e\u003cdiv class='classroom-considerations'\u003e\u003cdiv class='fai fa-solid fa-bell'\u003e\u003c/div\u003eVideo is ad-free\u003c/div\u003e \n\u003c/div\u003e\n\u003cdiv aria-labelledby='educator-ratings-heading' class='rp-info-section'\u003e\n\u003ch2 class='title sr-only' id='educator-ratings-heading'\u003eEducator Ratings\u003c/h2\u003e\n\u003cdiv id=\"educator-ratings-root\"\u003e\u003c/div\u003e\u003cdiv id=\"all-educator-ratings-root\"\u003e\u003c/div\u003e\u003cdiv id=\"educator-rating-form-root\"\u003e\u003c/div\u003e\n\u003c/div\u003e\n\u003c/div\u003e\n\u003cdiv class='rp-resource'\u003e\n\u003cdiv aria-label='Show resource details' class='rp-show-info' role='button' tabindex='0'\u003e\n\u003ci class='fai fa-solid fa-align-left'\u003e\u003c/i\u003e\nShow resource details\n\u003c/div\u003e\n\u003cdiv aria-label='Video player' class='player' id='player-wrapper' role='region'\u003e\n\u003cdiv 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