{"page":"\u003clink rel=\"stylesheet\" href=\"https://lessonplanet.com/assets/packs/css/resources-572d6a42.css\" /\u003e\n\u003clink rel=\"stylesheet\" href=\"https://lessonplanet.com/assets/packs/css/lp_boclips_stylesheets-f4d0de30.css\" media=\"all\" /\u003e\n\u003cdiv data-title='Eye study may detect early stage Alzheimer\u0026#39;s' data-url='/boclips/videos/5c54cb06d8eafeecae1a0a89' data-video-url='/boclips/videos/5c54cb06d8eafeecae1a0a89' id='bo_player_modal'\u003e\n\u003cdiv class='boclips-resource-page modal-dialog panel-container'\u003e\n\u003cdiv class='react-notifications-root'\u003e\u003c/div\u003e\n\u003cdiv class='rp-header'\u003e\n\u003cdiv class='rp-type'\u003e\n\u003ci aria-hidden='true' class='fai fa-regular fa-circle-play'\u003e\u003c/i\u003e\nVideo\n\u003c/div\u003e\n\u003ch1 class='rp-title' id='video-title'\u003e\nEye study may detect early stage Alzheimer\u0026#39;s\n\u003c/h1\u003e\n\u003cdiv class='rp-actions'\u003e\n\u003cdiv class='mr-1'\u003e\n\u003ca class=\"btn btn-success\" data-posthog-event=\"Signup: LP Signup Activity\" data-posthog-location=\"body_link_boclips\" data-remote=\"true\" href=\"/subscription/new\"\u003e\u003cspan\u003e\u003cspan\u003eGet Free Access\u003c/span\u003e\u003cspan class=\"\"\u003e for 10 Days\u003c/span\u003e\u003cspan\u003e!\u003c/span\u003e\u003c/span\u003e\u003c/a\u003e\n\u003c/div\u003e\n\u003c/div\u003e\n\u003c/div\u003e\n\u003cdiv class='rp-body'\u003e\n\u003cdiv class='rp-info'\u003e\n\u003cdiv aria-label='Hide resource details' class='rp-hide-info' role='button' tabindex='0'\u003e\u0026times;\u003c/div\u003e\n\u003ci aria-label='Expand resource details' class='rp-expand-info fai fa-solid fa-up-right-and-down-left-from-center' role='button' tabindex='0'\u003e\u003c/i\u003e\n\u003ci aria-label='Compress resource details' class='rp-compress-info fai fa-solid fa-down-left-and-up-right-to-center' role='button' tabindex='0'\u003e\u003c/i\u003e\n\u003cdiv class='rp-rating'\u003e\n\u003cspan class='resource-pool'\u003e\n\u003cspan class='pool-label'\u003ePublisher:\u003c/span\u003e\n\u003cspan class='pool-name'\u003e\n\u003cspan class='text'\u003e\u003ca data-publisher-id=\"30356011\" href=\"/search?publisher_ids%5B%5D=30356011\"\u003eCurated Video\u003c/a\u003e\u003c/span\u003e\n\u003c/span\u003e\n\u003c/span\u003e\n\u003c/div\u003e\n\u003cdiv class='rp-description'\u003e\n\u003cspan class='short-description'\u003eLEAD IN: Scientists studying Alzheimer's are hoping to turn an eye tracking device into an early warning signal for the disease.Our eye movements can reveal secrets about the health of our brains and the way it may be...\u003c/span\u003e\n\u003cspan class='full-description hide'\u003eLEAD IN: Scientists studying Alzheimer's are hoping to turn an eye tracking device into an early warning signal for the disease.Our eye movements can reveal secrets about the health of our brains and the way it may be deteriorating.STORY-LINE: Sue Stafford is retired, but she is still healthy and active so she's putting her sharp eyes and quick brain at the disposal of scientists.Stafford is one of many who've helped these scientists at Lancaster University develop computer software for an eye tracker which shows how the volunteer is thinking.Text on a screen gives her instructions which she then follows.They all involve her concentrating on a video, or different coloured dots which appear and disappear before her eyes.How well Stafford does, is calculated by the device.Sensitive cameras follow every movement and her position is callibrated so that the results can be accurately measured.Each samples the eye, taking 500 pictures a second.The research is being run by Dr. Trevor Crawford and Doctor Thomas Wilcockson who believe what they've discovered so far means they're now ready to conduct trials.Lead scientist Dr. Trevor Crawford explains what's happening to Stafford saying: \"Every second it's sampling your eye and then it's doing a geometrical, mathematical calculation to work out exactly where you're looking and it's doing this at incredibly fast speeds. So this is all happening in real time, (to Stafford) now look to the centre, very good excellent.\"Wilcockson attracts the attention of the study participant with an object on the screen.He says: \"When this stimulus appears on the screen participants are drawn to it because they have task specific instructions related to this green circle, so in order to exercise conscious control over eye movements to look in the other direction requires some kind of cognitive control, an executive function and people with Alzheimer's disease are less readily able to follow the instructions and look away.