{"page":"<link rel=\"stylesheet\" href=\"https://lessonplanet.com/assets/packs/css/resources-572d6a42.css\" />\n<link rel=\"stylesheet\" href=\"https://lessonplanet.com/assets/packs/css/lp_boclips_stylesheets-f4d0de30.css\" media=\"all\" />\n<div data-title='Which Will Kill You First?' data-url='/boclips/videos/60665fd63c9f286c5d9e6bc2' data-video-url='/boclips/videos/60665fd63c9f286c5d9e6bc2' id='bo_player_modal'>\n<div class='boclips-resource-page modal-dialog panel-container'>\n<div class='react-notifications-root'></div>\n<div class='rp-header'>\n<div class='rp-type'>\n<i aria-hidden='true' class='fai fa-regular fa-circle-play'></i>\nVideo\n</div>\n<h1 class='rp-title' id='video-title'>\nWhich Will Kill You First?\n</h1>\n<div class='rp-actions'>\n<div class='mr-1'>\n<a class=\"btn btn-success\" data-posthog-event=\"Signup: LP Signup Activity\" data-posthog-location=\"body_link_boclips\" data-remote=\"true\" href=\"/subscription/new\"><span><span>Get Free Access</span><span class=\"\"> for 10 Days</span><span>!</span></span></a>\n</div>\n</div>\n</div>\n<div class='rp-body'>\n<div class='rp-info'>\n<div aria-label='Hide resource details' class='rp-hide-info' role='button' tabindex='0'>&times;</div>\n<i aria-label='Expand resource details' class='rp-expand-info fai fa-solid fa-up-right-and-down-left-from-center' role='button' tabindex='0'></i>\n<i aria-label='Compress resource details' class='rp-compress-info fai fa-solid fa-down-left-and-up-right-to-center' role='button' tabindex='0'></i>\n<div class='rp-rating'>\n<span class='resource-pool'>\n<span class='pool-label'>Publisher:</span>\n<span class='pool-name'>\n<span class='text'><a data-publisher-id=\"30358007\" href=\"/search?publisher_ids%5B%5D=30358007\">MinuteEarth</a></span>\n</span>\n</span>\n</div>\n<div class='rp-description'>\n<span class='short-description'>Get Surfshark VPN at and enter code MINUTEEARTH for 83% off and 3 extra months free! The body can get a whole lot colder - but not a whole lot hotter - before we die. Why is that? LEARN MORE ************** To learn more about this topic,...</span>\n<span class='full-description hide'>Get Surfshark VPN <a href='https://surfshark.deals/minuteearth' target='_blank' rel='nofollow'>at</a> and enter code MINUTEEARTH for 83% off and 3 extra months free! The body can get a whole lot colder - but not a whole lot hotter - before we die. Why is that? LEARN MORE ************** To learn more about this topic, start your googling with these keywords: Hyperthermia: a medical condition where an individual's body temperature is elevated beyond normal Hypothermia: a medical doncition that occurs when an individual's body loses heat faster than it can produce heat, causing a dangerously low body temperature Thermoregulation is the ability of an organism to keep its body temperature within certain boundaries, even when the surrounding temperature is very different Denaturation: the alteration of a protein shape through some form of external stress (for example, heat), so that it can no longer carry out its cellular function If you liked this week’s video, you might also like: A great article from Outside on <a href='https://www.outsideonline.com/2398105/heat-stroke-signs-symptoms' target='_blank' rel='nofollow'>hyperthermia</a> Learn more about the woman who survived the lowest known body <a href='https://www.atlasobscura.com/articles/the-woman-who-survived-the-lowest-body-temperature-ever' target='_blank' rel='nofollow'>temp</a> SUPPORT MINUTEEARTH ************************** If you like what we do, you can help us!: - Become our <a href='https://patreon.com/MinuteEarth' target='_blank' rel='nofollow'>patron</a> - Share