{"page":"\u003clink rel=\"stylesheet\" href=\"https://lessonplanet.com/assets/packs/css/resources-572d6a42.css\" /\u003e\n\u003clink rel=\"stylesheet\" href=\"https://lessonplanet.com/assets/packs/css/lp_boclips_stylesheets-f4d0de30.css\" media=\"all\" /\u003e\n\u003cdiv data-title='ITALY: CHILDREN WHO FEEL NO PAIN COULD HOLD KEY TO COMMON DISEASES' data-url='/boclips/videos/5c54c483d8eafeecae1695d3' data-video-url='/boclips/videos/5c54c483d8eafeecae1695d3' id='bo_player_modal'\u003e\n\u003cdiv class='boclips-resource-page modal-dialog panel-container'\u003e\n\u003cdiv class='react-notifications-root'\u003e\u003c/div\u003e\n\u003cdiv class='rp-header'\u003e\n\u003cdiv class='rp-type'\u003e\n\u003ci aria-hidden='true' class='fai fa-regular fa-circle-play'\u003e\u003c/i\u003e\nVideo\n\u003c/div\u003e\n\u003ch1 class='rp-title' id='video-title'\u003e\nITALY: CHILDREN WHO FEEL NO PAIN COULD HOLD KEY TO COMMON DISEASES\n\u003c/h1\u003e\n\u003cdiv class='rp-actions'\u003e\n\u003cdiv class='mr-1'\u003e\n\u003ca class=\"btn btn-success\" data-posthog-event=\"Signup: LP Signup Activity\" data-posthog-location=\"body_link_boclips\" data-remote=\"true\" href=\"/subscription/new\"\u003e\u003cspan\u003e\u003cspan\u003eGet Free Access\u003c/span\u003e\u003cspan class=\"\"\u003e for 10 Days\u003c/span\u003e\u003cspan\u003e!\u003c/span\u003e\u003c/span\u003e\u003c/a\u003e\n\u003c/div\u003e\n\u003c/div\u003e\n\u003c/div\u003e\n\u003cdiv class='rp-body'\u003e\n\u003cdiv class='rp-info'\u003e\n\u003cdiv aria-label='Hide resource details' class='rp-hide-info' role='button' tabindex='0'\u003e\u0026times;\u003c/div\u003e\n\u003ci aria-label='Expand resource details' class='rp-expand-info fai fa-solid fa-up-right-and-down-left-from-center' role='button' tabindex='0'\u003e\u003c/i\u003e\n\u003ci aria-label='Compress resource details' class='rp-compress-info fai fa-solid fa-down-left-and-up-right-to-center' role='button' tabindex='0'\u003e\u003c/i\u003e\n\u003cdiv class='rp-rating'\u003e\n\u003cspan class='resource-pool'\u003e\n\u003cspan class='pool-label'\u003ePublisher:\u003c/span\u003e\n\u003cspan class='pool-name'\u003e\n\u003cspan class='text'\u003e\u003ca data-publisher-id=\"30356011\" href=\"/search?publisher_ids%5B%5D=30356011\"\u003eCurated Video\u003c/a\u003e\u003c/span\u003e\n\u003c/span\u003e\n\u003c/span\u003e\n\u003c/div\u003e\n\u003cdiv class='rp-description'\u003e\n\u003cspan class='short-description'\u003eItalian/Eng/NatDoctors believe that a group of Italian children, who can't cry or feel pain, could hold the key to helping millions of people who suffer from more common medical problems.As well as coping with the rare genetic disorder,...\u003c/span\u003e\n\u003cspan class='full-description hide'\u003eItalian/Eng/Nat\u003cbr/\u003eDoctors believe that a group of Italian children, who can't cry or feel pain, could hold the key to helping millions of people who suffer from more common medical problems.\u003cbr/\u003eAs well as coping with the rare genetic disorder, the children are also fighting far more common diseases, such as diabetes.\u003cbr/\u003eU-S experts studying the disorder say the knowledge gained from this tiny community of patients could ultimately benefit millions, by helping isolate the gene which blocks pain.\u003cbr/\u003eA study of the rare genetic disorder, which prevents sufferers from crying or feeling pain, began here at Rome's Bambin Gesu' Hospital on Tuesday.