\"Dementia Research, a government agency funded by the National Institute of Health Research is now helping the team to recruit patients to the study.The agency connects Alzheimer's and dementia patients who want to take part in the research, with studies across the UK.Dementia Research also connects healthy volunteers like Sue Stafford. The aim is to have three groups for a clinical trial.One will be patients with confirmed Alzheimer's disease, the second will have early signs of cognitive impairment and the third will be a healthy control group.The tests they're carrying out are called antisaccade tests.Crawford says his earlier studies have shown Alzheimer's patients have ' occular motor marker' or sight impairment which distinguishes them from patients with other dementias. To explain Crawford uses the analogy of driving a car.He says: \"For example when you're driving, there's lots of things happening, it's very important we can focus our attention where you want to go and ignore distracting information and this task looks at that ability.\"According to Crawford: \"You find in Alzheimer's disease, for some reason patients don't seem to be aware of the errors that they're making, so they get distracted and they fail to correct for that distraction.\"Crawford claims early results which haven't been confirmed by a full trial show they can distinguish between Alzheimer's disease and others like vascular dementia.The study aims to confirm this.The team believe by creating a very specific test they'll be able to develop an early diagnosis for Alzheimer's.Currently the disease can't be confirmed until the patients show symptoms.Crawford explains how our vision connects to the part of our brain affected by Alzheimer's.He says: \"The network, the neural network that controls how you move your eyes around the screen is distributed in different parts of the brain and some of those very same areas that are responsible for moving your eyes are also impaired in Alzheimer's disease so we know that Alzheimer's disease starts very, in a very small part of the brain, then it spreads gradually to other parts and some of those areas that it affects are areas that are involved in attention and memory and voluntary control and inhibitory control and these are all aspects of cognitive operations that are involved in controlling the eyes well.\"The team believe by creating a very specific test they'll be able to develop an early diagnosis for Alzheimer's.Currently the disease can't be confirmed until the patients show symptoms and there is no treatment.This means only three percent of dementia patients in the UK are motivated to join trials.Dementia Research is hoping to raise this to at least ten percent.Drugs are being trialled around the world and doctors believe intervening early may make a significant difference in slowing down the disease.It's urging more people to come forward.Sue Stafford is member of a worldwide organisation called the University of the Third Age.It provides courses, pass times and social occasions for older and elderly people.She looks at video of the British Queen's coronation in 1953 and answers question about what she sees.How many bald men are there?How many different colours can she see?Stafford says: \"Well I'm involved quite a lot with music, I sing in three choirs and I play the ukulele and I'm trying to play the guitar as well and I think that really, really helps. Singing I think is very good for your mental and physical wellbeing and I think learning any sort of musical instrument does help your memory and keep your brain active.