{"page":"<link rel=\"stylesheet\" href=\"https://lessonplanet.com/assets/packs/css/resources-572d6a42.css\" />\n<link rel=\"stylesheet\" href=\"https://lessonplanet.com/assets/packs/css/lp_boclips_stylesheets-f4d0de30.css\" media=\"all\" />\n<div data-title='How mitochondrial diseases are inherited' data-url='/boclips/videos/5cdb02b5056744344d090f7d' data-video-url='/boclips/videos/5cdb02b5056744344d090f7d' id='bo_player_modal'>\n<div class='boclips-resource-page modal-dialog panel-container'>\n<div class='react-notifications-root'></div>\n<div class='rp-header'>\n<div class='rp-type'>\n<i aria-hidden='true' class='fai fa-regular fa-circle-play'></i>\nVideo\n</div>\n<h1 class='rp-title' id='video-title'>\nHow mitochondrial diseases are inherited\n</h1>\n<div class='rp-actions'>\n<div class='mr-1'>\n<a class=\"btn btn-success\" data-posthog-event=\"Signup: LP Signup Activity\" data-posthog-location=\"body_link_boclips\" data-remote=\"true\" href=\"/subscription/new\"><span><span>Get Free Access</span><span class=\"\"> for 10 Days</span><span>!</span></span></a>\n</div>\n</div>\n</div>\n<div class='rp-body'>\n<div class='rp-info'>\n<div aria-label='Hide resource details' class='rp-hide-info' role='button' tabindex='0'>&times;</div>\n<i aria-label='Expand resource details' class='rp-expand-info fai fa-solid fa-up-right-and-down-left-from-center' role='button' tabindex='0'></i>\n<i aria-label='Compress resource details' class='rp-compress-info fai fa-solid fa-down-left-and-up-right-to-center' role='button' tabindex='0'></i>\n<div class='rp-rating'>\n<span class='resource-pool'>\n<span class='pool-label'>Publisher:</span>\n<span class='pool-name'>\n<span class='text'><a data-publisher-id=\"30356011\" href=\"/search?publisher_ids%5B%5D=30356011\">Curated Video</a></span>\n</span>\n</span>\n</div>\n<div class='rp-description'>\n<span class='short-description'>In this video, Professor Rob Lue explains how mitochondrial diseases are inherited and discusses the threshold effect and its implications for mitochondrial disease inheritance. *** Sign-up for the course “Cell Biology: Mitochondria” on...</span>\n<span class='full-description hide'>In this video, Professor Rob Lue explains how mitochondrial diseases are inherited and discusses the threshold effect and its implications for mitochondrial disease inheritance. *** Sign-up for the course “Cell Biology: Mitochondria” on <a href='https://www.edx.org/course/cell-biology-mitochondria-harvardx-mcb64-1x' target='_blank' rel='nofollow'>edX</a> The cell is a powerful case study to help us explore the functional logic of living systems. All organisms, from single-celled algae to complex multicellular organisms like us, are made up of cells. In this course, you will learn the how and why of biology by exploring the function of the molecular components of cells, and how these cellular components are organized in a complex hierarchy. This course is designed to explore the fundamentals of cell biology. The overarching goal is for learners to understand, from a human-centered perspective, that cells are evolving ensembles of macromolecules that in turn form complex communities in tissues, organs, and multicellular organisms. We will focus, in particular, on the mitochondrion, the organelle that powers the cell. In this context, we will look at the processes of cell metabolism. Finally, we will examine the F1F0 ATP synthase, the molecular machine that is responsible for the synthesis of most of the ATP that your cells require to do work. To underscore the importance of cell biology to our lives, we will address questions of development and disease and implications of science in society. By the end of four weeks, we hope learners will have a deep intuition for the functional logic of a cell. Together we will ask how do things work within a cell, why do they work the way they do, and how are we impacted? Join us as we explore the extraordinary and wonderfully dynamic world of the cell. What you'll learn: - How the internal structure and organization of a cell provides an understanding of how and why a cell works - The role mitochondria play in the cell and why it is important for a cell to make ATP - How cells metabolize food to provide the molecules necessary for mitochondrial function - How the structure of the F1F0 ATP synthase leads to the production of ATP - What experimental techniques are used to investigate mitochondrial structure and function in the laboratory *** HarvardX is a Harvard University strategic initiative, to enable faculty to build and create open online learning experiences for the public, and to enable groundbreaking research in online pedagogies. Be sure to subscribe to HarvardX on YouTube to check out more great videos from Harvard.