\u003cbr/\u003eIt was inspired by a nine year-old Italian girl whose parents were so frustrated for want of a diagnosis by Italian doctors, that they put out a plea for help on the Internet.\u003cbr/\u003eAn Internet user in Wisconsin, America, directed the Lazzaroni's to Doctor Felicia Axelrod, an expert in hereditary sensory and autonomic neuropathies - or H-S-A-N - at New York University Medical Centre.\u003cbr/\u003eShe explained what the rare genetic disorder means to its victims.\u003cbr/\u003eSOUNDBITE: (English)\u003cbr/\u003e\"The one we have concentrated on here in Italy, because there seems to be more children with this type than in the United States, is H-S-A-N, type 4, and this one is associated with decreased pain perception and the lack of ability to sweat.\"\u003cbr/\u003eSUPER CAPTION: Dr. Felicia Axelrod, New York University Medical\u003cbr/\u003eCentre\u003cbr/\u003eThe Lazzaroni's nine year-old daughter, Alice, suffers from the rare genetic disorder and is now confined to a wheelchair.\u003cbr/\u003eBecause she can feel no pain, she once ran around on a broken leg for months, deforming the bone and necessitating a long spell in a waist-high cast.\u003cbr/\u003eHer father explained how the disorder has affected his daughter's everyday life.\u003cbr/\u003eSOUNDBITE: (Italian)\u003cbr/\u003e\"She needs constant attention because she lacks the fundamental\u003cbr/\u003eperception of pain. The pain feeling returned when she suffered very serious injuries to her bones, in particular to her knees. Therefore she has been forced into the wheelchair for almost two years.\"\u003cbr/\u003eSUPER CAPTION: Sandro Lazzaroni, Alice's father\u003cbr/\u003eDoctor Axelrod and her colleagues have diagnosed Alice as suffering from type 4 H-S-A-N - one of the rarest forms of the disorder.\u003cbr/\u003eBecause Alice can't sweat, even a slight fever could be fatal for her.\u003cbr/\u003eAnother doctor involved in the study explained.\u003cbr/\u003eSOUNDBITE: (English)\u003cbr/\u003e\"When you go up the stairs your blood pressure changes and your heart rate increases. In these kids this doesn't happen so they have a dysfunction. When they stand up in the morning they easily faint. They have syncopies, and it is very important to diagnose this disease with techniques which, on one hand, are suited to an average neurologist who does not see those entities on a daily basis, since they are very rare. On the other hand, these are techniques which can be used by any average neurophisiology technician\".\u003cbr/\u003eSUPER CAPTION: Dr. Max Hilz, Associate Professor, Department of Neurology, New York School of Medicine\u003cbr/\u003eBut as well as coping with this rare disorder, the children are also fighting far more common diseases, such as diabetes.\u003cbr/\u003eDoctors believe the knowledge gained from this tiny community of patients could ultimately benefit millions of people, by helping them isolate the gene which blocks pain.\u003cbr/\u003eRome, Italy - 6 November 1996\u003cbr/\u003e1. MS Bambin Gesu' Hospital with people and children walking\u003cbr/\u003e2. WS St. Peter's cupola in the distance\u003cbr/\u003e3. MS little boy with his father\u003cbr/\u003e4. SOUNDBITE: Doctor Felicia Axelrod\u003cbr/\u003e5. MS Alice Lazzaroni in a wheelchair\u003cbr/\u003e6. CU Alice's broken leg\u003cbr/\u003e7. MS another doctor talking to Alice\u003cbr/\u003e8. SOUNDBITE: Sandro Lazzaroni\u003cbr/\u003e9. MS woman holding little girl\u003cbr/\u003e10. SOUNDBITE: Dr. Max Hilz\u003cbr/\u003e11. 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