\"After the tests the scientists can track exactly how their trial subjects have performed, superimposing the dots on the video they've watched.The UK is currently marking Dementia Awareness Week.The doctors and scientists hope it will attract more patients to want to make a direct contribution to fighting these diseases.LEAD IN: Scientists studying Alzheimer's are hoping to turn an eye tracking device into an early warning signal for the disease.Our eye movements can reveal secrets about the health of our brains and the way it may be deteriorating.STORY-LINE: Sue Stafford is retired, but she is still healthy and active so she's putting her sharp eyes and quick brain at the disposal of scientists.Stafford is one of many who've helped these scientists at Lancaster University develop computer software for an eye tracker which shows how the volunteer is thinking.Text on a screen gives her instructions which she then follows.They all involve her concentrating on a video, or different coloured dots which appear and disappear before her eyes.How well Stafford does, is calculated by the device.Sensitive cameras follow every movement and her position is callibrated so that the results can be accurately measured.Each samples the eye, taking 500 pictures a second.The research is being run by Dr. Trevor Crawford and Doctor Thomas Wilcockson who believe what they've discovered so far means they're now ready to conduct trials.Lead scientist Dr. Trevor Crawford explains what's happening to Stafford saying: \"Every second it's sampling your eye and then it's doing a geometrical, mathematical calculation to work out exactly where you're looking and it's doing this at incredibly fast speeds. So this is all happening in real time, (to Stafford) now look to the centre, very good excellent.\"Wilcockson attracts the attention of the study participant with an object on the screen.He says: \"When this stimulus appears on the screen participants are drawn to it because they have task specific instructions related to this green circle, so in order to exercise conscious control over eye movements to look in the other direction requires some kind of cognitive control, an executive function and people with Alzheimer's disease are less readily able to follow the instructions and look away.\"Dementia Research, a government agency funded by the National Institute of Health Research is now helping the team to recruit patients to the study.The agency connects Alzheimer's and dementia patients who want to take part in the research, with studies across the UK.Dementia Research also connects healthy volunteers like Sue Stafford. The aim is to have three groups for a clinical trial.One will be patients with confirmed Alzheimer's disease, the second will have early signs of cognitive impairment and the third will be a healthy control group.The tests they're carrying out are called antisaccade tests.Crawford says his earlier studies have shown Alzheimer's patients have ' occular motor marker' or sight impairment which distinguishes them from patients with other dementias. To explain Crawford uses the analogy of driving a car.He says: \"For example when you're driving, there's lots of things happening, it's very important we can focus our attention where you want to go and ignore distracting information and this task looks at that ability.\"According to Crawford: \"You find in Alzheimer's disease, for some reason patients don't seem to be aware of the errors that they're making, so they get distracted and they fail to correct for that distraction.\"Crawford claims early results which haven't been confirmed by a full trial show they can distinguish between Alzheimer's disease and others like vascular dementia.The study aims to confirm this.The team believe by creating a very specific test they'll be able to develop an early diagnosis for Alzheimer's.Currently the disease can't be confirmed until the patients show symptoms.Crawford explains how our vision connects to the part of our brain affected by Alzheimer's.He says: \"The network, the neural network that controls how you move your eyes around the screen is distributed in different parts of the brain and some of those very same areas that are responsible for moving your eyes are also impaired in Alzheimer's disease so we know that Alzheimer's disease starts very, in a very small part of the brain, then it spreads gradually to other parts and some of those areas that it affects are areas that are involved in attention and memory and voluntary control and inhibitory control and these are all aspects of cognitive operations that are involved in controlling the eyes well.