{"page":"\u003clink rel=\"stylesheet\" href=\"https://lessonplanet.com/assets/packs/css/resources-572d6a42.css\" /\u003e\n\u003clink rel=\"stylesheet\" href=\"https://lessonplanet.com/assets/packs/css/lp_boclips_stylesheets-f4d0de30.css\" media=\"all\" /\u003e\n\u003cdiv data-title='Imaging technology shows how chemotherapy affects tumours.' data-url='/boclips/videos/5c54c3f8d8eafeecae16548e' data-video-url='/boclips/videos/5c54c3f8d8eafeecae16548e' id='bo_player_modal'\u003e\n\u003cdiv class='boclips-resource-page modal-dialog panel-container'\u003e\n\u003cdiv class='react-notifications-root'\u003e\u003c/div\u003e\n\u003cdiv class='rp-header'\u003e\n\u003cdiv class='rp-type'\u003e\n\u003ci aria-hidden='true' class='fai fa-regular fa-circle-play'\u003e\u003c/i\u003e\nVideo\n\u003c/div\u003e\n\u003ch1 class='rp-title' id='video-title'\u003e\nImaging technology shows how chemotherapy affects tumours.\n\u003c/h1\u003e\n\u003cdiv class='rp-actions'\u003e\n\u003cdiv class='mr-1'\u003e\n\u003ca class=\"btn btn-success\" data-posthog-event=\"Signup: LP Signup Activity\" data-posthog-location=\"body_link_boclips\" data-remote=\"true\" href=\"/subscription/new\"\u003e\u003cspan\u003e\u003cspan\u003eGet Free Access\u003c/span\u003e\u003cspan class=\"\"\u003e for 10 Days\u003c/span\u003e\u003cspan\u003e!\u003c/span\u003e\u003c/span\u003e\u003c/a\u003e\n\u003c/div\u003e\n\u003c/div\u003e\n\u003c/div\u003e\n\u003cdiv class='rp-body'\u003e\n\u003cdiv class='rp-info'\u003e\n\u003cdiv aria-label='Hide resource details' class='rp-hide-info' role='button' tabindex='0'\u003e\u0026times;\u003c/div\u003e\n\u003ci aria-label='Expand resource details' class='rp-expand-info fai fa-solid fa-up-right-and-down-left-from-center' role='button' tabindex='0'\u003e\u003c/i\u003e\n\u003ci aria-label='Compress resource details' class='rp-compress-info fai fa-solid fa-down-left-and-up-right-to-center' role='button' tabindex='0'\u003e\u003c/i\u003e\n\u003cdiv class='rp-rating'\u003e\n\u003cspan class='resource-pool'\u003e\n\u003cspan class='pool-label'\u003ePublisher:\u003c/span\u003e\n\u003cspan class='pool-name'\u003e\n\u003cspan class='text'\u003e\u003ca data-publisher-id=\"30356011\" href=\"/search?publisher_ids%5B%5D=30356011\"\u003eCurated Video\u003c/a\u003e\u003c/span\u003e\n\u003c/span\u003e\n\u003c/span\u003e\n\u003c/div\u003e\n\u003cdiv class='rp-description'\u003e\n\u003cspan class='short-description'\u003eLondon, United Kingdom, 12th November 20081. Patient entering tunnel of PET (Positron Emission Tomography) scanner2. Close up of digital indicators on PET scanner3. SOUNDBITE: (English), Professor Eric Aboagye, Leader, Cancer Research UK...\u003c/span\u003e\n\u003cspan class='full-description hide'\u003eLondon, United Kingdom, 12th November 2008\u003cbr/\u003e1. Patient entering tunnel of PET (Positron Emission Tomography) scanner\u003cbr/\u003e2. Close up of digital indicators on PET scanner\u003cbr/\u003e3. SOUNDBITE: (English), Professor Eric Aboagye, Leader, Cancer Research UK project, Imperial College \u003cbr/\u003e\"It's the equipment, it's the radio tracers, it's the new technology to be able to visualise, see what's happening in a patient's tumour and be able to understand how drugs work in that tumour and that ability to see exactly what is happening inside a patient is what makes the difference. It's means that we can see if the patient has disease, what extent of that disease is and you can properly stratify (assign) the patient to a particular type of treatment, be it surgery, or chemotherapy of a particular type so this is all very exciting.\"\u003cbr/\u003e4. Various Wendy Hogg, breast cancer patient in scanner\u003cbr/\u003e5. SOUNDBITE: (English), Wendy Hogg, breast cancer patient  \u003cbr/\u003e\"You just don't know how you're going to cope until you go through the whole system that is being put before you, because you think you can be strong about things and then you might find you are not going to be strong, as strong as you have thought you could be and you really just try to have a positive view that the people who are dealing with you know what they're doing and are offering you the best possible chances to get through the whole system.\"\u003cbr/\u003e6. Pan wide view of scanner room through door to doctor viewing monitor in next room\u003cbr/\u003e7. Close up of wide screen monitor showing four different views of patient and radiologist in scanning room\u003cbr/\u003e8. Close up of monitor point of view of patient\u003cbr/\u003e9. Close up of scan results showing first image of tumour (left) and second image of tumour after chemotherapy (right)\u003cbr/\u003e10. Close up scan of original tumour\u003cbr/\u003e11. SOUNDBITE:  (English) Kaiyumars Contractor,  Consultant Clinical Research Fellow Imperial College London\u003cbr/\u003e\"In this lady we could detect a twenty per cent change in the uptake of the tracer before and after treatment and that's what's so important to know, because it has been shown that if patients do respond early to treatment and that can be demonstrated in this case, as in this case, then it does lead to improvement in survival and also better response to future therapy as well.