this video with your friends and family - Leave us a comment (we read them!) CREDITS ********* Kate Yoshida | Script Writer, Narrator and Director Sarah Berman | Illustration, Video Editing and Animation Nathaniel Schroeder | Music MinuteEarth is produced by Neptune Studios <a href='https://neptunestudios.info' target='_blank' rel='nofollow'>LLC</a> OUR STAFF ************ Sarah Berman • Arcadi Garcia Rius David Goldenberg • Julián Gustavo Gómez Melissa Hayes • Alex Reich • Henry Reich Peter Reich • Ever Salazar • Kate Yoshida OUR LINKS ************ <a href='https://youtube.com/MinuteEarth' target='_blank' rel='nofollow'>Youtube |</a> <a href='https://tiktok.com/@minuteearth' target='_blank' rel='nofollow'>TikTok |</a> <a href='https://twitter.com/MinuteEarth' target='_blank' rel='nofollow'>Twitter |</a> <a href='https://instagram.com/minute_earth' target='_blank' rel='nofollow'>Instagram |</a> <a href='https://facebook.com/Minuteearth' target='_blank' rel='nofollow'>Facebook |</a> <a href='https://minuteearth.com' target='_blank' rel='nofollow'>Website |</a> Apple <a href='https://podcasts.apple.com/us/podcast/minuteearth/id649211176' target='_blank' rel='nofollow'>Podcasts|</a> REFERENCES ************** Lepock JR (2004). Role of nuclear protein denaturation and aggregation in thermal radiosensitization, International Journal of Hyperthermia, 20:2, 115-<a href='https://www.tandfonline.com/doi/abs/10.1080/02656730310001637334' target='_blank' rel='nofollow'>130,</a> Leuenberger, P, Ganscha S, Kahraman A, Cappelletti V, PJ Boersema, Mering Cv, Claassen M, Picotti P (2017). Cell-wide analysis of protein thermal unfolding reveals determinants of thermostability Science, 355: <a href='https://science.sciencemag.org/content/355/6327/eaai7825' target='_blank' rel='nofollow'>eaai7825.</a> Roti Roti J (2008) Cellular responses to hyperthermia (40–46 degrees C): cell killing and molecular events. International Journal of Hyperthermia 24(1): 3–<a href='https://www.tandfonline.com/doi/full/10.1080/02656730701769841' target='_blank' rel='nofollow'>15.</a> Sawka MN, Leon LR, Montain SJ, Sonna LA (2011). Integrated physiological mechanisms of exercise performance, adaptation, and maladaptation to heat stress. Comprehensive Physiology 1: 1883-<a href='https://onlinelibrary.wiley.com/doi/abs/10.1002/cphy.c100082' target='_blank' rel='nofollow'>1928.</a> Slovis CM, Anderson GF, Casolaro A (1982). Survival in a heat stroke victim with a core temperature in excess of 46.5 C. Annals of Emergency Medicine 11(5):269-<a href='https://linkinghub.elsevier.com/retrieve/pii/S0196-0644(82)80099-1' target='_blank' rel='nofollow'>271.</a></span>\n</div>\n<div class='action-container flex justify-between'>\n<button aria-expanded='false' aria-label='Read more description' class='rp-full-description' type='button'>\n<i class='fai fa-solid fa-align-left'></i>\n<span id='read_more'>Read More</span>\n</button>\n<div class='rp-report'>\n</div>\n</div>\n<div aria-labelledby='resource-details-heading' class='rp-info-section'>\n<h2 class='title' id='resource-details-heading'>Resource Details</h2>\n<div class='rp-resource-details clearfix'>\n<div class='detail'>\n<dl>\n<dt>Curator Rating</dt>\n<dd><span class=\"star-rating\" aria-label=\"5.0 out of 5 stars\" role=\"img\"><i class=\"fa-solid fa-star text-action\" aria-hidden=\"true\"></i><i class=\"fa-solid fa-star text-action\" aria-hidden=\"true\"></i><i class=\"fa-solid fa-star text-action\" aria-hidden=\"true\"></i><i class=\"fa-solid fa-star text-action\" aria-hidden=\"true\"></i><i class=\"fa-solid fa-star text-action\" aria-hidden=\"true\"></i></span></dd>\n</dl>\n</div>\n<div