\"The team believe by creating a very specific test they'll be able to develop an early diagnosis for Alzheimer's.Currently the disease can't be confirmed until the patients show symptoms and there is no treatment.This means only three percent of dementia patients in the UK are motivated to join trials.Dementia Research is hoping to raise this to at least ten percent.Drugs are being trialled around the world and doctors believe intervening early may make a significant difference in slowing down the disease.It's urging more people to come forward.Sue Stafford is member of a worldwide organisation called the University of the Third Age.It provides courses, pass times and social occasions for older and elderly people.She looks at video of the British Queen's coronation in 1953 and answers question about what she sees.How many bald men are there?How many different colours can she see?Stafford says: \"Well I'm involved quite a lot with music, I sing in three choirs and I play the ukulele and I'm trying to play the guitar as well and I think that really, really helps. Singing I think is very good for your mental and physical wellbeing and I think learning any sort of musical instrument does help your memory and keep your brain active.\"After the tests the scientists can track exactly how their trial subjects have performed, superimposing the dots on the video they've watched.The UK is currently marking Dementia Awareness Week.The doctors and scientists hope it will attract more patients to want to make a direct contribution to fighting these diseases.Lancaster, UK - 13 May 20161. Close of monitor showing tracker being calibrated to the eyes of the study volunteer2. Close of eye of study volunteer Sue Stafford 3. Close profile of Sue Stafford during tests 4. UPSOUND: (English) Dr. Trevor Crawford, director psychology, Centre for Age and Research, Lancaster University\"Every second it's sampling your eye and then it's doing a geometrical, mathematical calculation to work out exactly where you're looking and it's doing this at incredibly fast speeds. So this is all happening in real time, (to Stafford) now look to the centre, very good excellent.\"5. Close zoom in and out of Stafford's eye on monitor tracking device 6. Mid of study with Stafford during study supervised by Dr. Trevor Crawford and Dr. Thomas Wilcockson 7. SOUNDBITE: (English) Dr. Thomas Wilcockson, neuropsychologist, Lancaster University \"When this stimulus appears on the screen participants are drawn to it because they have task specific instructions related to this green circle, so in order to exercise conscious control over eye movements to look in the other direction requires some kind of cognitive control, an executive function and people with Alzheimer's disease are less readily able to follow the instructions and look away.\"8. Close of green circle appearing on monitor then instructions 9. SOUNDBITE: (English) Dr. Trevor Crawford, director psychology, Centre for Age and Research, Lancaster University\"For example when you're driving, there's lots of things happening, it's very important we can focus our attention where you want to go and ignore distracting information and this task looks at that ability.\"10. Close of Stafford's face in frame with her eyes moving to watch, or look away from circles 11. SOUNDBITE: (English) Dr. Trevor Crawford, director psychology, Centre for Age and Research, Lancaster University \"You find in Alzheimer's disease, for some reason patients don't seem to be aware of the errors that they're making, so they get distracted and they fail to correct for that distraction.\"12. Mid rear view of Stafford looking at screen 13. Close of black screen monitor with green dot appearing 14. Close of tracking device monitor 15. Close pull focus on camera lens16. Close rear view of Stafford during study 17. Close pan of text giving task instructions on the screen 18. Various of dots and text alternating on screen at random  19. Close of Stafford watching 20. Wide of study supervised by Crawford and conducted by Wilcockson 21. Close of tracker showing recalibration of eye 22. Various close of dots and text 23. SOUNDBITE: (English) Dr. Trevor Crawford, director psychology, Centre for Age and Research, Lancaster University \"The network, the neural network that controls how you move your eyes around the screen is distributed in different parts of the brain and some of those very same areas that are responsible for moving your eyes are also impaired in Alzheimer's disease so we know that Alzheimer's disease starts very, in a very small part of the brain, then it spreads gradually to other parts and some of those areas that it affects are areas that are involved in attention and memory and voluntary control and inhibitory control and these are all aspects of cognitive operations that are involved in controlling the eyes well.