</span>\n</div>\n<div class='action-container flex justify-between'>\n<button aria-expanded='false' aria-label='Read more description' class='rp-full-description' type='button'>\n<i class='fai fa-solid fa-align-left'></i>\n<span id='read_more'>Read More</span>\n</button>\n<div class='rp-report'>\n</div>\n</div>\n<div aria-labelledby='resource-details-heading' class='rp-info-section'>\n<h2 class='title' id='resource-details-heading'>Resource Details</h2>\n<div class='rp-resource-details clearfix'>\n<div class='detail'>\n<dl>\n<dt>Curator Rating</dt>\n<dd><span class=\"star-rating\" aria-label=\"4.0 out of 5 stars\" role=\"img\"><i class=\"fa-solid fa-star text-action\" aria-hidden=\"true\"></i><i class=\"fa-solid fa-star text-action\" aria-hidden=\"true\"></i><i class=\"fa-solid fa-star text-action\" aria-hidden=\"true\"></i><i class=\"fa-solid fa-star text-action\" aria-hidden=\"true\"></i><i class=\"fa-regular fa-star text-action\" aria-hidden=\"true\"></i></span></dd>\n</dl>\n</div>\n<div class='detail'>\n<dl>\n<dt class=\"educator-rating-title\">Educator Rating</dt><dd><div class=\"educator-rating-details\" data-path=\"/educator_ratings/rrp_data?resourceable_id=86463&amp;resourceable_type=Boclips%3A%3AVideoMetadata\"><span class=\"not-yet-rated\">Not yet Rated</span></div></dd>\n</dl>\n</div>\n<div class='detail'>\n<dl>\n<dt>Grade</dt><dd title=\"Grade\">9th - 11th</dd>\n</dl>\n</div>\n<div class='detail'>\n<dl>\n<dt>Subjects</dt><dd><span><a href=\"/search?keywords=time+lines&amp;page=38&amp;search_tab_id=1&amp;subject_ids%5B%5D=1216220\">All Subjects</a></span></dd>\n</dl>\n</div>\n<div class='detail'>\n<dl>\n<dt>Media Type</dt><dd><span><a href=\"/search?keywords=time+lines&amp;page=38&amp;search_tab_id=2&amp;type_ids%5B%5D=4543647\">Instructional Videos</a></span></dd>\n</dl>\n</div>\n<div class='detail'>\n<dl>\n<dt>Source:</dt>\n<dd></dd>\n</dl>\n</div>\n<div class='detail'>\n<dl>\n<dt>Date</dt>\n<dd>2019</dd>\n</dl>\n</div>\n<div class='detail'>\n<dl>\n<i aria-hidden='true' class='fai fa-solid fa-language'></i>\n\n</dl>\n</div>\n<div class='detail'>\n<dl>\n<dt>Audiences</dt><dd><span><a href=\"/search?audience_ids%5B%5D=371079&amp;keywords=time+lines&amp;page=38&amp;search_tab_id=1\">For Teacher Use</a></span></dd><dd class=\"text-muted\"><i class=\"fa-solid fa-lock mr5\"></i>2 more...</dd>\n</dl>\n</div>\n<div class='detail'>\n<dl>\n\n</dl>\n</div>\n</div>\n</div>\n<div aria-labelledby='educator-ratings-heading' class='rp-info-section'>\n<h2 class='title sr-only' id='educator-ratings-heading'>Educator Ratings</h2>\n<div id=\"educator-ratings-root\"></div><div id=\"all-educator-ratings-root\"></div><div id=\"educator-rating-form-root\"></div>\n</div>\n</div>\n<div class='rp-resource'>\n<div aria-label='Show resource details' class='rp-show-info' role='button' tabindex='0'>\n<i class='fai fa-solid fa-align-left'></i>\nShow resource details\n</div>\n<div aria-label='Video player' class='player' id='player-wrapper' role='region'>\n<div class='relative container mx-auto' id='lp-boclips-visitor-thumbnail'>\n<a class=\"block\" data-html=\"true\" data-placement=\"bottom\" data-trigger=\"click\" data-content=\"<div class=&quot;text-center py-2&quot;><a class=&quot;bold&quot; href=&quot;/auth/users/sign_in&quot;>Sign in</a> or <a class=&quot;bold text-danger&quot; data-posthog-event=&quot;Signup: LP Signup Activity&quot; data-posthog-location=&quot;body_link_boclips&quot; data-remote=&quot;true&quot; href=&quot;/subscription/new&quot;>Join Now</a></div>\" data-title=\"Get Full Access\" data-container=\"body\" rel=\"popover\" tabindex=\"0\" aria-label=\"Play video: How mitochondrial diseases are inherited\" href=\"/subscription/new\"><img class=\"resource-img img-thumbnail img-responsive z-10 lp-boclips-thumbnail w-full h-full lozad\" alt=\"How mitochondrial diseases are inherited\" title=\"How mitochondrial diseases are inherited\" onError=\"handleImageNotLoadedError(this)\" data-default-image=\"https://static.lp.lexp.cloud/images/attachment_defaults/resource/large/missing.png\" data-src=\"https://static.lp.lexp.cloud/images/attachment_defaults/resource/large/missing.png\" width=\"315\" height=\"220\" src=\"data:image/png;base64,R0lGODlhAQABAAD/ACwAAAAAAQABAAACADs\" />\n<span aria-hidden='true' class='flex justify-center items-center bg-white rounded-full w-16 h-16 absolute top-1/2 left-1/2 -mt-8 -ml-8 cursor-pointer z-0 border-2 border-primary drop-shadow-md lp-boclips-thumbnail-playBtn'>\n<i class='fa-solid fa-play text-primary text-3xl ml-1 drop-shadow-xl'></i>\n</span>\n</a></div>\n</div>\n</div>\n</div>\n</div>\n</div>\n"}