{"page":"\u003clink rel=\"stylesheet\" href=\"https://lessonplanet.com/assets/packs/css/resources-c03aa079.css\" /\u003e\n\u003clink rel=\"stylesheet\" href=\"https://lessonplanet.com/assets/packs/css/lp_boclips_stylesheets-517835be.css\" media=\"all\" /\u003e\n\u003cdiv data-title='Platelets \u0026amp; Blood Clotting' data-url='/boclips/videos/60cb6b6fcb8da013af6e9ee6' data-video-url='/boclips/videos/60cb6b6fcb8da013af6e9ee6' id='bo_player_modal'\u003e\n\u003cdiv class='boclips-resource-page modal-dialog panel-container'\u003e\n\u003cdiv class='react-notifications-root'\u003e\u003c/div\u003e\n\u003cdiv class='rp-header'\u003e\n\u003cdiv class='rp-type'\u003e\n\u003ci aria-hidden='true' class='fai fa-regular fa-circle-play'\u003e\u003c/i\u003e\nVideo\n\u003c/div\u003e\n\u003ch1 class='rp-title' id='video-title'\u003e\nPlatelets \u0026amp; Blood Clotting\n\u003c/h1\u003e\n\u003cdiv class='rp-actions'\u003e\n\u003cdiv class='mr-1'\u003e\n\u003ca class=\"btn btn-success\" data-posthog-event=\"Signup: LP Signup Activity\" data-posthog-location=\"body_link_boclips\" data-remote=\"true\" href=\"/subscription/new\"\u003e\u003cspan\u003e\u003cspan\u003eGet Free Access\u003c/span\u003e\u003cspan class=\"\"\u003e for 10 Days\u003c/span\u003e\u003cspan\u003e!\u003c/span\u003e\u003c/span\u003e\u003c/a\u003e\n\u003c/div\u003e\n\u003c/div\u003e\n\u003c/div\u003e\n\u003cdiv class='rp-body'\u003e\n\u003cdiv class='rp-info'\u003e\n\u003cdiv aria-label='Hide resource details' class='rp-hide-info' role='button' tabindex='0'\u003e\u0026times;\u003c/div\u003e\n\u003ci aria-label='Expand resource details' class='rp-expand-info fai fa-solid fa-up-right-and-down-left-from-center' role='button' tabindex='0'\u003e\u003c/i\u003e\n\u003ci aria-label='Compress resource details' class='rp-compress-info fai fa-solid fa-down-left-and-up-right-to-center' role='button' tabindex='0'\u003e\u003c/i\u003e\n\u003cdiv class='rp-rating'\u003e\n\u003cspan class='resource-pool'\u003e\n\u003cspan class='pool-label'\u003ePublisher:\u003c/span\u003e\n\u003cspan class='pool-name'\u003e\n\u003cspan class='text'\u003e\u003ca data-publisher-id=\"30356647\" href=\"/search?publisher_ids%5B%5D=30356647\"\u003eFuseSchool\u003c/a\u003e\u003c/span\u003e\n\u003c/span\u003e\n\u003c/span\u003e\n\u003c/div\u003e\n\u003cdiv class='rp-description'\u003e\n\u003cspan class='short-description'\u003eDo you remember tripping over as a kid and cutting your knee? And then like magic the bleeding suddenly stops? Have you ever wondered why this happens? Our body is very clever and produces substances to seal off the open wound. In this...\u003c/span\u003e\n\u003cspan class='full-description hide'\u003eDo you remember tripping over as a kid and cutting your knee? And then like magic the bleeding suddenly stops? Have you ever wondered why this happens? Our body is very clever and produces substances to seal off the open wound. In this video we are going to look at how and why blood clots. Clotting prevents us from bleeding to death, and also protects us from nasty disease-causing organisms, called pathogens, entering our body. When we injure ourselves, we can damage the blood vessels just below our skin. This can cause blood to either leak into our tissue and form a bruise, or, if the skin is broken to openly bleed. To prevent these horrible things happening, blood clotting occurs. So let’s have a look at how this happens. Starting with platelets. These are tiny cell fragments that float around in our blood. When a blood vessel is damaged, collagen is exposed. This collagen exposure attracts platelets to the injured area. The platelets then stick together to form a plug. They’ve quickly built a little barrier that stops us from losing too much blood. However, this platelet plug isn’t that strong. So it needs to be made stronger. A protein called fibrin does exactly that. In our blood there are soluble fibrinogen proteins. At a wound, these soluble fibrinogen proteins are exposed to outside chemicals that aren’t normally found in blood vessels. Like with the collagen and platelets, this exposure causes the fibrinogen proteins to turn into sticky fibrin fibres. The fibrin fibres form a mesh, holding all the platelets together and making a much stronger clot. More platelets, red blood cells and other components in our blood, all get stuck in the mesh making it even stronger. This clot stops more blood escaping the body. And also prevents nasty pathogens entering our body from the outside. The clot develops into a scab, which protects the wound as it heals and new layers of skin form underneath. So really, all a scab is is just platelets trapped in the fibrin mesh! When the new skin is fully formed, the scab will fall off, revealing the lovely brand new skin underneath. Remember that I said the exposure to collagen causes the platelets to stick together? And the exposure to outside chemicals causes the fibrinogen to turn into sticky fibrin? Both the platelets and the fibrin only become sticky AFTER the exposure. This means that in a normal, healthy blood vessel they won’t randomly cause clots. So from this video, you should understand the magic of blood clotting. Platelets are first to the scene closely followed by fibrin fibres. 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fibrin, prevent, science, sticky, wound, remember, biology, clotting, fiber nowjan, fibrin fibers\u003c/div\u003e\n\u003cdiv class='keyterms-toggle-buttons' data-identifier='Boclips::VideoDecorator60cb6b6fcb8da013af6e9ee6'\u003e\n\u003cbutton aria-expanded='false' class='more btn-link' type='button'\u003e\n\u003cspan\u003eShow More\u003c/span\u003e\n\u003ci aria-hidden='true' class='fa-solid fa-caret-down ml5'\u003e\u003c/i\u003e\n\u003c/button\u003e\n\u003cbutton aria-expanded='true' class='less btn-link' style='display: none;' type='button'\u003e\n\u003cspan\u003eShow Less\u003c/span\u003e\n\u003ci aria-hidden='true' class='fa-solid fa-caret-up ml5'\u003e\u003c/i\u003e\n\u003c/button\u003e\n\u003c/div\u003e\n\u003c/div\u003e\n\u003c/div\u003e\n\u003cdiv aria-labelledby='classroom-considerations-heading' class='rp-info-section'\u003e\n\u003ch2 class='title' id='classroom-considerations-heading'\u003eClassroom Considerations\u003c/h2\u003e\n\u003cdiv 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