\"24. UPSOUND: (English) Dr. Thomas Wilcockson, neuropsychologist, Lancaster University (speaking to Stafford during study)\"Now whilst watching the Queen (Elizabeth II of Britain) video I'd like you to look and see what colours all the clothes are within the room. I'd like you to remember as much detail about the different coloured clothes as you can.\" 25. Wide slow tracking shot out of study group watching sound of Queen Elizabeth being crowned 26. Mid side view of Stafford and Wilcockson 27. Close of picture with pink dots showing where Stafford's eyes track across the screen 28. UPSOUND: (English) Dr. Thomas Wilcockson, neuropsychologist, Lancaster University (speaking to Stafford during study)\"How many bald men could you see?\"29. UPSOUND: (English) Sue Stafford study volunteer \"Well I counted thirteen.\"30. UPSOUND: (English) Dr. Thomas Wilcockson, neuropsychologist, Lancaster University (speaking to Stafford during study)\"Very good thank you.\"31. SOUNDBITE: (English) Sue Stafford study volunteer \"Well I'm involved quite a lot with music, I sing in three choirs and I play the ukulele and I'm trying to play the guitar as well and I think that really, really helps. Singing I think is very good for your mental and physical wellbeing and I think learning any sort of musical instrument does help your memory and keep your brain active.\"32. Close of Stafford watching video and being asked how many bald men were in the room, she answers: \"About thirteen.\"LENGTH: 5.30\u003c/span\u003e\n\u003c/div\u003e\n\u003cdiv class='action-container flex justify-between'\u003e\n\u003cbutton aria-expanded='false' aria-label='Read more description' class='rp-full-description' type='button'\u003e\n\u003ci class='fai fa-solid fa-align-left'\u003e\u003c/i\u003e\n\u003cspan id='read_more'\u003eRead More\u003c/span\u003e\n\u003c/button\u003e\n\u003cdiv class='rp-report'\u003e\n\u003c/div\u003e\n\u003c/div\u003e\n\u003cdiv aria-labelledby='resource-details-heading' class='rp-info-section'\u003e\n\u003ch2 class='title' id='resource-details-heading'\u003eResource Details\u003c/h2\u003e\n\u003cdiv class='rp-resource-details clearfix'\u003e\n\u003cdiv class='detail'\u003e\n\u003cdl\u003e\n\u003cdt\u003eCurator Rating\u003c/dt\u003e\n\u003cdd\u003e\u003cspan class=\"star-rating\" aria-label=\"3.5 out of 5 stars\" role=\"img\"\u003e\u003ci 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details\n\u003c/div\u003e\n\u003cdiv aria-label='Video player' class='player' id='player-wrapper' role='region'\u003e\n\u003cdiv class='relative container mx-auto' id='lp-boclips-visitor-thumbnail'\u003e\n\u003ca class=\"block\" data-html=\"true\" data-placement=\"bottom\" data-trigger=\"click\" data-content=\"\u003cdiv class=\u0026quot;text-center py-2\u0026quot;\u003e\u003ca class=\u0026quot;bold\u0026quot; href=\u0026quot;/auth/users/sign_in\u0026quot;\u003eSign in\u003c/a\u003e or \u003ca class=\u0026quot;bold text-danger\u0026quot; data-posthog-event=\u0026quot;Signup: LP Signup Activity\u0026quot; data-posthog-location=\u0026quot;body_link_boclips\u0026quot; data-remote=\u0026quot;true\u0026quot; href=\u0026quot;/subscription/new\u0026quot;\u003eJoin Now\u003c/a\u003e\u003c/div\u003e\" data-title=\"Get Full Access\" data-container=\"body\" rel=\"popover\" tabindex=\"0\" aria-label=\"Play video: Eye study may detect early stage Alzheimer\u0026#39;s\" href=\"/subscription/new\"\u003e\u003cimg class=\"resource-img img-thumbnail img-responsive z-10 lp-boclips-thumbnail w-full h-full lozad\" alt=\"Eye study may detect early stage Alzheimer\u0026#39;s\" title=\"Eye study may detect early stage Alzheimer\u0026#39;s\" onError=\"handleImageNotLoadedError(this)\" data-default-image=\"https://static.lp.lexp.cloud/images/attachment_defaults/resource/large/missing.png\" data-src=\"https://static.lp.lexp.cloud/images/attachment_defaults/resource/large/missing.png\" width=\"315\" height=\"220\" src=\"data:image/png;base64,R0lGODlhAQABAAD/ACwAAAAAAQABAAACADs\" /\u003e\n\u003cspan aria-hidden='true' class='flex justify-center items-center bg-white rounded-full w-16 h-16 absolute top-1/2 left-1/2 -mt-8 -ml-8 cursor-pointer z-0 border-2 border-primary drop-shadow-md lp-boclips-thumbnail-playBtn'\u003e\n\u003ci class='fa-solid fa-play text-primary text-3xl ml-1 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