class='detail'>\n<dl>\n<dt class=\"educator-rating-title\">Educator Rating</dt><dd><div class=\"educator-rating-details\" data-path=\"/educator_ratings/rrp_data?resourceable_id=105809&amp;resourceable_type=Boclips%3A%3AVideoMetadata\"><span class=\"not-yet-rated\">Not yet Rated</span></div></dd>\n</dl>\n</div>\n<div class='detail'>\n<dl>\n<dt>Grade</dt><dd title=\"Grade\">12th - Higher Ed</dd>\n</dl>\n</div>\n<div class='detail'>\n<dl>\n<dt>Subjects</dt><dd><span><a href=\"/search?grade_ids%5B%5D=258&amp;grade_ids%5B%5D=259&amp;search_tab_id=1&amp;subject_ids%5B%5D=365221\">Science</a></span></dd><dd class=\"text-muted\"><i class=\"fa-solid fa-lock mr5\"></i>3 more...</dd>\n</dl>\n</div>\n<div class='detail'>\n<dl>\n<dt>Media Type</dt><dd><span><a href=\"/search?grade_ids%5B%5D=258&amp;grade_ids%5B%5D=259&amp;search_tab_id=2&amp;type_ids%5B%5D=4543647\">Instructional Videos</a></span></dd>\n</dl>\n</div>\n<div class='detail'>\n<dl>\n<dt>Source:</dt>\n<dd></dd>\n</dl>\n</div>\n<div class='detail'>\n<dl>\n<dt>Date</dt>\n<dd>2021</dd>\n</dl>\n</div>\n<div class='detail'>\n<dl>\n<i aria-hidden='true' class='fai fa-solid fa-language'></i>\n\n</dl>\n</div>\n<div class='detail'>\n<dl>\n<dt>Audiences</dt><dd><span><a href=\"/search?audience_ids%5B%5D=371079&amp;grade_ids%5B%5D=258&amp;grade_ids%5B%5D=259&amp;search_tab_id=1\">For Teacher Use</a></span></dd><dd class=\"text-muted\"><i class=\"fa-solid fa-lock mr5\"></i>2 more...</dd>\n</dl>\n</div>\n<div class='detail'>\n<dl>\n\n</dl>\n</div>\n</div>\n</div>\n<div aria-labelledby='educator-ratings-heading' class='rp-info-section'>\n<h2 class='title sr-only' id='educator-ratings-heading'>Educator Ratings</h2>\n<div id=\"educator-ratings-root\"></div><div id=\"all-educator-ratings-root\"></div><div id=\"educator-rating-form-root\"></div>\n</div>\n</div>\n<div class='rp-resource'>\n<div aria-label='Show resource details' class='rp-show-info' role='button' tabindex='0'>\n<i class='fai fa-solid fa-align-left'></i>\nShow resource details\n</div>\n<div aria-label='Video player' class='player ie' id='player-wrapper' role='region'>\n<div class='relative container mx-auto' id='lp-boclips-visitor-thumbnail'>\n<a class=\"block\" data-html=\"true\" data-placement=\"bottom\" data-trigger=\"click\" data-content=\"<div class=&quot;text-center py-2&quot;><a class=&quot;bold&quot; href=&quot;/auth/users/sign_in&quot;>Sign in</a> or <a class=&quot;bold text-danger&quot; data-posthog-event=&quot;Signup: LP Signup Activity&quot; data-posthog-location=&quot;body_link_boclips&quot; data-remote=&quot;true&quot; href=&quot;/subscription/new&quot;>Join Now</a></div>\" data-title=\"Get Full Access\" data-container=\"body\" rel=\"popover\" tabindex=\"0\" aria-label=\"Play video: Which Will Kill You First?\" href=\"/subscription/new\"><img class=\"resource-img img-thumbnail img-responsive z-10 lp-boclips-thumbnail w-full h-full lozad\" alt=\"Which Will Kill You First?\" title=\"Which Will Kill You First?\" onError=\"handleImageNotLoadedError(this)\" data-default-image=\"https://static.lp.lexp.cloud/images/attachment_defaults/resource/large/missing.png\" data-src=\"https://static.lp.lexp.cloud/images/attachment_defaults/resource/large/missing.png\" width=\"315\" height=\"220\" src=\"data:image/png;base64,R0lGODlhAQABAAD/ACwAAAAAAQABAAACADs\" />\n<span aria-hidden='true' class='flex justify-center items-center bg-white rounded-full w-16 h-16 absolute top-1/2 left-1/2 -mt-8 -ml-8 cursor-pointer z-0 border-2 border-primary drop-shadow-md lp-boclips-thumbnail-playBtn'>\n<i class='fa-solid fa-play text-primary text-3xl ml-1 drop-shadow-xl'></i>\n</span>\n</a></div>\n</div>\n</div>\n</div>\n</div>\n</div>\n"}