\"\u003cbr/\u003e12. Mid shot side view of nurse watching patient at scanner\u003cbr/\u003e13. View of top of patient's head through scanner\u003cbr/\u003e14. Close up of monitor view of nurse talking to patient\u003cbr/\u003e15. Close up monitor view of patient in scanner\u003cbr/\u003e16.SOUNDBITE:  (English) Kaiyumars Contractor, Consultant Clinical Research Fellow Imperial College London\u003cbr/\u003e\"Something like this could not be done with conventional imaging like X-rays, or for example CT scans because anatomical changes, which means changes in tumour size, do take quite long to be demonstrated. Most of them can't be demonstrated before at least six to eight weeks and that's the reason why this technology is very, very useful and important at the moment.\"\u003cbr/\u003e17. Close up of patient Wendy Hogg's head lying down on scanner\u003cbr/\u003e18. Mid shot of patient coming out end of scanner\u003cbr/\u003eIf a cancer patient is to survive and recover, it is vital to diagnose and treat the disease at the earliest possible opportunity.\u003cbr/\u003eNow huge steps in the sophistication of imaging equipment and scanners is making this possible.\u003cbr/\u003eDoctors in the United Kingdom are using Positron Emission Tomography (PET) scanners to detect a tumour and to test whether new drugs are effective.\u003cbr/\u003eSix months ago 59 year old Wendy Hogg, a London teacher discovered a lump in her breast. \u003cbr/\u003eHospital tests confirmed the lump, three centimetres in diameter, was malignant.\u003cbr/\u003eLike millions of other women around the world who have developed breast cancer Wendy faced the fact that she had to have chemotherapy. \u003cbr/\u003eThis treatment usually has severe, debilitating side effects on different parts of the body.\u003cbr/\u003e The hair, the skin and the lining of the mouth and digestive systems, are constantly renewing themselves by allowing cells of all these body tissues to divide to produce a steady supply of new cells. \u003cbr/\u003eBut chemotherapy attacks the dividing cells, whether they are healthy or cancerous, so patients undergoing the treatment like Wendy Hogg suffer hair loss, nausea and subsequent loss of appetite. \u003cbr/\u003eSome people also develop painful mouth ulcers. \u003cbr/\u003eIn most cases patients feel exhausted and unable to carry on their lives as normal. \u003cbr/\u003eHere at Imperial College's research site at Hammersmith Hospital doctors are looking for new methods to treat patients like Wendy Hogg with the help of the Positron Emission Tomography (PET) scanner. \u003cbr/\u003eIt not only allows them to see the tumour, but allows them to compare how effectively a drug is working within a couple of weeks.\u003cbr/\u003eThat can mean patients are subjected to less chemotherapy, or other toxic drugs.\u003cbr/\u003eThe charity Cancer Research UK is so enthusiastic about future possibilities with imaging technology that it helping to fund a multi million dollar investment in the research in partnership with Imperial College.\u003cbr/\u003eProfessor Eric Aboagye, the lead scientist at the unit says the new technology is exciting because it means that doctors are now be able to see what's happening in a patient's tumour and be able to understand how the drugs work inside that tumour.\u003cbr/\u003eAboagye says being able to visualise means doctors can stop an ineffective drug straight away in favour of another which has a better chance of reducing the cancer. \u003cbr/\u003eIn order for the tumour to show up on a scan a safe dose of a mildly radioactive drug is injected into the body, usually through a vein in the arm. \u003cbr/\u003eIt works by emitting nuclear material which gets trapped in the tumour and which in turn is revealed by a ray of detectors inside the scanner.\u003cbr/\u003eAfter just two weeks doctors here were able to identify that chemotherapy had shrunk Wendy Hogg's tumour by twenty per cent, enough for them to remove the rest of the tumour by surgery. \u003cbr/\u003eNormally this diagnosis would have taken three months, meaning Hogg's body would have had to suffer the side effects of the chemotherapy for much longer.\u003cbr/\u003eHogg says when she found out about her cancer she didn't know how she was going to cope. \u003cbr/\u003eShe says people aren't always as strong as they imagine they will be and she was relieved the doctors dealing with her knew what they were doing and offered her the best possible chance of to getting through.\u003cbr/\u003eImperial's clinical research fellow Kaiyumars Contractor says their research confirms that if patients respond early to treatment it leads to an improvement in their chances of survival and their response to any future therapy. \u003cbr/\u003eAt later stages of development the disease becomes far more difficult to treat because it becomes more resistant to drugs.\u003cbr/\u003eCancer Research UK is also hoping the programme will enable progress in the development of new cytostatic drugs which are hoped will have fewer side effects than chemotherapy. \u003cbr/\u003eThese drugs work by stopping the cancer cells from multiplying. \u003cbr/\u003eIt's hoped the PET scan will also prove to be cost effective because it cuts down the use of drugs that aren't working on a patient.  \u003cbr/\u003eCancer drugs affect people differently and what works on one person might not work as well on another. \u003cbr/\u003eDrug treatments can cost up to thirty thousand dollars per patient each year and so doctors are hoping the amount of money saved could be considerable.\u003cbr/\u003e\u003c/span\u003e\n\u003c/div\u003e\n\u003cdiv class='action-container flex justify-between'\u003e\n\u003cbutton aria-expanded='false' aria-label='Read more description' class='rp-full-description' type='button'\u003e\n\u003ci class='fai fa-solid 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